anti-Human BAD Antikörper für Flow Cytometry

Recommended BAD Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
BCL2-Associated Agonist of Cell Death (BAD) Antikörper
  • bad
  • fa01b12
  • wu:fa01b12
  • wu:fa96d04
  • BAD
  • BBC2
  • BCL2L8
  • AI325008
  • Bbc2
  • BCL2-associated agonist of cell death b
  • BCL2 associated agonist of cell death
  • BCL2-associated agonist of cell death
  • badb
  • BAD
  • Bad
Epitop
AA 92-127
60
57
53
50
48
46
42
39
28
22
22
20
20
20
20
20
20
20
20
20
20
20
20
20
20
19
19
19
19
18
18
15
15
12
10
9
8
7
7
5
5
5
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus
782
447
276
19
15
8
5
4
3
2
2
1
1
1
1
1
1
Wirt
Kaninchen
997
50
2
1
Klonalität
Polyklonal
Konjugat
Dieser BAD Antikörper ist unkonjugiert
67
66
66
60
60
60
6
6
6
6
6
6
6
6
6
6
6
2
2
2
2
2
2
2
2
2
2
2
Applikation
Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
528
504
396
288
125
79
55
30
13
11
6
5
4
3
2
1
1
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN3030135
$ 411.13
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
14.1097355 ABIN5542486 ELISA FACS WB Mouse IgG1 AA 1-168, full length Anmelden zum Anzeigen 1G5B3
1 ABIN388118 FACS IHC (p) WB Rabbit Ig AA 92-127, BH3 Domain Anmelden zum Anzeigen Polyclonal 3
1 ABIN957139 IHC (fro) FACS IHC (p) IP WB Rabbit Anmelden zum Anzeigen Polyclonal
1 ABIN4881163 ELISA FACS WB Mouse IgG1 Anmelden zum Anzeigen 1G5B3
1 ABIN4902999 FACS ICC IHC IP WB Rabbit IgG Anmelden zum Anzeigen
1 ABIN1841063 FACS IHC (p) WB Rabbit AA 92-127 Anmelden zum Anzeigen Polyclonal
1 ABIN4282854 FACS WB Rabbit Anmelden zum Anzeigen Polyclonal
1 ABIN4282855 FACS WB Rabbit Anmelden zum Anzeigen Polyclonal
1 ABIN5624354 FACS Rabbit IgG1 kappa pSer112 Anmelden zum Anzeigen BADS112-B9
1 ABIN3059653 FACS IF/ICC IHC IP WB Rabbit Anmelden zum Anzeigen Polyclonal

General

Antigen BCL2-Associated Agonist of Cell Death (BAD) Antikörper
Epitop AA 92-127
(60), (57), (53), (50), (48), (46), (42), (39), (28), (22), (22), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (19), (19), (19), (19), (18), (18), (15), (15), (12), (10), (9), (8), (7), (7), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus
(782), (447), (276), (19), (15), (8), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(997), (50), (2), (1)
Klonalität
Polyklonal
Konjugat Dieser BAD Antikörper ist unkonjugiert
(67), (66), (66), (60), (60), (60), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(528), (504), (396), (288), (125), (79), (55), (30), (13), (11), (6), (5), (4), (3), (2), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-BAD Antikörper

Target Details BAD Anwendungsinformationen Handhabung Bilder
Reinigung Purified
Immunogen A portion of amino acids 92-127 from the human protein was used as the immunogen for this Bad antibody.
Isotyp Ig Fraction

Target Details BAD

Produktdetails anti-BAD Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Bad (BAD Antibody Abstract)
Hintergrund Apoptosis or programmed cell death is a physiological cellular process characterized by cell shrinkage, membrane blebbing, DNA fragmentation, and release of Cytochrome C from the mitochondria. It is utilized by the organism to get rid of unwanted cells, which is critical for normal development and homeostasis of an organism. Disregulation of normal apoptosis process have been implicated in a variety of diseases, including cancer, autoimmune diseases, viral infections, etc. Programmed cell death occurs through complex cascades of cell signaling in which Bcl-2 family members, among others, play an important role.The Bcl-2 family of proteins regulate apoptosis as well as execute death signals at the mitochondrion. Members of this family include both pro- and anti-apoptotic proteins that hare homology sequences called Bcl-2 Homology domains (BH1-4) which mediate dimmer formation. The BH3 proteins, such as BID, NOXA, PUMA, BIK, BIM and BAD are all pro-apoptotic and share sequence homology within the amphipathic alpha-helical BH3 region, which is required for their apoptotic function. They may trigger release of death-inducing molecules such as Cytochrome C, Smac, and endonuclease G. Anti-apoptotic family members, including Bcl-2 and Bcl-XL, play inhibitory roles. Bcl-2 family proteins may form homodimers or heterodimers between pro- and anti-apoptotic members, the ratios of which determine the cell fate.
UniProt Q92934
Forschungsgebiet Cancer, Apoptosis/Necrosis
Pathways MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, Apoptose, Fc-epsilon Rezeptor Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events

Anwendungsinformationen

Produktdetails anti-BAD Antikörper Target Details BAD Handhabung Bilder zurück nach oben
Applikationshinweise Titration of the Bad antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-BAD Antikörper Target Details BAD Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Aliquot the Bad antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Bilder

Produktdetails anti-BAD Antikörper Target Details BAD Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 92-127) antibody (ABIN3030135) Bad antibody flow cytometric analysis of HeLa cells (right histogram) compared to a n...
Immunohistochemistry (IHC) image for anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 92-127) antibody (ABIN3030135) IHC analysis of FFPE human hepatocarcinoma tissue stained with the Bad antibody
Western Blotting (WB) image for anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 92-127) antibody (ABIN3030135) Western blot analysis of Bad antibody and mouse bladder tissue lysate