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Mouse (Murine) Polyclonal SAR1B Primary Antibody für ELISA, WB - ABIN451619
Evans, Burdge, Wootton, Collins, Clark, Tan, Karpe, Frayn: Tissue-specific stable isotope measurements of postprandial lipid metabolism in familial combined hyperlipidaemia. in Atherosclerosis 2008
Human Polyclonal SAR1B Primary Antibody für ICC, IF - ABIN442685
Sané, Seidman, Spahis, Lamantia, Garofalo, Montoudis, Marcil, Levy: New Insights In Intestinal Sar1B GTPase Regulation and Role in Cholesterol Homeostasis. in Journal of cellular biochemistry 2015
Data suggest the importance of small Sar1b GTPase (zeige RACGAP1 Antikörper) (Sar1b) in organs involved in lipid transport and/or calcium trafficking such as the liver, intestine, skeletal muscle and heart.
Report compensatory Sar1a (zeige SAR1A Antikörper) elevation after Sar1b gene deletion in Caco-2/15 cells prevents chylomicron collapse.
SAR1B polymorphisms were associated with Alzheimer's disease (AD) risk; results were not significant after correction for multiple tests. Simultaneous screening using SAR1B rs11948613 and ApoE (zeige APOE Antikörper) epsilon4 status offered a better sensitivity for AD screening.
Our data also suggest that Sar1B overexpression contributes to regulation of CHOL transport and metabolism by facilitating rapid uptake and transport of CHOL.
although Sar1A (zeige SAR1A Antikörper) antagonizes the lipoprotein secretion-promoting activity of Sar1B, both isoforms modulate the expression of genes encoding cholesterol biosynthetic enzymes and the synthesis of cholesterol de novo.
the behavior of the human of Sar1A (zeige SAR1A Antikörper) and Sar1B, a key component of the COPII family of vesicle coat proteins, was examined.
Sar1b expression may promote intestinal lipid transport with the involvement of the coat protein (zeige GOLPH3 Antikörper) complex II network and the processing of SREBP-1c (zeige SREBF1 Antikörper).
Variable phenotypic expression of chylomicron retention disease in a kindred carrying a mutation of the Sara2 gene.
identify eight mutations in SARA2 that are associated with three severe disorders of fat malabsorption
Sara2 is an important gene in processes involving erythroid cell proliferation and differentiation.
Five mutations in the SAR1B gene causing Anderson disease.
The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
SAR1 gene homolog B
, GTP-binding protein SAR1b
, SAR1 homolog B
, hypothetical protein
, GTP-binding protein sar1b
, SAR1a gene homolog 2
, SAR1b gene homolog
, GTP-binding protein B
, GTP-binding protein Sara