FNDC5 ELISA Kit

Produktnummer ABIN2745465

Produktdetails FNDC5 ELISA Kit

Target: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Reaktivität: Human, Maus, Ratte, Affe

Nachweismethode: Colorimetric

Methodentyp: Competition ELISA

Detektionsbereich: 0.001-5 μg/mL

Untere Nachweisgrenze: 0.001 μg/mL

Applikation: ELISA

Proben: Cell Culture Supernatant, Plasma, Serum

Analytische Methode: Quantitative

Spezifität: Detects human irisin. It should also work in mouse, rat and monkey biological samples.

Kreuzreaktivität: Human, Affe, Maus, Ratte (Rattus)

Keine Kreuzreaktivität: Maus

Kreuzreaktivität (Details): Does not cross-react with FNDC4, human adiponectin, human Nampt, human RBP4, human clusterin, human leptin, human vaspin, human GPX3, human resistin, human ACE2, human lipocalin-2, human ANGPTL3, human ANGPTL6, human DNER, human DLK1, human calreticulin, human IL-33, mouse Nampt, mouse clusterin, mouse vaspin or mouse resistin.

Sensitivität: 1 ng/mL

Produktmerkmale: Irisin Competitive ELISA Kit (Twin Plex)

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: +4°C
12 months after the day of manufacturing. See expiry date on ELISA Kit box.

Details zu FNDC5

Target: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Andere Bezeichnung: Irisin (FNDC5 Produkte)

Synonyme: FRCP2 ELISA Kit, irisin ELISA Kit, 1500001L03Rik ELISA Kit, AI836596 ELISA Kit, C87088 ELISA Kit, PeP ELISA Kit, Pxp ELISA Kit, fndc5 ELISA Kit, si:dkey-264p5.1 ELISA Kit, zgc:158684 ELISA Kit, fibronectin type III domain containing 5 ELISA Kit, fibronectin type III domain containing 5b ELISA Kit, FNDC5 ELISA Kit, Fndc5 ELISA Kit, fndc5b ELISA Kit

Hintergrund: Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. Circulating irisin levels were shown to be upregulated after acute exercise. Increase of irisin under conditions of obesity may indicate a physiological function to improve glucose tolerance.

UniProt: Q8NAU1

Pathways: Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation