anti-Kaninchen Proteasome (Prosome, Macropain) Subunit, alpha Type, 6 Antikörper für Western Blotting

Recommended Proteasome (Prosome, Macropain) Subunit, alpha Type, 6 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Proteasome (Prosome, Macropain) Subunit, alpha Type, 6 (PSMA6) Antikörper
  • IOTA
  • PROS27
  • p27K
  • proteasome (prosome, macropain) subunit, alpha type 6
  • proteasome subunit alpha 6
  • Psma6
  • PSMA6
Epitop
N-Term
2
2
2
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Schaf, Yeast (Saccharomyces cerevisiae), Zebrafisch (Danio rerio)
51
31
31
15
13
6
5
4
4
4
4
2
2
2
1
1
1
1
1
Wirt
Kaninchen
26
25
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
47
18
12
10
9
4
4
2
1
1
Optionen
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Bilder

Produktnummer ABIN2778812
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.283734 ABIN2778813 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN2743870 IHC (p) WB Rabbit IgG AA 26-75 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2577389 WB Mouse IgG1 Anmelden zum Anzeigen MCP106 0
1 ABIN2627298 IP IHC WB Mouse IgG1 Anmelden zum Anzeigen MCP20 0
1 ABIN1927444 IP WB Rabbit IgG AA 196-246 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1836950 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0

General

Antigen Proteasome (Prosome, Macropain) Subunit, alpha Type, 6 (PSMA6) Antikörper
Epitop N-Term
(2), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Schaf, Yeast (Saccharomyces cerevisiae), Zebrafisch (Danio rerio)
(51), (31), (31), (15), (13), (6), (5), (4), (4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(26), (25)
Klonalität
Polyklonal
Applikation Western Blotting (WB)
(47), (18), (12), (10), (9), (4), (4), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN982345.
Sequenz EYAFKAINQG GLTSVAVRGK DCAVIVTQKK VPDKLLDSST VTHLFKITEN
Homologie Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%
Produktmerkmale This is a rabbit polyclonal antibody against PSMA6. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human PSMA6

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung PSMA6 (PSMA6 Antibody Abstract)
Hintergrund The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA6 is a member of the peptidase T1A family, which is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IOTA, MGC22756, MGC2333, MGC23846, PROS27, p27K
Protein Interaction Partner: UBC, RNF170, LIMD2, C19orf57, TRIM39, ZBTB44, CADM1, HUWE1, PSMA3, RTP5, KRTAP4-2, AURKA, PSMD14, MDM2, PSMA5, PSMG3, PSMG2, PSMG1, RNF2, PSMB8, PSMB7, PSMB6, PSMB5, PSMB4, PSMB3, PSMB2, PSMB1, PSMA7, PSMA4, PSMA1, HNRNPA2B1, PYCRL, RPP38, RPP30, CAST, PS
Protein Size: 246
Molekulargewicht 27 kDa
Gen-ID 5687
NCBI Accession NM_002791, NP_002782
UniProt P60900
Pathways Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 246 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Bennett, Xu, Clarke, Zondervan, Parish, Palmer, Cardon, Peto, Lathrop, Collins: "The exon 1-8C/G SNP in the PSMA6 gene contributes only a small amount to the burden of myocardial infarction in 6946 cases and 2720 controls from a United Kingdom population." in: European journal of human genetics : EJHG, Vol. 16, Issue 4, pp. 480-6, 2008

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Proteasome (Prosome, Macropain) Subunit, alpha Type, 6 (PSMA6) (N-Term) antibody (ABIN2778812) WB Suggested Anti-PSMA6 Antibody Titration: 0.2-1 ug/ml
Positive Control...