Low Density Lipoprotein Receptor Produkte
(Low Density Lipoprotein Receptor (LDLR))
Kategorien
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010].
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Ausgewählte Low Density Lipoprotein Receptor Kategorien
Low Density Lipoprotein Receptor Antikörper
High quality antibodies with extensive validation data.
Low Density Lipoprotein Receptor ELISA Kits
Reliable ELISA kits for a wide range of species.
Low Density Lipoprotein Receptor Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Low Density Lipoprotein Receptor Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS, IHC, ICC
Validierungen
- (5)
Kat. Nr.
ABIN5542334
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN7268296
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Hamster, Human, Mouse, Plant, Rat
Applikation
WB, ELISA, FACS, IF (p), IHC (p)
Validierungen
- (5)
- (3)
Kat. Nr.
ABIN672111
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Low Density Lipoprotein Receptor ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6957532
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968344
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968345
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Low Density Lipoprotein Receptor Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Cynomolgus
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275138
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275139
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1309277
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Low Density Lipoprotein Receptor Produkten
: "VEGF-B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content." in: EMBO reports, Vol. 21, Issue 7, pp. e49343, (2020) (PubMed).: "Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained." in: The Journal of biological chemistry, Vol. 293, Issue 19, pp. 7329-7343, (2019) (PubMed).
: "Development of Novel DNA-Encoded PCSK9 Monoclonal Antibodies as Lipid-Lowering Therapeutics." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 27, Issue 1, pp. 188-199, (2019) (PubMed).
: "Clinical relevance of cholesterol homeostasis genes in colorectal cancer." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 10, pp. 1314-1327, (2019) (PubMed).
: "Besnoitia besnoiti infection alters both endogenous cholesterol de novo synthesis and exogenous LDL uptake in host endothelial cells." in: Scientific reports, Vol. 9, Issue 1, pp. 6650, (2019) (PubMed).
: "Global inactivation of carboxylesterase 1 (Ces1/Ces1g) protects against atherosclerosis in Ldlr-/-mice." in: Scientific reports, Vol. 7, Issue 1, pp. 17845, (2018) (PubMed).
: "The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins." in: Molecular metabolism, Vol. 16, pp. 88-99, (2018) (PubMed).
: "Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex." in: Scientific reports, Vol. 8, Issue 1, pp. 16845, (2018) (PubMed).
: "Differential Response of B Cells to an Immunogen, a Mitogen and a Chemical Carcinogen in a Mouse Model System" in: Asian Pacific journal of cancer prevention : APJCP, Vol. 19, Issue 1, pp. 81-90, (2018) (PubMed).
: "27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells." in: Neurotoxicology, Vol. 59, pp. 88-97, (2017) (PubMed).
Synonyme und alternative Namen zu Low Density Lipoprotein Receptor
low density lipoprotein receptor (LDLR), low density lipoprotein receptor (Ldlr), low density lipoprotein receptor a (ldlra), low density lipoprotein receptor S homeolog (ldlr.S), low density lipoprotein receptor L homeolog (ldlr.L), FH, FHC, fhc, Hlb301, LDLA, LDLCQ2, ldlcq2, ldlr, ldlr-a, ldlr-b, ldlr2-a, LDLRA, LDL receptor-2, LDL receptor 1Bezeichner auf Proteinebene für Low Density Lipoprotein Receptor
- LDL receptor
- low-density lipoprotein receptor
- low-density lipoprotein receptor class A domain-containing protein 3
- low density lipoprotein receptor (familial hypercholesterolemia)
- LDL receptor 2
- low density lipoprotein receptor-2
- low-density lipoprotein receptor 2
- LDL receptor-1
- low-density lipoprotein receptor 1
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