ICA ELISA Kit

Produktnummer ABIN2648680

Produktdetails ICA ELISA Kit

Target: ICA (Islet Cell Antibody (ICA))

Reaktivität: Human

Nachweismethode: Colorimetric

Applikation: ELISA

Proben: Serum

Sensitivität: n/a

Produktmerkmale: Type 1 diabetes, also known as insulin-dependent diabetes mellitus (IDDM), results from a chronic autoimmune process which destructs the insulin-secreting pancreatic beta cells. This is caused by simultaneous action of specific auto-reactive CD4+ and CD8+ T lymphocytes. Even before the onset of type 1 diabetes autoantibodies against different antigens of the islet cells can be detected in the serum of those patients. This process may take years to complete and may occur at any time at all ages.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Probenmenge: 50 μL

Plattentyp: Pre-coated

Protokoll: The ICA Screen ELISA Assay Kit system uses the ability of IC autoantibodies to act di-valently, that is, to form a bridge between autoantigens (highly purified material from primate source) coated onto the plate and liquid phase autoantigen-Biotin. In the first step IC autoantibodies from the sample bind to autoantigens coated on the microtiter plate. In a second step IC-autoantigen-Biotin binds to this complex which correlates with the amount of IC autoantibodies in patient's serum. Unbound IC-autoantigen-Biotin is removed by washing.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Details zu ICA

Target: ICA (Islet Cell Antibody (ICA))

Andere Bezeichnung: ICA (Islet Cell Antibody) (ICA Produkte)

Synonyme: PICA ELISA Kit, Ica ELISA Kit, mICA ELISA Kit, transferrin ELISA Kit, RIKEN cDNA 1300017J02 gene ELISA Kit, TF ELISA Kit, 1300017J02Rik ELISA Kit

Substanzklasse: Antibody

Pathways: Transition Metal Ion Homeostasis