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Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validierenRelevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
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3.2595015 | ABIN2786719 | WB | Rabbit | Middle Region | Anmelden zum Anzeigen | Polyclonal | 0 | |||
1 | ABIN464041 | WB | Rabbit | IgG | AA 107-156 | Anmelden zum Anzeigen | Polyclonal | 0 | ||
1 | ABIN470012 | WB | Rabbit | AA 143-192 | Anmelden zum Anzeigen | Polyclonal | 0 |
General |
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Antigen | Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) Antikörper |
Epitop | Middle Region Alternativen |
Reaktivität | Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio) Alternativen |
Wirt | Kaninchen Alternativen |
Klonalität | |
Konjugat | Unkonjugiert Alternativen |
Applikation |
Western Blotting (WB)
Alternativen
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Hersteller | Anmelden zum Anzeigen |
ProduktdetailsAntigendetails Anwendungsinformationen Handhabung Bilder |
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Blocking Peptide | Zu diesem Produkt passt das Blocking Peptide ABIN982351. |
Sequenz | YLKQVLGQMV IDEELLGDGH SYSPRAIHSW LTRAMYSRRS KMNPLWNTMV |
Homologie | Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92% |
Produktmerkmale | This is a rabbit polyclonal antibody against PSMB4. It was validated on Western Blot using a cell lysate as a positive control. |
Reinigung | Affinity Purified |
Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human PSMB4 |
AntigendetailsProduktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben |
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Antigen | |
Andere Bezeichnung | PSMB4 (PSMB4 Antibody Abstract) |
Hintergrund |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB4 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. Alias Symbols: HN3, HsN3, PROS26, PROS-26 Protein Interaction Partner: FSD2, UBC, PSMA3, PSMD14, PSMD9, PSMC5, PSMA5, HNRNPA1, PSMG3, POMP, RPP38, PSMB8, PSMB7, PSMB6, PSMB5, PSMB3, PSMB2, PSMB1, PSMA7, PSMA6, PSMA4, PSMA1, KIF5B, HNRNPA2B1, EPB41L1, DDB2, PSMA2, PARK2, BAG3, PRKCA, SMAD1, CFTR, IQCB1, SULT1A4, PSMA8, SYAP1, Protein Size: 264 |
Molekulargewicht | 29 kDa |
Gen-ID | 5692 |
NCBI Accession | NM_002796, NP_002787 |
UniProt | P28070 |
Pathways | Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA |
AnwendungsinformationenProduktdetails Antigendetails Handhabung Bilder zurück nach oben |
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Applikationshinweise | Optimal working dilutions should be determined experimentally by the investigator. |
Kommentare |
Antigen size: 264 AA |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben |
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Format | Liquid |
Konzentration | Lot specific |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
Konservierungsmittel | Sodium azide |
Vorsichtsmaßnahmen | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handhabung | Avoid repeated freeze-thaw cycles. |
Lagerung | -20 °C |
Informationen zur Lagerung | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
BilderProduktdetails Antigendetails Anwendungsinformationen Handhabung zurück nach oben |
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Bilder des Herstellers |