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The expression level of psma6 in AML-M5 patients with complete remission was higher than that in AML-M5 patients without remission.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
macropain subunit C3
, multicatalytic endopeptidase complex subunit C3
, proteasome component C3
, proteasome subunit alpha type-2
, proteasome alpha 2 subunit
, proteasome subunit XC3
, proteasome subunit HC3