anti-Schwein MAPK14 Antikörper für Immunohistochemistry (Frozen Sections)

Recommended MAPK14 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Mitogen-Activated Protein Kinase 14 (MAPK14) Antikörper
  • CSBP
  • CSBP1
  • CSBP2
  • CSPB1
  • EXIP
  • Mxi2
  • PRKM14
  • PRKM15
  • RK
  • SAPK2A
  • p38
  • p38ALPHA
  • CRK1
  • Csbp1
  • Csbp2
  • Exip
  • Hog
  • Prkm14
  • Prkm15
  • Sapk2A
  • p38Hog
  • p38alpha
  • 186F5S
  • BG:DS00797.3
  • CG7393
  • D-p38
  • D-p38 MAPK
  • D-p38b
  • Dm p38b
  • Dmel\\CG7393
  • Dmp38b
  • Dp38
  • Dp38b
  • ESTS:186F5S
  • Mpk34C
  • anon-sts23
  • dp38b
  • p38 MAPK
  • p38 beta
  • p38B
  • p38Kb
  • p38beta
  • Crk1
  • p38-alpha
  • p38MAPK
  • p38a
  • csbp
  • mapk14a
  • mxi2
  • sapk2
  • sapk2a
  • AP22.98
  • AP22_98
  • ATMPK14
  • mitogen-activated protein kinase 14
  • SAPK2a
  • MAP kinase 14A
  • MAP kinase p38a
  • MAPK 14A
  • MAPK14
  • fk28c03
  • hm:zeh1243
  • wu:fk28c03
  • zp38a
  • mitogen-activated protein kinase 14
  • mitogen activated protein kinase 14
  • p38b MAP kinase
  • mitogen-activated protein kinase 14 S homeolog
  • mitogen-activated protein kinase 14a
  • MAPK14
  • Mapk14
  • p38b
  • mapk14.S
  • MPK14
  • mapk14a
Epitop
AA 341-360
48
38
26
24
19
17
9
9
9
8
8
8
8
7
7
7
5
5
4
4
4
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Huhn, Rind (Kuh), Hund, Meerschweinchen, Hamster, Human, Affe, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf
317
136
133
23
16
16
13
10
10
9
7
7
4
4
3
3
2
1
1
1
Wirt
Kaninchen
260
61
2
2
Klonalität
Polyklonal
Konjugat
Dieser MAPK14 Antikörper ist unkonjugiert
13
11
8
8
8
8
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
303
141
107
59
35
35
16
16
9
6
3
2
2
1
1
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN5551337
$ 423.50
Zzgl. Versandkosten $45.00

General

Antigen Mitogen-Activated Protein Kinase 14 (MAPK14) Antikörper
Epitop AA 341-360
(48), (38), (26), (24), (19), (17), (9), (9), (9), (8), (8), (8), (8), (7), (7), (7), (5), (5), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Huhn, Rind (Kuh), Hund, Meerschweinchen, Hamster, Human, Affe, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf
(317), (136), (133), (23), (16), (16), (13), (10), (10), (9), (7), (7), (4), (4), (3), (3), (2), (1), (1), (1)
Wirt Kaninchen
(260), (61), (2), (2)
Klonalität
Polyklonal
Konjugat Dieser MAPK14 Antikörper ist unkonjugiert
(13), (11), (8), (8), (8), (8), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
(303), (141), (107), (59), (35), (35), (16), (16), (9), (6), (3), (2), (2), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-MAPK14 Antikörper

Target Details MAPK14 Anwendungsinformationen Handhabung Bilder
Spezifität Detects ~43 kDa corresponding to the molecular mass of p38 on SDS-PAGE immunoblots.
Reinigung Serum
Immunogen A 20 residue synthetic peptide based on the Human p38 (residues 341-360) with the Cysteine residue added and coupled to KLH
Isotyp IgG
Plasmids, Primers & others

Target Details MAPK14

Produktdetails anti-MAPK14 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung MAP Kinase p38 alpha / MAPK14 (MAPK14 Antibody Abstract)
Hintergrund The MAPK (mitogen activated protein kinase) comprises a family of ubiquitous praline-directed, protein-serine/threonine kinases which signal transduction pathways that control intracellular events including acute responses to hormones and major developmental changes in organisms (1). This super family consists of stress activated protein kinases (SAPKs), extracellular signal-regulated kinases (ERKs), and p38 kinases, each of which forms a separate pathway (2). The kinase members that populate each pathway are sequentially activated by phosphorylation. Upon activation, p38 MAPK/SAPK2α translocates into the nucleus where it phosphorylates one or more nuclear substrates, effecting transcriptional changes and other cellular processes involved in cell growth, division, differentiation, inflammation, and death (3). Specifically p38 always acts as a pro-apoptotic factor with its activation leading to the release of cytochrome c from mitochondria and cleavage of caspase 3 and its downstream effector, PARP (4). p38 MAPK is activated by a variety of chemical stress inducers including hydrogen peroxide, heavy metals, anisomycin, sodium salicylate, LPS, and biological stress signals such as tumor necrosis factor, interleukin-1, ionizing and UV irradiation, hyperosmotic stress and chemotherapeutic drugs (5). As a result, p38 alpha has been widely validated as a target for inflammatory disease including rheumatoid arthritis, COPD and psoriasis (6) and has also been implicated in cancer, CNS and diabetes (7).Synonyms: CSBP, CSBP1, CSBP2, CSPB1, Cytokine suppressive anti-inflammatory drug-binding protein, MAX-interacting protein 2, MXI2, Mitogen-activated protein kinase 14, SAPK2A, p38 alpha
Gen-ID 1432
NCBI Accession NP_001306
UniProt Q16539
Pathways MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagie, Thromboxane A2 Receptor Signaling

Anwendungsinformationen

Produktdetails anti-MAPK14 Antikörper Target Details MAPK14 Handhabung Bilder zurück nach oben
Applikations-hinweise Western blot: A 1/5000 dilution of this antibody was sufficient for detection of p38 in 20 μgof HeLa cell lysate by ECL Immunoblot analysis. Immunoprecipitation: 1/250. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-MAPK14 Antikörper Target Details MAPK14 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.