anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) Antikörper

6 Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) Antikörper von 2 Herstellern verfügbar auf www.antikoerper-online.de.

Datenqualität
  • 5
Typ
  • 6
    Primärantikörper
Antigen
  • 6
Reaktivität
  • 5
  • 1
Anwendung
  • 5
  • 5
  • 1
  • 1
  • 1
Wirt
  • 6
Klonalität
  • 6
Bindungsspezifität
  • 2
  • 1
  • 1
  • 1
  • 1
Isotyp
  • 6
Format
  • 6
6 Produkte
ReaktivitätHuman
Applikation DB, ELISA
Bestellinformationen Artikelnr. ABIN3030641
$452.38
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
ReaktivitätHuman
Applikation ELISA, WB
Bestellinformationen Artikelnr. ABIN3028606
$452.38
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
ReaktivitätMaus
Applikation ELISA, WB
Bestellinformationen Artikelnr. ABIN3030639
$452.38
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
ReaktivitätHuman
Applikation ELISA, WB
Bestellinformationen Artikelnr. ABIN3030638
$452.38
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
ReaktivitätHuman
Applikation ELISA, WB
Bestellinformationen Artikelnr. ABIN3030640
$452.38
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
ReaktivitätHuman
Applikation FACS, IF, IHC, WB
Bestellinformationen Artikelnr. ABIN2797433
ISO
$467.50
400 μL
Zzgl. Versandkosten $45.00
Lieferung in 6 bis 8 Werktagen
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Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) Antigen-Profil

Protein Überblick

This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene\; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.

Alternative names and synonyms associated with Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A)

  • cyclin-dependent kinase inhibitor 2A (Cdkn2a) Antikörper
  • cyclin-dependent kinase inhibitor 2A (LOC100731972) Antikörper
  • cyclin-dependent kinase inhibitor 2A (LOC100340625) Antikörper
  • cyclin dependent kinase inhibitor 2A (CDKN2A) Antikörper
  • ARF Antikörper
  • ARF-INK4a Antikörper
  • CDK4I Antikörper
  • CDKN2 Antikörper
  • CMM2 Antikörper
  • INK4 Antikörper
  • INK4A Antikörper
  • INK4a-ARF Antikörper
  • Ink4a/Arf Antikörper
  • MLM Antikörper
  • MTS-1 Antikörper
  • MTS1 Antikörper
  • P14 Antikörper
  • P14ARF Antikörper
  • P16 Antikörper
  • p16(INK4a) Antikörper
  • P16-INK4A Antikörper
  • p16Cdkn2a Antikörper
  • P16INK4 Antikörper
  • p16INK4a Antikörper
  • P19 Antikörper
  • p19 Antikörper
  • P19ARF Antikörper
  • Pctr1 Antikörper
  • TP16 Antikörper

Bezeichner auf Proteinebene für CDKN2A

CDK4I , Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4) , cell cycle inhibitor , cell cycle regulator , cyclin-dependent kinase 4 inhibitor A , cyclin-dependent kinase inhibitor 2a p16Ink4a , cyclin-dependent kinase inhibitor 2a p19Arf , p16-INK4 , p16-INK4a , CDK4 inhibitor p16-INK4 , cell cycle negative regulator beta , cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) , multiple tumor suppressor 1 , cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4) , cyclin-dependent kinase inhibitor 2A, isoforms 1/2 , cyclin-dependent kinase inhibitor protein , mitochondrial smARF

GENE ID SPEZIES
25163 Rattus norvegicus
100731972 Cavia porcellus
100340625 Oryctolagus cuniculus
1029 Homo sapiens
12578 Mus musculus
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