Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Wählen Sie die gewünschte Spezies
Data show that activated PKA phosphorylates the 19S subunit, Rpn6/PSMD11 (regulatory particle non-ATPase 6/proteasome subunit D11) at Ser14.
human embryonic stem cells (hESCs) exhibit high proteasome activity that is correlated with increased levels of the 19S proteasome subunit PSMD11 (known as RPN-6 in Caenorhabditis elegans) and a corresponding increased assembly of the 26S/30S proteasome
AMP-activated protein kinase is able to interact physically with this subunit and modify its phosphorylation status.
interaction with ubiquitinated NF-kappaB2/p100
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene.
proteasome 26S non-ATPase subunit 11
, 26S proteasome non-ATPase regulatory subunit 11B
, 26S proteasome regulatory subunit RPN6-B
, proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
, 26S proteasome non-ATPase regulatory subunit 11
, 26S proteasome regulatory subunit 9
, 26S proteasome regulatory subunit RPN6
, 26S proteasome regulatory subunit S9
, 26S proteasome regulatory subunit p44.5