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TFF1 ELISA Kit

TFF1 Reaktivität: Maus AA 22-87 Colorimetric Sandwich ELISA
Produktnummer ABIN5510757
  • Target Alle TFF1 ELISA Kits anzeigen
    TFF1 (Trefoil Factor 1 (TFF1))
    Bindungsspezifität
    AA 22-87
    Reaktivität
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Nachweismethode
    Colorimetric
    Methodentyp
    Sandwich ELISA
    Applikation
    ELISA
    Verwendungszweck
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse TFF1
    Marke
    PicoKine™
    Analytische Methode
    Quantitative
    Spezifität
    Expression system for standard: E.coli, Immunogen sequence: Q22-F87
    Kreuzreaktivität (Details)
    There is no detectable cross-reactivity with other relevant proteins.
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  • Plattentyp
    Pre-coated
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Haltbarkeit
    12 months
  • Target Alle TFF1 ELISA Kits anzeigen
    TFF1 (Trefoil Factor 1 (TFF1))
    Andere Bezeichnung
    Tff1 (TFF1 Produkte)
    Synonyme
    BCEI ELISA Kit, D21S21 ELISA Kit, HP1.A ELISA Kit, HPS2 ELISA Kit, pNR-2 ELISA Kit, pS2 ELISA Kit, Bcei ELISA Kit, PS2 ELISA Kit, bcei ELISA Kit, d21s21 ELISA Kit, hp1.a ELISA Kit, hps2 ELISA Kit, p1 ELISA Kit, p1-a ELISA Kit, pnr-2 ELISA Kit, ps2 ELISA Kit, tff1 ELISA Kit, xP1 ELISA Kit, xp1-L ELISA Kit, xp1 ELISA Kit, TFF1 ELISA Kit, Ps2 ELISA Kit, trefoil factor 1 ELISA Kit, trefoil factor 1 S homeolog ELISA Kit, trefoil factor 1, gene 2 S homeolog ELISA Kit, TFF1 ELISA Kit, Tff1 ELISA Kit, tff1.S ELISA Kit, tff1.2.S ELISA Kit, LOC100358238 ELISA Kit
    Hintergrund

    Protein Function: Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents.

    Background: TFF1(Trefoil factor 1), also known as pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera directed to the TFF1 C terminus. Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

    Synonyms: Trefoil factor 1, Protein pS2, Tff1, Bcei, Ps2,

    Full Gene Name: trefoil factor 1

    Cellular Localisation: Secreted.
    UniProt
    Q08423
    Pathways
    EGFR Signaling Pathway
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