Cathepsin E Inhibitor Screening Kit (Fluorometric)

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Antigen
  • CTSE
  • ce1
  • ce2
  • cate
  • CATE
  • A430072O03Rik
  • C920004C08Rik
  • CE
  • CatE
  • CEA
  • CEB
  • Ctsea
  • cathepsin E
  • hypothetical protein
  • CTSE
  • TP03_0056
  • Smp_184930
  • ctse
  • PGTG_08035
  • Ctse
Applikation
Binding Studies (Bind), Detection (D), Screening Assay (ScA)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Nachweismethode Fluorometric
Produktmerkmale Cathepsin E Inhibitor Screening Kit utilizes the ability of Cathepsin E to cleave a synthetic MCA-based peptide substrate to release free MCA, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin E-specific inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the MCA fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize the potential inhibitors of Cathepsin E.
Screen/study/characterize potential inhibitors of Cathepsin E
Bestandteile CTSE Assay Buffer
Human Cathepsin E
CTSE Substrate
CTSE Inhibitor (1 mM Pepstatin A in DMSO)
Andere Bezeichnung Cathepsin E (CTSE ELISA Kit Abstract)
Hintergrund Cathepsin E (CTSE, EC: 3.4.23.34) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that is found in highest concentration on the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of the gastric cancers.
Forschungsgebiet Immunology, Adaptive Immunity, Innate Immunity, Proteases
Applikationshinweise Screen/study/characterize potential inhibitors of Cathepsin E
Beschränkungen Nur für Forschungszwecke einsetzbar
Lagerung -20 °C
Haltbarkeit 12 months
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