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anti-Human MAPK9 Antikörper:
anti-Mouse (Murine) MAPK9 Antikörper:
anti-Rat (Rattus) MAPK9 Antikörper:
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Human Polyclonal MAPK9 Primary Antibody für IHC (p), WB - ABIN1882172
Gupta, Barrett, Whitmarsh, Cavanagh, Sluss, Dérijard, Davis: Selective interaction of JNK protein kinase isoforms with transcription factors. in The EMBO journal 1996
Show all 4 Pubmed References
Human Polyclonal MAPK9 Primary Antibody für ELISA, WB - ABIN4327970
Leppä, Bohmann: Diverse functions of JNK signaling and c-Jun in stress response and apoptosis. in Oncogene 1999
The MAP kinase (zeige MAPK1 Antikörper) JNK2 mediates cigarette smoke-induced tissue factor (zeige F3 Antikörper) activation, arterial thrombosis and reactive oxygen species production.
We found p-JNK2 up-regulation in AUC and its early down-regulation in UC-CRC (zeige CALR Antikörper) and CRC (zeige CALR Antikörper) carcinogenesis.
JNK2 was a novel direct target of miR (zeige MLXIP Antikörper)-20a-5p.
The release of infectious respiratory syncytial virus (RSV) virions from infected cells was significantly reduced by JNK1 (zeige MAPK8 Antikörper)/2 siRNA knockdown, implicating JNK1 (zeige MAPK8 Antikörper)/2 as a key host factor for RSV virus production.
PXR (zeige NR1I2 Antikörper) regulates the intestinal epithelial barrier during inflammation by modulating cytokine-induced MLCK (zeige MYLK Antikörper) expression and JNK1 (zeige MAPK8 Antikörper)/2 activation
Phloretin is able to inhibit NSCLC A549 cell growth by inducing apoptosis through P38 MAPK (zeige MAPK14 Antikörper) and JNK1 (zeige MAPK8 Antikörper)/2 pathways, and therefore may prove to be an adjuvant to the treatment of non-small cell lung cancer
In hepatocytes, JNK1 (zeige MAPK8 Antikörper) and JNK2 appear to have combined effects in protecting from drug-induced liver injury.
Inhibition of JNK1 (zeige MAPK8 Antikörper)/2 activity suppressed Hedgehog (zeige SHH Antikörper) pathway activity in acquired chemoresistant cancer cells.
although JNK (zeige MAPK8 Antikörper) activation and RIP3 (zeige RIPK3 Antikörper) expression are induced by FS, neither contributes to the liver injury.
These data suggest that JNK1 (zeige MAPK8 Antikörper)/2 may play an important role in promoting the replication of Penicillium marneffei.
activation of JNK (zeige MAPK8 Antikörper) in the endoplasmic reticulum stress response precedes activation of XBP1 (zeige XBP1 Antikörper).
JNK-2 regulates aggrecan (zeige ACAN Antikörper) degradation in cultured murine cartilage and surgically induced osteoarthritis in vivo following mechanical destabilization of the knee joint.
activation of astrocyte MMP2 (zeige MMP2 Antikörper)/JNK1 (zeige MAPK8 Antikörper)/2 contributes to the pathogenesis of pain hypersensitivity in the complex regional pain syndrome model
JNK1 (zeige MAPK8 Antikörper)/2-dependent regulation of p66ShcS36 phosphorylation, is reported.
This study demonstrated that the disruption of JNK2 appears to have a greater impact on tolerance than the other isoforms in the tail-flick but not the hot-plate test.
although JNK (zeige MAPK8 Antikörper) activation and RIP3 (zeige MPRIP Antikörper) expression are induced by FS, neither contributes to the liver injury.
morphine activated JNK2 through an arrestin-independent Src- and PKC-dependent mechanism, whereas fentanyl activated JNK2 through a Src-GRK3/arrestin-2-dependent and PKC-independent mechanism.
studies herein support that JNK2 inhibits cell differentiation in normal and cancer-derived mammary cells
this study indicates that JNK2 is a physiological kinase responsible for eNOS (zeige NOS3 Antikörper)-Ser (zeige SIGLEC1 Antikörper)(116) phosphorylation and regulates NO production.
Data show that proinflammatory cytokines induction was ERK1/2 and JNK1 (zeige MAPK8 Antikörper)/2 dependent.
These data suggest that the p38 (zeige MAPK14 Antikörper) and JNK (zeige MAPK8 Antikörper) signaling pathways play pivotal roles in PRRSV replication and may regulate immune responses during virus infection.
MPK9 and MPK12 (zeige MAPK12 Antikörper) are positive regulators of salicylic acid signaling in Arabidopsis guard cells.
MPK9 and MPK12 (zeige MAPK12 Antikörper) are key regulators mediating both abscisic acid (ABA) and Methyl jasmonate (MeJA) signalling in guard cells.
Data suggest that MPK9 is autoactivated via phosphorylation independent of any upstream MAPK (zeige MAPK1 Antikörper) kinase signaling; autophosphorylation occurs at both threonine and tyrosine residues in Thr (zeige TRH Antikörper)-Asp (zeige ASIP Antikörper)-Tyr (zeige TYR Antikörper) motif and in C-terminal regulatory extension.
MPK9 and MPK12 (zeige MAPK12 Antikörper) function redundantly downstream of extracellular reactive oxygen production and intracellular accumulation, cytosolic alkalisation and Ca(2 (zeige CA2 Antikörper)+)cytosolic oscillation in yeast elcictor-induced stomatal closure
MPK9 and MPK12 (zeige MAPK12 Antikörper) act downstream of ROS (zeige ROS1 Antikörper) and cytosolic Ca2 (zeige CA2 Antikörper)+ and upstream of anion channels in the guard cell abscisic acid signaling cascade.
MAP kinases MPK9 and MPK12 (zeige MAPK12 Antikörper) are preferentially expressed in guard cells and positively regulate ROS (zeige ROS1 Antikörper)-mediated ABA signaling.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
mitogen-activated protein kinase 9
, Jun kinase
, MAP kinase 9
, MAPK 9
, c-Jun N-terminal kinase 2
, c-Jun kinase 2
, stress-activated protein kinase 1a
, stress-activated protein kinase JNK2
, JNK/SAPK alpha
, mitogen activated protein kinase 9
, protein kinase, mitogen-activated 9
, stress activated protein kinase alpha II
, janus kinase 2
, c-JUN amino-terminal kinase-2 alpha1