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anti-Human AKAP9 Antikörper:
anti-Mouse (Murine) AKAP9 Antikörper:
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Human Monoclonal AKAP9 Primary Antibody für IF, WB - ABIN968571
Lin, Wyszynski, Madhavan, Sealock, Kim, Sheng: Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1998
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Human Polyclonal AKAP9 Primary Antibody für IHC, ELISA - ABIN250389
Christian, Szaszák, Friedl, Drewianka, Lorenz, Goncalves, Furkert, Vargas, Schmieder, Götz, Zühlke, Moutty, Göttert, Joshi, Reif, Haase, Morano, Grossmann, Klukovits, Verli, Gáspár, Noack, Bergmann et al.: Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes. ... in The Journal of biological chemistry 2011
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Human Polyclonal AKAP9 Primary Antibody für ICC, IF - ABIN4278930
Oldenburger, Poppinga, Kos, de Bruin, Rijks, Heijink, Timens, Meurs, Maarsingh, Schmidt: A-kinase anchoring proteins contribute to loss of E-cadherin and bronchial epithelial barrier by cigarette smoke. in American journal of physiology. Cell physiology 2014
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Human Monoclonal AKAP9 Primary Antibody für ICC, IF - ABIN261462
Gorshkov, Mehta, Ramamurthy, Ronnett, Zhou, Zhang: AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons. in Nature chemical biology 2017
Dog (Canine) Polyclonal AKAP9 Primary Antibody für ELISA - ABIN4252975
Frank, Wiestler, Kropp, Hemminki, Spurdle, Sutter, Wappenschmidt, Chen, Beesley, Hopper, Meindl, Kiechle, Slanger, Bugert, Schmutzler, Bartram, Flesch-Janys, Mutschelknauss, Ashton, Salazar, Webb et al.: Association of a common AKAP9 variant with breast cancer risk: a collaborative analysis. ... in Journal of the National Cancer Institute 2008
Data suggest that CDK5RAP2 and CEP170 both interact with microtubule nucleation-promoting region of AKAP350A; CEP68 interacts with distal C-terminal region of AKAP350A; AKAP350A spans the bridge between centrioles. (CDK5RAP2 = CDK5 regulatory subunit associated protein 2; CEP170 = centrosomal protein 170kDa; AKAP350A = A kinase (PRKA) anchor protein (yotiao) 9; CEP68 = centrosomal protein 68kDa)
Findings suggest MALAT1 increases AKAP-9 expression by promoting SRPK1 (zeige SRPK1 Antikörper)-catalyzed SRSF1 (zeige SRSF1 Antikörper) phosphorylation in CRC (zeige CALR Antikörper) cells. These results reveal a novel molecular mechanism by which MALAT1 regulates AKAP-9 expression in CRC (zeige CALR Antikörper) cells.
AKAP9 gene harbors not only somatic frameshift mutations but also mutational ITH.
results support a model in which AKAP350 recruits CIP4 to the centrosome, providing a centrosomal scaffold to integrate microtubule and actin dynamics, thus enabling centrosome polarization and ensuring cell migration directionality.
Study suggests a role of rare missense variants at NRXN1 (zeige NRXN1 Antikörper) and AKAP9 in schizophrenia susceptibility, probably related to alteration of the excitatory/inhibitory synaptic balance, deserving further investigation
This study demonstrated that two rare AKAP9 variants( rs144662445 and rs149979685) are associated with Alzheimer's disease in African Americans.
AKAP9 has been identified as a Long QT Syndrome Type 1 modifying gene
data indicate that MALAT1 may promote CRC (zeige CALR Antikörper) tumor development via its target protein AKAP-9
A590T mutation in KCNQ1 (zeige KCNQ1 Antikörper) C-terminal helix D decreases KCNE1 (zeige KCNE1 Antikörper) channel trafficking and function but not Yotiao interaction.
AKAP (zeige AKAP1 Antikörper) proteins, most likely AKAP9, maintain the bronchial epithelial barrier by regulating the E-cadherin (zeige CDH1 Antikörper) expression at the cell membrane.
AKAP9 and, by inference, the regulation of the microtubule network are critical for blood-testis barrier function and subsequent germ cell development during spermatogenesis
AKAP9 is dispensable for T cell priming and migration into tissues and lymph nodes, but is required for T cell retention in tissues.
We postulate that this novel interaction linking MVI with the PKA pathway could be important for targeting AKAP9-PKA complex within cells and/or providing PKA to phosphorylate MVI tail domain.
Overexpression of an AKAP450 fragment containing the CK1delta-binding site inhibits Golgi-derived microtubule nucleation, Golgi distribution of intraflagellar transport protein 20 homologue, and ciliogenesis.
Mutations in Akap9 disrupt Sertoli cell maturation, gap and tight junctions and localization of zona occluden-1 and connexin43 (zeige GJA1 Antikörper).
in heart, Yotiao brings together PKA, PP1 (zeige PPP1CC Antikörper), PDE4D3, AC9 (zeige ADCY9 Antikörper), and the I(Ks) channel to achieve localized temporal regulation of beta-adrenergic stimulation.
Expression of Akap9 in the mouse striatum is modulated by a sequence variant (B2 SINE indel) in the 3' UTR (zeige UTS2R Antikörper) of Comt (catechol-O-methyltransferase (zeige COMT Antikörper)).
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3.
A-kinase anchor protein 350 kDa
, A-kinase anchor protein 450 kDa
, A-kinase anchor protein 9
, AKAP 120-like protein
, AKAP9-BRAF fusion protein
, centrosome- and Golgi-localized PKN-associated protein
, kinase N-associated protein
, protein hyperion
, protein kinase A anchoring protein 9
, protein phosphatase 1, regulatory subunit 45
, protein yotiao
, protein kinase A-anchoring protein 9
, GABA-B receptor-interacting scaffolding protein
, hyperion protein, 419 kD isoform
, A kinase (PRKA) anchor protein (yotiao) 9
, a-kinase anchor protein 9
, a-kinase anchor protein 9-like
, A kinase (PRKA) anchor protein 9
, A-kinase anchoring protein AKAP120
, A-kinase anchor protein 120 kDa
, AKAP 120
, myocyte A kinase anchor protein