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TUBB2A missense mutation is associated with arthrogryposis multiplex congenita, brain abnormalities, and severe developmental delay.
study associates mutations in TUBB2A with the spectrum of "tubulinopathy" phenotypes
This is the first study showing that paclitaxel neuropathy risk is influenced by polymorphisms regulating the expression of a beta-tubulin gene.
Class II beta-tubulin may be very useful for immunohistochemical diagnosis of classical Hodgkin's lymphoma.
Data suggest that the increased betaII- and betaIII-tubulin contributed significantly to the resistance phenotype.
A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.
This protein has been found differentially expressed in the anterior cingulate cortex from patients with schizophrenia
Data show that connexin 43 (cx43) binds alpha-tubulin equally well as beta-tubulin, and that ZO-1 binds directly to Cx43.
lack of mutations in early stage lung cancer
Mutations of the beta-tubulin gene, which might be a contraindication for chemotherapy based on taxans, were very rare events in gastric cancer.
Smad3 was bound to beta2-tubulin in a TGF-beta1/cGMP-dependent manner.
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain (By similarity).
class IIa beta-tubulin
, tubulin beta class IIa
, tubulin beta-2A chain
, tubulin, beta polypeptide 2
, tubulin, beta polypeptide
, tubulin, beta 2A
, tubulin, beta 2
, tubulin, beta 2 class II
, LOW QUALITY PROTEIN: tubulin beta-2A chain