Produkt kostenlos erhalten?
Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validierenRelevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
---|---|---|---|---|---|---|---|---|---|---|
1 | ABIN798716 | WB | Rabbit | N-Term | Anmelden zum Anzeigen | Polyclonal | 0 | |||
1 | ABIN797253 | WB | Rabbit | IgG | AA 50-95 | Anmelden zum Anzeigen | Polyclonal | 0 | ||
1 | ABIN2628907 | WB | Rabbit | IgG | AA 15-30 | Anmelden zum Anzeigen | Polyclonal | 0 | ||
1 | ABIN354139 | IHC WB | Sheep | AA 6-21 | Anmelden zum Anzeigen | Polyclonal | 0 | |||
1 | ABIN354138 | IHC WB | Rabbit | AA 6-21 | Anmelden zum Anzeigen | Polyclonal | 0 |
General |
|
---|---|
Antigen | SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) Antikörper |
Epitop | N-Term Alternativen |
Reaktivität | Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus) Alternativen |
Wirt | Kaninchen Alternativen |
Klonalität | |
Konjugat | Unkonjugiert Alternativen |
Applikation |
Western Blotting (WB)
Alternativen
|
Hersteller | Anmelden zum Anzeigen |
ProduktdetailsAntigendetails Anwendungsinformationen Handhabung Bilder |
|
Blocking Peptide | Zu diesem Produkt passt das Blocking Peptide ABIN984626. |
Sequenz | DQEAKPSTED LGDKKEGEYI KLKVIGQDSS EIHFKVKMTT HLKKLKESYC |
Homologie | Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100% |
Produktmerkmale | This is a rabbit polyclonal antibody against Sumo1. It was validated on Western Blot. |
Reinigung | Affinity Purified |
AntigendetailsProduktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben |
|
Antigen | |
Andere Bezeichnung | Sumo1 (SUMO1 Antibody Abstract) |
Hintergrund |
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. It is involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. It may also regulate a network of genes involved in palate development. Alias Symbols: GMP1, MGC103203, PIC1, SENTRIN, SMT3, SMT3H3, SMTP3, SUMO-1, Smt3C, Ubl1 Protein Interaction Partner: Pten, Stat1, Pml, Casp8ap2, Traf3, Pik3c3, Npm1, Mdm2, Ube2i, Trp53, Rangap1, Ranbp2, Mthfs, Sox2, Senp2, Rbbp7, Slc1a2, Uimc1, Nfatc2ip, Irf1, Irf8, Smad4, BCL11A, AXIN1, Myb, Pax6, Sept2, Daxx, Sf1, Sp3, Pou5f1, Hif1a, Nfkb2, Junb, Jun, Protein Size: 101 |
Molekulargewicht | 11 kDa |
Gen-ID | 22218 |
NCBI Accession | NM_009460, NP_033486 |
UniProt | P63166 |
Pathways | M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus |
AnwendungsinformationenProduktdetails Antigendetails Handhabung Bilder zurück nach oben |
|
Applikationshinweise | Optimal working dilutions should be determined experimentally by the investigator. |
Kommentare |
Antigen size: 101 AA |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben |
|
Format | Liquid |
Konzentration | Lot specific |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
Konservierungsmittel | Sodium azide |
Vorsichtsmaßnahmen | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handhabung | Avoid repeated freeze-thaw cycles. |
Lagerung | -20 °C |
Informationen zur Lagerung | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
BilderProduktdetails Antigendetails Anwendungsinformationen Handhabung zurück nach oben |
|
Bilder des Herstellers |