Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Rat (Rattus) Antikörper:
anti-Mouse (Murine) Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Polyclonal MAT1A Primary Antibody für ICC, IF - ABIN4332790
Yang, Cho, Li, Peng, Ko, Mato, Lu: MicroRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular carcinoma. in The Journal of clinical investigation 2013
Show all 2 Pubmed References
Cow (Bovine) Polyclonal MAT1A Primary Antibody für WB - ABIN2776786
Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: Transcriptome analysis of human gastric cancer. in Mammalian genome : official journal of the International Mammalian Genome Society 2005
Show all 2 Pubmed References
Human Polyclonal MAT1A Primary Antibody für IHC (p), WB - ABIN656632
Bing, Zhu, Yu, Li, Liu, Li, Wang, Qi, Guo, Yuan, He, Liu, Liu: Glucocorticoid-induced S-adenosylmethionine enhances the interferon signaling pathway by restoring STAT1 protein methylation in hepatitis B virus-infected cells. in The Journal of biological chemistry 2014
interplay between MATalpha1, c-Myc (zeige MYC Antikörper), and Maf (zeige MAF Antikörper) proteins, and their deregulation during chronic cholestasis may facilitate cholangiocarcinoma oncogenesis
Of the 22 single nucleotide polymorphisms studied, the rs8193 polymorphism lying in the micro-RNA binding site of 3'-UTR (zeige UTS2R Antikörper) of CD44 (zeige CD44 Antikörper) was significantly (P=.0270) associated with RT-induced adverse skin reactions. Generalized multifactor dimensionality reduction analysis showed significant (P=.0107) gene-gene interactions between MAT1A and CD44 (zeige CD44 Antikörper).
A compound mutation of the methionine adenosyltransferase 1A (MAT1A) gene, c.345delA and c.529C>T, was identified in the patient, and His father and mother were found to be heterozygous for the c.345delA mutation and c.529C>T mutation, respectively.
S-adenosyl-L-methionine (zeige AS3MT Antikörper) diminishes hepatitis C virus expression by altering MAT1A/2A signaling in hepatocytes.
5-Aza-CdR (zeige RUNX1T1 Antikörper) showed no effects on MAT2A (zeige MAT2A Antikörper) methylation.
The mutations in the other 10 patients showed autosomal recessive inheritance and included eight novel MAT1A mutations.
Liver-specific isoenzyme MAT1A is genetically linked with an inborn metabolic disorder of hypermethioninemia, as well as a ubiquitously expressed isoenzyme MAT2A (zeige MAT2A Antikörper), whose enzymatic activity is regulated by an associated subunit MAT2B (zeige MAT2B Antikörper).
Methionine adenosyltransferase I/III deficiency is caused by mutations in the MAT1A gene. (Review)
upregulation of miR (zeige MLXIP Antikörper)-664, miR (zeige MLXIP Antikörper)-485-3p, and miR (zeige MLXIP Antikörper)-495 contributes to lower MAT1A expression in HCC (zeige FAM126A Antikörper), and enhanced tumorigenesis may provide potential targets for HCC (zeige FAM126A Antikörper) therapy.
Report SNPs that are highly associated with hepatic GNMT (zeige GNMT Antikörper) protein expression and the coordinate regulation of MAT1A levels.
MAT1A is required for normal VLDL assembly and plasma lipid homeostasis in mice. Impaired VLDL synthesis, mainly due to SAMe deficiency, contributes to NAFLD (zeige TSC2 Antikörper) development in MAT1A-KO mice.
DUSP1 (zeige DUSP1 Antikörper) mRNA and protein levels are lower in Mat1a knockout livers and fall rapidly in cultured hepatocytes.
Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A
MAT1A knockout hepatocytes have more baseline DNA synthesis but no mitogenic response to hepatocyte growth factor (zeige HGF Antikörper). MAT1A-produced SAMe has a major role in ERK (zeige EPHB2 Antikörper) signaling & cyclin D1 (zeige CCND1 Antikörper) regulation during liver regeneration & mitogenic signal response.
Mat1a(-/-) mice have expansion of liver stem cells as they age. These cells have increased expression of several oncogenes and are tumorigenic in vivo.
C/EBPbeta (zeige CEBPB Antikörper) plays an important role in epigenetic regulation of the mature hepatic gene MAT1A
By 1 month of age, genomic instability increases in livers of Mat1a knockout mice, possibly due to reduced APEX1 (zeige APEX1 Antikörper) levels
CD133(+)CD45(-) oval cells isolated from premalignant 16-month-old Mat1a(-/-) mice demonstrated significant resistance to transforming growth factor-beta-induced apoptosis compared to CD133(-) cells.
This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.
, S-adenosylmethionine synthase isoform type-1
, S-adenosylmethionine synthetase isoform type-1
, adoMet synthase 1
, adoMet synthetase 1
, methionine adenosyltransferase 1
, methionine adenosyltransferase I/III
, S - adenosylmethionine synthetase