anti-Kaninchen PSMA1 Antikörper für Western Blotting

Recommended PSMA1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Proteasome (Prosome, Macropain) Subunit, alpha Type, 1 (PSMA1) Antikörper
  • PSMA1
  • pros30
  • DDBDRAFT_0204226
  • DDBDRAFT_0214956
  • DDB_0204226
  • DDB_0214956
  • C2
  • HC2
  • Pros-30
  • alpha-type
  • NU
  • PROS30
  • CC2
  • zgc:92726
  • 143314_at
  • Alpha-6
  • CG4904
  • Dmel\CG4904
  • PROS-35
  • PROS-Dm35
  • Pros-35
  • Pros-Dm35
  • Prosalpha6
  • alpha6
  • alpha_dm
  • anon-SAGE:Wang-116
  • pros 35
  • pros35
  • proteasome subunit alpha 1
  • proteasome subunit alpha type 1
  • 20S proteasome subunit C2
  • proteasome (prosome, macropain) subunit, alpha type 1
  • proteasome subunit alpha 1 L homeolog
  • Proteasome alpha6 subunit
  • PSMA1
  • psma1
  • CNB05540
  • psmA1
  • Psma1
  • psma1.L
  • Prosalpha6
Epitop
C-Term
19
12
7
4
4
4
2
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
62
20
20
11
6
5
5
5
4
4
3
3
3
3
3
1
1
1
Wirt
Kaninchen
49
10
4
Klonalität
Polyklonal
Konjugat
Dieser PSMA1 Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
60
33
15
7
4
2
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2778810
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2563753 ABIN2778811 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 1
1 ABIN214137 IHC (p) WB Rabbit IgG AA 170-219 Anmelden zum Anzeigen Polyclonal 0
1 ABIN203038 WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN352715 ELISA WB Rabbit IgG AA 256-269 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1927423 IP WB Rabbit IgG AA 213-263 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Proteasome (Prosome, Macropain) Subunit, alpha Type, 1 (PSMA1) Antikörper
Epitop C-Term
(19), (12), (7), (4), (4), (4), (2), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
(62), (20), (20), (11), (6), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (1), (1), (1)
Wirt Kaninchen
(49), (10), (4)
Klonalität
Polyklonal
Konjugat Dieser PSMA1 Antikörper ist unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(60), (33), (15), (7), (4), (2), (2), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-PSMA1 Antikörper

Target Details PSMA1 Anwendungsinformationen Handhabung Referenzen für anti-PSMA1 Antikörper (ABIN2778810) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN982337.
Sequenz TYLERHMSEF MECNLNELVK HGLRALRETL PAEQDLTTKN VSIGIVGKDL
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Produktmerkmale This is a rabbit polyclonal antibody against PSMA1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human PSMA1

Target Details PSMA1

Produktdetails anti-PSMA1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-PSMA1 Antikörper (ABIN2778810) Bilder zurück nach oben
Antigen
Andere Bezeichnung PSMA1 (PSMA1 Antibody Abstract)
Hintergrund The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA1 is a member of the peptidase T1A family which is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
Alias Symbols: HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30
Protein Interaction Partner: PRDM14, CEP70, CCDC102B, GNPTAB, CEP72, KCTD9, ROPN1, ABI3, SH3GLB1, APIP, LDOC1, MTUS2, MAPRE3, MAPRE1, IKZF3, MID2, EHMT2, PNMA2, IKZF1, TRIM10, HUWE1, HOMER3, PNMA1, KRT38, BLZF1, MAD1L1, MKRN3, REL, PSMA3, MLH1, KRT31, KRT15, KRTAP5-9, GOLGA2, CDA, CC
Protein Size: 263
Molekulargewicht 29 kDa
Gen-ID 5682
NCBI Accession NM_002786, NP_002777
UniProt P25786
Pathways Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA

Anwendungsinformationen

Produktdetails anti-PSMA1 Antikörper Target Details PSMA1 Handhabung Referenzen für anti-PSMA1 Antikörper (ABIN2778810) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 263 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-PSMA1 Antikörper Target Details PSMA1 Anwendungsinformationen Referenzen für anti-PSMA1 Antikörper (ABIN2778810) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PSMA1 Antikörper (ABIN2778810)

Produktdetails anti-PSMA1 Antikörper Target Details PSMA1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Cron, Zhu, Kushwaha, Hsieh, Merzon, Rameseder, Chen, DAndrea, Kozono: "Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer." in: PLoS ONE, Vol. 8, Issue 9, pp. e73710, 2013

Allgemeine Veröffentlichungen

Conticello, Harris, Neuberger: "The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G." in: Current biology : CB, Vol. 13, Issue 22, pp. 2009-13, 2003

Bilder

Produktdetails anti-PSMA1 Antikörper Target Details PSMA1 Anwendungsinformationen Handhabung Referenzen für anti-PSMA1 Antikörper (ABIN2778810) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Proteasome (Prosome, Macropain) Subunit, alpha Type, 1 (PSMA1) (C-Term) antibody (ABIN2778810) WB Suggested Anti-PSMA1 Antibody Titration: 0.2-1 ug/ml
Positive Control...
Western Blotting (WB) image for anti-Proteasome (Prosome, Macropain) Subunit, alpha Type, 1 (PSMA1) (C-Term) antibody (ABIN2778810) Sample Type: Human non-small cell lung cancer (NCI-460)Primary Dilution: 1:2000Second...