Coagulation Factor XII (Hageman Factor) ELISA Kit

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F12 ELISA Kit
$530.53
96 tests
Human
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F12 ELISA Kit
$545.68
96 tests
Mouse (Murine)
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F12 ELISA Kit
$638.00
96 tests
Rat (Rattus)
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F12 ELISA Kit
$707.14
96 tests
Rabbit
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  • Experiment Reproducibility
    The results will be likely more reproducible, with high inter- or intra-assay CV and Recovery (for values within the std curve) than the available alternatives.
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    The recommended assay will likely function better with approved sample types, and will not suffer from undue matrix interference than the available alternatives.
Picking recommended ELISA Kits will save you time - yet all 54 products covered by our Money Back Guarantee!
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F12 Antigen Profile

Beschreibung des Gens

This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged.

Alternative names and synonyms associated with F12

  • coagulation factor XII (F12) ELISA Kit
  • coagulation factor XII (Hageman factor) (F12) ELISA Kit
  • HAE3 ELISA Kit
  • HAEX ELISA Kit
  • HAF ELISA Kit
  • FXII ELISA Kit

Bezeichner auf Proteinebene für F12

Hageman factor , beta-factor XIIa part 1 , beta-factor XIIa part 2 , coagulation factor XII , coagulation factor XIIa heavy chain , coagulation factor XIIa light chain , factor XII , hageman factor , HAF

GENE ID SPEZIES
2161 Homo sapiens
306761 Rattus norvegicus
58992 Mus musculus
100351481 Oryctolagus cuniculus
100728720 Cavia porcellus
397474 Sus scrofa
280789 Bos taurus
489090 Canis lupus familiaris
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