Produkt kostenlos erhalten?
Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validierenRelevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
---|---|---|---|---|---|---|---|---|---|---|
1 | ABIN1700243 | IHC (p) WB | Biotin | Rabbit | IgG | Anmelden zum Anzeigen | Polyclonal | 0 | ||
1 | ABIN1713745 | IF (p) IHC (p) WB | Rabbit | IgG | Anmelden zum Anzeigen | Polyclonal | 0 |
General |
|
---|---|
Antigen | Centrosomal Protein 57kDa (CEP57) Antikörper |
Reaktivität | Human, Maus, Ratte (Rattus) Alternativen |
Wirt | Kaninchen Alternativen |
Klonalität | |
Konjugat | Dieser CEP57 Antikörper ist konjugiert mit HRP Alternativen |
Applikation |
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternativen
|
Hersteller | Anmelden zum Anzeigen |
Produktdetails anti-CEP57 AntikörperTarget Details CEP57 Anwendungsinformationen Handhabung Bilder |
|
Reinigung | Purified by Protein A. |
Immunogen | KLH conjugated synthetic peptide derived from human CEP57 |
Isotyp | IgG |
Target Details CEP57Produktdetails anti-CEP57 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben |
|
Antigen | |
Andere Bezeichnung | Cep57 (CEP57 Antibody Abstract) |
Hintergrund |
CEP57 (centrosomal protein 57 kDa), also known as PIG8, TSP57 or Translokin, is a 500 amino acid protein that localizes to both the nucleus and the cytoplasm, specifically associating with microtubules at the centrosome. Expressed ubiquitously, CEP57 exists as a homodimer that functions to mediate the mitogenic activity and nuclear translocation of FGF-2, an internalized growth factor, thereby regulating FGF-2 signaling pathways. Additionally, CEP57 is thought to play a role in spermatogenesis, possibly via the indirect regulation of gene expression. Human CEP57 shares 88 % sequence identity with its mouse and bovine orthologs, suggesting a highly conserved role between species. Multiple isoforms of CEP57 exist due to alternative splicing events. Synonyms: Centrosomal protein 57 kDa, Centrosomal protein of 57 kDa, Cep57, Cep57 protein, CEP57_HUMAN, FGF2 interacting protein, FGF2-interacting protein, KIAA0092, MVA2, PIG8, proliferation inducing protein 8, Testis specic protein 57, Testis-specic protein 57, Translokin, TSP57. |
Pathways | M Phase, Maintenance of Protein Location, Protein targeting to Nucleus, Growth Factor Binding |
AnwendungsinformationenProduktdetails anti-CEP57 Antikörper Target Details CEP57 Handhabung Bilder zurück nach oben |
|
Applikationshinweise |
WB 1:100-1000 IHC-P 1:100-500 |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails anti-CEP57 Antikörper Target Details CEP57 Anwendungsinformationen Bilder zurück nach oben |
|
Format | Liquid |
Konzentration | 1 μg/μL |
Buffer | Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin. |
Konservierungsmittel | Gentamicin sulfate |
Vorsichtsmaßnahmen | This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handhabung | Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase. |
Lagerung | 4 °C |
Informationen zur Lagerung | Store at 4°C |
Haltbarkeit | 12 months |