anti-Ratte (Rattus) CDC42 Antikörper für Immunohistochemistry (Frozen Sections)

Recommended CDC42 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) Antikörper
  • CDC42Hs
  • G25K
  • AI747189
  • AU018915
  • cdc42a
  • wu:fb07d08
  • wu:fj62g06
  • zgc:63918
  • Xcdc42
  • cdc42hs
  • g25k
  • CDC42
  • CG12530
  • Cdc42Dm
  • D-CDC42
  • D-Cdc42
  • D-cdc42
  • DCDC42
  • DCdc42
  • Dcdc42
  • Dm Cdc42
  • DmCDC42
  • Dmcdc42
  • Dmel\\CG12530
  • cdc42
  • cell division cycle 42
  • Cell division control protein 42 homolog
  • cell division control protein 42 homolog
  • cell division cycle 42 L homeolog
  • CG12530 gene product from transcript CG12530-RC
  • Rho family GTPase
  • CDC42
  • Cdc42
  • cdc42
  • LOC100636735
  • LOC100637699
  • LOC100638834
  • cdc42.L
Epitop
AA 121-138
15
13
13
10
10
8
6
5
5
4
4
3
2
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus), Rind (Kuh)
125
66
64
17
7
7
7
7
5
4
3
3
2
2
1
1
1
1
1
1
Wirt
110
12
7
Klonalität
Polyklonal
Konjugat
Dieser CDC42 Antikörper ist unkonjugiert
5
5
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
103
55
33
26
15
13
8
6
6
3
3
2
2
1
Optionen
Hersteller
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Produktnummer ABIN965836
$ 396.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1493926 ICC IHC IHC (fro) IHC (p) WB Rabbit AA 121-138 Anmelden zum Anzeigen Polyclonal 0
1 ABIN4889044 ELISA IHC (fro) WB Rabbit C-Term, Isoform 2 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) Antikörper
Epitop AA 121-138
(15), (13), (13), (10), (10), (8), (6), (5), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus), Rind (Kuh)
(125), (66), (64), (17), (7), (7), (7), (7), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Wirt
(110), (12), (7)
Klonalität
Polyklonal
Konjugat Dieser CDC42 Antikörper ist unkonjugiert
(5), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(103), (55), (33), (26), (15), (13), (8), (6), (6), (3), (3), (2), (2), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CDC42 Antikörper

Target Details CDC42 Anwendungsinformationen Handhabung Referenzen für anti-CDC42 Antikörper (ABIN965836) Bilder
Immunogen A synthetic peptide corresponding to a sequence at the middle region of human CDC42 (121-138aa), identical to the related mouse and rat sequence.
Plasmids, Primers & others

Target Details CDC42

Produktdetails anti-CDC42 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CDC42 Antikörper (ABIN965836) Bilder zurück nach oben
Antigen
Andere Bezeichnung CDC42 (CDC42 Antibody Abstract)
Hintergrund Cell division control protein 42 homolog also known as CDC42 is a protein involved in regulation of the cell cycle. In humans, CDC42 is encoded by the CDC42 gene.CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
Pathways MAPK Signalweg, Microtubule Dynamics, RTK Signalweg, WNT Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling

Anwendungsinformationen

Produktdetails anti-CDC42 Antikörper Target Details CDC42 Handhabung Referenzen für anti-CDC42 Antikörper (ABIN965836) Bilder zurück nach oben
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CDC42 Antikörper Target Details CDC42 Anwendungsinformationen Referenzen für anti-CDC42 Antikörper (ABIN965836) Bilder zurück nach oben
Rekonstitution 0.2ml of distilled water will yield a concentration of 500µg/ml.
Buffer Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Konservierungs-mittel Thimerosal (Merthiolate), Sodium azide
Lagerung -20 °C

Referenzen für anti-CDC42 Antikörper (ABIN965836)

Produktdetails anti-CDC42 Antikörper Target Details CDC42 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Shinjo, Koland, Hart, Narasimhan, Johnson, Evans, Cerione: "Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 24, pp. 9853-7, 1991

Munemitsu, Innis, Clark, McCormick, Ullrich, Polakis: "Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42." in: Molecular and cellular biology, Vol. 10, Issue 11, pp. 5977-82, 1990