anti-Human SERPING1 Antikörper für Radial Immunodiffusion

Recommended SERPING1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1) Antikörper
  • fb64f02
  • im:7159527
  • si:dkeyp-110g5.2
  • wu:fb60c09
  • wu:fb62a08
  • wu:fb64f02
  • LOC100136072
  • C1-INH
  • C1INH
  • C1nh
  • C1IN
  • C1NH
  • HAE1
  • HAE2
  • serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
  • C1 inhibitor
  • serpin family G member 1
  • serine (or cysteine) peptidase inhibitor, clade G, member 1
  • serping1
  • LOC100136072
  • SERPING1
  • Serping1
Reaktivität
Human
155
34
27
7
5
5
2
Wirt
Ziege
94
56
21
18
2
Klonalität
Polyklonal
Konjugat
Dieser SERPING1 Antikörper ist unkonjugiert
17
14
7
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunodiffusion (ID), Immunoelectrophoresis (IEP), Radial Immunodiffusion (RID)
114
86
64
26
25
18
10
8
6
5
4
4
2
2
1
1
1
1
1
1
Optionen
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Produktnummer ABIN457963
$ 257.19
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN458102 ID IEP RID Rabbit IgG Anmelden zum Anzeigen Polyclonal 0

General

Antigen Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1) Antikörper
Reaktivität Human
(155), (34), (27), (7), (5), (5), (2)
Wirt Ziege
(94), (56), (21), (18), (2)
Klonalität
Polyklonal
Konjugat Dieser SERPING1 Antikörper ist unkonjugiert
(17), (14), (7), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunodiffusion (ID), Immunoelectrophoresis (IEP), Radial Immunodiffusion (RID)
(114), (86), (64), (26), (25), (18), (10), (8), (6), (5), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1)
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Produktdetails anti-SERPING1 Antikörper

Target Details SERPING1 Anwendungsinformationen Handhabung Bilder
Spezifität The antiserum does not cross react with any other component of human plasma. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. of this antiserum has not been tested in detail.
Produktmerkmale Precipitating polyclonal goat antiserum to human C1 esterase inhibitor
Reinigung Adsorption: Immunoaffinity adsorbed using insolubilized antigens as required, to eliminate antibodies reacting with other plasma proteins. The use of insolubilized adsorption antigens prevents the presence of excess adsorbent protein or immune complexes in the antiserum.
Immunogen C1 esterase inhibitor is a single chain acid glycoprotein with a molecular weight of 110,000. The protein has a high carbohydrate content. In immunoelectrophoresis it ha an alpha mobility. The concentration in normal serum ranges from 150 to 350 µ g/ml. Reduced levels are observed in hereditary angioedema. It regulates the activation of complement factor C1 as well as the activity of activated C1 by coupling with the active catalytic site at the light chains of C1r and C1s. Moreover it also inhibits, kallikrein, Factor XI and Factor XII. Freund’s complete adjuvant is used in the first step of the immunization procedure.
Isotyp IgG

Target Details SERPING1

Produktdetails anti-SERPING1 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung C1 Esterase Inhibitor (SERPING1 Antibody Abstract)
Hintergrund The reactivity of the antiserum is restricted to C1 esterase inhibitor. In immunoelectrophoresis and radial immunodiffusion (Ouchterlony), using various antiserum concentrations against fresh normal human plasma a single precipitin line is obtained which shows a reaction of identity with the precipitin line obtained with purified C1 esterase inhibitor. No reaction is obtained with any other plasma protein component or serum. However, the antiserum may also react with fibrin monomers, circulating fibrinopeptides and fibrin degradation products
Pathways Komplementsystem

Anwendungsinformationen

Produktdetails anti-SERPING1 Antikörper Target Details SERPING1 Handhabung Bilder zurück nach oben
Applikations-hinweise In precipitating techniques as immunoelectrophoresis and single or double radial immunodiffusion to identify the presence of C1 esterase inhibitor in human plasma or other body fluids or to determine its concentration. The presence of non-precipitating antibodies has not been assayed. This does not exclude the use of the antiserum in non-precipitating antibody-binding techniques if proper controls are included. In immunoelectrophoresis use 2 µ l or equivalent against 120 µ l antiserum. In double radial immunodiffusion (Ouchterlony) use a rosette arrangement with 10 µ l in a 3 mm diameter center well and 2 µ l serum samples (neat and serially diluted) in 2 mm diameter peripheral wells.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-SERPING1 Antikörper Target Details SERPING1 Anwendungsinformationen Bilder zurück nach oben
Format Lyophilized
Konzentration Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal goat serum. No foreign proteins added. Antibody titre: Precipitin titre 1:32 when tested against pooled normal human plasma in agar-block immunodiffusion titrat
Buffer Delipidated, heat inactivated, lyophilized, stable whole antiserum
Konservierungs-mittel Without preservative
Lagerung 4 °C