anti-Ratte (Rattus) Dynactin 1 Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended Dynactin 1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Dynactin 1 (DCTN1) Antikörper
  • DAP-150
  • DP-150
  • P135
  • Chip150
  • DCTN1
  • DKFZp469C1813
  • AL022633
  • Glued
  • p150
  • p150
  • CG9206
  • DYNA_DROME
  • Dmel\\CG9206
  • FCP-D
  • Glu
  • P150
  • P150[Glued]
  • p150/Glued
  • p150/glued
  • p150[Glued]
  • p150[glued]
  • t1
  • Dynactin-1
  • glued
  • dynactin subunit 1
  • dynactin 1
  • Dynactin 1, p150 subunit
  • dynactin subunit 1 L homeolog
  • DCTN1
  • Dctn1
  • DCTN1-p150
  • dctn1.L
Reaktivität
Human, Maus, Ratte (Rattus)
79
48
42
6
6
5
4
3
2
2
2
2
1
1
1
Wirt
Kaninchen
49
19
9
5
Klonalität
Polyklonal
Konjugat
Dieser Dynactin 1 Antikörper ist konjugiert mit Cy5.5
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
67
24
21
16
12
12
8
8
2
2
1
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Produktnummer ABIN721500
$ 405.90
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN893648 IF (p) Alexa Fluor 555 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN721501 IF (p) Cy7 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN721498 IF (p) Cy3 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN721499 IF (p) Cy5 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN721502 IF (p) FITC Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN893649 IF (p) Alexa Fluor 488 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN893645 IF (p) Alexa Fluor 647 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN893647 IF (p) Alexa Fluor 350 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN2812280 IF (p) Alexa Fluor 594 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN721495 IF (p) IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN5001077 IF (p) Alexa Fluor 750 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN5001076 IF (p) Alexa Fluor 680 Rabbit IgG Anmelden zum Anzeigen Polyclonal 0

General

Antigen Dynactin 1 (DCTN1) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(79), (48), (42), (6), (6), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1)
Wirt Kaninchen
(49), (19), (9), (5)
Klonalität
Polyklonal
Konjugat Dieser Dynactin 1 Antikörper ist konjugiert mit Cy5.5
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p))
(67), (24), (21), (16), (12), (12), (8), (8), (2), (2), (1), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Dynactin 1 Antikörper

Target Details Dynactin 1 Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human DCTN1/Dynactin 1
Isotyp IgG

Target Details Dynactin 1

Produktdetails anti-Dynactin 1 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Dctn1 (DCTN1 Antibody Abstract)
Hintergrund

Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.Tissue specificity, Brain.Involvement in disease, Defects in DCTN1 are the cause of distal hereditary motor neuronopathy type 7B (HMN7B), also known as progressive lower motor neuron disease (PLMND). HMN7B is a neuromuscular disorder. Distal hereditary motor neuronopathies constitute a heterogeneous group of neuromuscular disorders caused by selective degeneration of motor neurons in the anterior horn of the spinal cord, without sensory deficit in the posterior horn. The overall clinical picture consists of a classical distal muscular atrophy syndrome in the legs without clinical sensory loss. The disease starts with weakness and wasting of distal muscles of the anterior tibial and peroneal compartments of the legs. Later on, weakness and atrophy may expand to the proximal muscles of the lower limbs and/or to the distal upper limbs.Defects in DCTN1 are a cause of susceptibility to amyotrophic lateral sclerosis (ALS). ALS is a neurodegenerative disorder affecting upper and lower motor neurons, and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology is likely to be multifactorial, involving both genetic and environmental factors.Defects in DCTN1 are the cause of Perry syndrome (PERRYS), also called parkinsonism with alveolar hypoventilation and mental depression. Perry syndrome is a neuropsychiatric disorder characterized by mental depression not responsive to antidepressant drugs or electroconvulsive therapy, sleep disturbances, exhaustion and marked weight loss. Parkinsonism develops later and respiratory failure occurred terminally.

Synonyms: Alternative names150 kDa dynein associated polypeptide, 150 kDa dynein-associated polypeptide, DAP 150, DAP-150, DAP150, DCTN 1, DCTN1, DCTN1_HUMAN, DP 150, DP-150, DP150, Dynactin 1 p150 Glued Drosophila homolog, Dynactin 1 p150 glued homolog Drosophila, Dynactin 1, Dynactin subunit 1, Dynactin1, HMN7B, P135, p150 Glued Drosophila homolog, p150 glued, p150 glued homolog, p150GLUED DROSOPHILA HOMOLOG OF, p150-glued, p150glued.

Gen-ID 1639
Pathways M Phase, ER-Nucleus Signaling

Anwendungsinformationen

Produktdetails anti-Dynactin 1 Antikörper Target Details Dynactin 1 Handhabung Bilder zurück nach oben
Applikationshinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Dynactin 1 Antikörper Target Details Dynactin 1 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months