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Human Polyclonal FAF1 Primary Antibody für IHC, ELISA - ABIN1002283
Ryu, Kim: Apoptosis induced by human Fas-associated factor 1, hFAF1, requires its ubiquitin homologous domain, but not the Fas-binding domain. in Biochemical and biophysical research communications 2001
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Human Polyclonal FAF1 Primary Antibody für WB - ABIN966117
Park, Jang, Lee, Lee, Kim: Fas-associated factor-1 inhibits nuclear factor-kappaB (NF-kappaB) activity by interfering with nuclear translocation of the RelA (p65) subunit of NF-kappaB. in The Journal of biological chemistry 2004
Show all 2 Pubmed References
Human Polyclonal FAF1 Primary Antibody für ELISA, WB - ABIN564825
Baron, Pedrioli, Tyagi, Johnson, Wood, Fountaine, Wightman, Alexandru: VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase. in BMC biology 2014
Human Polyclonal FAF1 Primary Antibody für IP, IHC - ABIN223070
Altomare, Menges, Pei, Zhang, Skele-Stump, Carbone, Kane, Testa: Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice. in Proceedings of the National Academy of Sciences of the United States of America 2009
This study reveals clear genetic-statistical evidence for a link of KRT8 (zeige KRT8 Antikörper), FAF1 and PTH1R (zeige PTH1R Antikörper) with some of leg weakness related traits in pigs.
Helicobacter pylori, a risk factor for gastric cancer, down-regulated FAF1 expression via NF-kappaB (zeige NFKB1 Antikörper) signaling in gastric carcinoma cells, promoting tumor growth.
Knockdown of FAF1 suppressed Sanguinarine (SNG)-induced inhibition of cell proliferation, invasion, and migration and induction of cell cycle arrest and apoptosis in NSCLC cells. SNG also inhibited implanted tumor growth and increased FAF1 expression in tumors in vivo.
These data demonstrate the presence of an FAF1-PARP1 (zeige PARP1 Antikörper) axis that is involved in oxidative stress-induced (zeige SQSTM1 Antikörper) necrosis and in the pathology of Parkinson's disease.
FAF1 physically interacts with XIAP (zeige XIAP Antikörper). FAF1 attenuates XIAP (zeige XIAP Antikörper)-mediated NF-kappaB (zeige NFKB1 Antikörper) activation.
confirmation of the association between rs17106184 (FAF1) and Type 2 Diabetes in a northern Han Chinese population
FAF1 plays a novel role in negatively regulating virus-induced IFN-beta (zeige IFNB1 Antikörper) production and the antiviral response by inhibiting the translocation of active, phosphorylated IRF3 (zeige IRF3 Antikörper) from the cytosol to the nucleus
Progression of the DNA replication fork is coordinated by FAF1. FAF1 binds to the licensing factor CDT-1 (zeige CDT1 Antikörper) and additional ubiquitylated proteins, thus promoting CDC48 (zeige vcp Antikörper)-dependent turnover and disassembly of DNA replication factor (zeige CDT1 Antikörper) complexes.
Report a novel role for FAF1 in regulating CD40-induced NFkappaB activation via a negative feedback loop.
The repertoire of VAPB (zeige VAPB Antikörper) interactors is more diverse than previously anticipated and link VAPB (zeige VAPB Antikörper) to the function of ATPase (zeige DNAH8 Antikörper) complexes such as p97 (zeige EIF4G2 Antikörper)/FAF1 and ASNA1 (zeige ASNA1 Antikörper)/transmembrane-domain recognition complex.
long-chain unsaturated fatty acids also induced polymerization of Fas-associated factor 1 (FAF1), the only other mammalian protein that contains a UAS domain homologous to that of Ubxd8 (zeige FAF2 Antikörper)
FAF1 knockdown immune cells were highly susceptible to RNA virus infection and showed low levels of inflammatory cytokines and type I interferon (zeige IFNA Antikörper) (IFN) production.
Increased FAF1 expression triggers caspase-3 (zeige CASP3 Antikörper) cleavage and activation, leading to hyperphosphorylated tau aggregation and subsequent neurofibrillary tangles formation, in turn initiating apoptosis.
Taken together, these results suggest a new role for FAF1: that of a positive modulator for Parkinson's disease .
FAF1 is a novel inhibitory factor of canonical Wnt (zeige WNT2 Antikörper) signaling pathway
Capsaicin-induced cancer cell apoptosis involves FAF1, a TRPV1 (zeige TRPV1 Antikörper) associated protein.
Analysis of FAF1 expression revealed that the protein is present in early preimplantation stages, while embryonic expression of Faf1 mRNA becomes appreciable at 4-cell stage.
Data show that Faf1 protein level is down-regulated during apoptosis in a caspase-3 (zeige CASP3 Antikörper)- and Apaf1 (zeige APAF1 Antikörper)-dependent manner.
analysis of the negative feedback regulation of Aurora-A (zeige AURKA Antikörper) via phosphorylation of Fas-associated factor-1
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.
Fas (TNFRSF6) associated factor 1
, FAS-associated factor 1
, FAS-associated factor 1-like
, TNFRSF6-associated factor 1
, UBX domain protein 3A
, UBX domain-containing protein 12
, UBX domain-containing protein 3A