-
Results suggest that proteasome subunit alpha type 6 (PSMA6) serves as an attractive target with a high therapeutic index for lung cancer.
-
The 5' untranslated region of PSMA6 gene contains a single nucleotide polymorphism -8 C/G associated with End-stage kidney disease and might be a protective factor for the disease.
-
These data indicate that hepatic expression of PSMA6, which is upregulated during viral hepatitis, likely depends on TLR3 activation and, that PSMA6 affects the expression of immunoregulatory ISG15, a proviral factor in the pathogenesis of hepatitis C virus infection.
-
Data indicate that proteasome subunit alpha 6 (PSMA6) direct contacts with proteasome subunit alpha 7 (PSMA7) tetradecamer.
-
Our results provide evidence on new T1DM-susceptible loci in the PSMA3, PSMA6 and PSMC6 proteasome genes and give a new insight into the T1DM pathogenesis
-
Evidence of a sex-specific association of PSMA6 genetic variants with subtypes of juvenile idiopathic arthritis.
-
The data show that LMP2 and PSMA6 gene polymorphism is not a risk factor of ischemic stroke in Ukrainian population.
-
The PSMA6 variant rs1048990 appears to affect susceptibility to ischaemic stroke in both caucasian and african american populations.
-
The G allele of PSMA6-8C/G polymorphism is a risk factor associated with increased coronary artery disease susceptibility. [Meat-analysis]
-
Investigation suggests that -8 C/G variant of PSMA6 gene may be associated with T2DM and diabetes-related metabolic traits in Chinese Dongxiang and Han populations.
-
PSMA6 polymorphisms were not associated with phenotype of coronary atherosclerosis.
-
the G-allele of the PSMA6-8C>G polymorphism is a possible survival prognosticator in multiple myeloma
-
A total of 1330 cases and 2554 controls from Japanese and Korean populations for PSMA6 genotypes were investigated, and no evidence of the association was obtained in both Japanese and Korean populations.
-
PSMA6 rs_1048990 polymorphism may contribute to MI susceptibility in type 2 diabetes.
-
common SNP (minor allele frequency of 0.35) in the proteasome subunit alpha type 6 gene (PSMA6) conferring risk of myocardial infarction in the Japanese population
-
The reported genotype in PSMA6 appears not to contribute appreciably to myocardial infarction, but may contribute slightly to atherosclerosis in the present study population.
-
2 SNPs at positions -110 & -8 from translation start, in the promoter region & 5'UTR of PSMA6 were analyzed; genotype -8CG was more frequent in type 2 diabetes patients & haplotype C-110/G-8, compared to C-110/C-8 was associated with higher risk of NIDDM
-
The GG genotype for rs1048990 was less frequent in the UK population than in the Japanese population, and was associated with an odds ratio for mi of 1.09 per G allele in a co-dominant genetic model and 1.32 in a recessive genetic model.
-
Our results indicate that the PSMA6 variant rs1048990 is a risk factor of myocardial infarction in the Chinese population.
-
Obtained data suggest the LMP2 and PSMA6 gene polymorphisms significance as the risk factors of essential hypertension in adolescents.
