anti-Human CXCR7 Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended CXCR7 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Chemokine (C-X-C Motif) Receptor 7 (CXCR7) Antikörper
  • BEST:LD12308
  • CG3171
  • Dmel\\CG3171
  • LD12308
  • Tre-1
  • anon-WO0170980.16
  • anon-WO0170980.17
  • anon-WO0170981.1
  • sctt
  • tre-1
  • tre1
  • CMKOR1
  • CXC-R7
  • CXCR-7
  • CXCR7
  • GPR159
  • RDC-1
  • RDC1
  • AW541270
  • Cmkor1
  • Cxcr7
  • Rdc1
  • Trapped in endoderm 1
  • ORF 74; similar to Kaposi's sarcoma-associated herpesvirus ORF 74
  • atypical chemokine receptor 3
  • Tre1
  • MmrVgp88
  • ACKR3
  • Ackr3
Epitop
AA 184-213
40
31
24
18
12
11
10
10
10
10
8
6
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
230
133
111
25
24
21
8
7
4
4
4
4
1
1
1
1
1
1
1
Wirt
Kaninchen
158
90
18
7
1
Klonalität
Polyklonal
Konjugat
Dieser CXCR7 Antikörper ist unkonjugiert
17
13
12
12
11
11
11
10
10
10
8
7
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
155
128
65
56
55
31
25
22
9
5
5
4
3
2
2
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN1387536
$ 318.45
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN741990 IF (p) IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN1396946 IF (p) Alexa Fluor 350 Rabbit IgG AA 184-213 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1396947 IF (p) Alexa Fluor 488 Rabbit IgG AA 184-213 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1396948 IF (p) Alexa Fluor 555 Rabbit IgG AA 184-213 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1396951 IF (p) FITC Rabbit IgG AA 184-213 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1396949 IF (p) Alexa Fluor 647 Rabbit IgG AA 184-213 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1414823 IF (p) Cy5 Rabbit IgG AA 184-213 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1414824 IF (p) Cy5.5 Rabbit IgG AA 184-213 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1414825 IF (p) Cy7 Rabbit IgG AA 184-213 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1414822 IF (p) Cy3 Rabbit IgG AA 184-213 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2812090 IF (p) Alexa Fluor 594 Rabbit IgG AA 312-362 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2808559 IF (p) Alexa Fluor 594 Rabbit IgG AA 184-213 Anmelden zum Anzeigen Polyclonal 0
1 ABIN892841 IF (p) Alexa Fluor 350 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN892843 IF (p) Alexa Fluor 647 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN892842 IF (p) Alexa Fluor 555 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN892844 IF (p) Alexa Fluor 488 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN741997 IF (p) FITC Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN741994 IF (p) Cy5 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN741995 IF (p) Cy5.5 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN741993 IF (p) Cy3 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0

General

Antigen Chemokine (C-X-C Motif) Receptor 7 (CXCR7) Antikörper
Epitop AA 184-213
(40), (31), (24), (18), (12), (11), (10), (10), (10), (10), (8), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(230), (133), (111), (25), (24), (21), (8), (7), (4), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(158), (90), (18), (7), (1)
Klonalität
Polyklonal
Konjugat Dieser CXCR7 Antikörper ist unkonjugiert
(17), (13), (12), (12), (11), (11), (11), (10), (10), (10), (8), (7), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(155), (128), (65), (56), (55), (31), (25), (22), (9), (5), (5), (4), (3), (2), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CXCR7 Antikörper

Target Details CXCR7 Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human CXCR7/RDC1
Isotyp IgG
Plasmids, Primers & others

Target Details CXCR7

Produktdetails anti-CXCR7 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Cxcr7/Rdc1 (CXCR7 Antibody Abstract)
Hintergrund

Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.

Subcellular location: Extracellular

Synonyms: RDC1, CXCR7, RDC-1, CMKOR1, CXC-R7, CXCR-7, GPR159, Atypical chemokine receptor 3, C-X-C chemokine receptor type 7, Chemokine orphan receptor 1, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, ACKR3

Gen-ID 57007
UniProt P25106
Pathways Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling

Anwendungsinformationen

Produktdetails anti-CXCR7 Antikörper Target Details CXCR7 Handhabung Bilder zurück nach oben
Applikations-hinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CXCR7 Antikörper Target Details CXCR7 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Bilder

Produktdetails anti-CXCR7 Antikörper Target Details CXCR7 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 184-213) antibody (ABIN1387536) Formalin-fixed and paraffin embedded rat brain labeled with Anti-CXCR7/RDC1 Polyclona...
Immunohistochemistry (IHC) image for anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 184-213) antibody (ABIN1387536) Formalin-fixed and paraffin embedded rat kidney labeled with Anti-CXCR7/RDC1 Polyclon...