Anti-Oxidized Low Density Lipoprotein Antibody ELISA Kit

Produktnummer ABIN5067631

Produktdetails

Target: Anti-Oxidized Low Density Lipoprotein Antibody

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 37-1200 mU/mL

Untere Nachweisgrenze: 37 mU/mL

Applikation: ELISA

Verwendungszweck: Enzyme Immunoassay For The Quantitative Determination Of Human IgG Autoantibodies Against Oxidised Low Density Lipoprotein In Serum

Proben: Serum

Analytische Methode: Quantitative

Spezifität: Antibodies against oxLDL,Anti oxidized LDL autoantibodies

Bestandteile: plate, assay buffer, wash buffer, standards, cotnrols, conjugate, substrate, stop solution

Benötigtes Material: pipettes, tubes, reader

Anwendungsinformationen

Probenmenge: 20 μL

Plattentyp: Pre-coated

Protokoll: Oxidized low density lipoprotein (oLDL) is believed to play a critical role in the development and progression of atherosclerosis. Accumulation of oLDL in macrophages and smooth muscle cells causes foam cell formation, an initial step in the disease. Autoantibodies against oxidatively modified LDL can be used as a parameter that consistently mirrors the occurrence of oxidation processes taking place in vivo. In fact, elevated levels of autoantibodies against oLDL have been detected in the blood stream of patients with coronary artery disease. Moreover, recent studies indicate a correlation between autoantibodies against oLDL and the progression of carotid atherosclerosis. Increased serum concentrations of oLAB have also been described in various diseases such as pre-eclampsia and systemic lupus erythematosus. Decreased oLAB titers were observed during septicemia and myocardial infarction.

Testpräzision: Intra-assay (n=8) ≤ 4%, Inter-assay (n=5) ≤ 8%

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: ≤ 0.1 % Proclin

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Antigendetails

Target: Anti-Oxidized Low Density Lipoprotein Antibody

Andere Bezeichnung: anti-oxLDL antibody

Substanzklasse: Antibody