Produkt kostenlos erhalten?
Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validierenRelevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
---|---|---|---|---|---|---|---|---|---|---|
1 | ABIN202447 | WB | Rabbit | IgG | C-Term | Anmelden zum Anzeigen | Polyclonal | 0 | ||
1 | ABIN1927533 | IF IP IHC (p) WB | Rabbit | IgG | AA 1-50 | Anmelden zum Anzeigen | Polyclonal | 0 |
General |
|
---|---|
Antigen | Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5) Antikörper |
Epitop | C-Term Alternativen |
Reaktivität | Rind (Kuh), Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio) Alternativen |
Wirt | Kaninchen Alternativen |
Klonalität | |
Konjugat | Dieser PSMC5 Antikörper ist unkonjugiert Alternativen |
Applikation |
Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
Alternativen
|
![]() |
1 Publikation vorhanden |
Hersteller | Anmelden zum Anzeigen |
Produktdetails anti-PSMC5 AntikörperTarget Details PSMC5 Anwendungsinformationen Handhabung Referenzen für anti-PSMC5 Antikörper (ABIN2780449) Bilder |
|
Sequenz | AEVKGVCTEA GMYALRERRV HVTQEDFEMA VAKVMQKDSE KNMSIKKLWK |
Homologie | Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100% |
Produktmerkmale | This is a rabbit polyclonal antibody against PSMC5. It was validated on Western Blot using a cell lysate as a positive control. |
Reinigung | Protein A purified |
Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human PSMC5 |
Target Details PSMC5Produktdetails anti-PSMC5 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-PSMC5 Antikörper (ABIN2780449) Bilder zurück nach oben |
|
Antigen | |
Andere Bezeichnung | PSMC5 (PSMC5 Antibody Abstract) |
Hintergrund |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.PSMC5 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Alias Symbols: S8, p45, SUG1, SUG-1, TBP10, TRIP1, p45/SUG Protein Interaction Partner: HUWE1, KRT38, KRT40, PDCL, CIITA, FOS, THAP11, SUMO2, SUMO3, Gabbr2, PSMD14, UBE3C, UBC, PSMB4, RPS13, RPL29, PSMD12, PSMD11, PSMD8, PSMD3, PSMD1, PSMC6, DYNC1I2, ABCF1, KCMF1, UCHL5, KIAA0368, UBR4, ADRM1, MAP2, PARK2, FBXO6, RORA, PSMC4, BAG3, HIV2gp7, Protein Size: 406 |
Molekulargewicht | 46 kDa |
Gen-ID | 5705 |
NCBI Accession | NM_002805, NP_002796 |
UniProt | P62195 |
Pathways | Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA |
AnwendungsinformationenProduktdetails anti-PSMC5 Antikörper Target Details PSMC5 Handhabung Referenzen für anti-PSMC5 Antikörper (ABIN2780449) Bilder zurück nach oben |
|
Applikationshinweise | Optimal working dilutions should be determined experimentally by the investigator. |
Kommentare |
Antigen size: 406 AA |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails anti-PSMC5 Antikörper Target Details PSMC5 Anwendungsinformationen Referenzen für anti-PSMC5 Antikörper (ABIN2780449) Bilder zurück nach oben |
|
Format | Liquid |
Konzentration | Lot specific |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
Konservierungsmittel | Sodium azide |
Vorsichtsmaßnahmen | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handhabung | Avoid repeated freeze-thaw cycles. |
Lagerung | -20 °C |
Informationen zur Lagerung | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Referenzen für anti-PSMC5 Antikörper (ABIN2780449)Produktdetails anti-PSMC5 Antikörper Target Details PSMC5 Anwendungsinformationen Handhabung Bilder zurück nach oben |
|
Allgemeine Veröffentlichungen |
Inoue, Kon, Ajima, Ohkura, Tani, Yokota, Sutoh: "MYO18B interacts with the proteasomal subunit Sug1 and is degraded by the ubiquitin-proteasome pathway." in: Biochemical and biophysical research communications, Vol. 342, Issue 3, pp. 829-34, 2006 |
BilderProduktdetails anti-PSMC5 Antikörper Target Details PSMC5 Anwendungsinformationen Handhabung Referenzen für anti-PSMC5 Antikörper (ABIN2780449) zurück nach oben |
|
Bilder des Herstellers |
|