anti-Kaninchen STAT6 Antikörper für Immunohistochemistry

Recommended STAT6 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Antikörper
  • D12S1644
  • IL-4-STAT
  • STAT6B
  • STAT6C
  • signal transducer and activator of transcription 6
  • signal transducer and activator of transcription 6-like
  • STAT6
  • Stat6
  • LOC100859543
Epitop
C-Term
87
42
17
15
15
11
11
9
8
6
5
5
5
5
5
4
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
418
187
131
22
18
16
14
14
8
5
3
2
1
1
1
Wirt
Kaninchen
289
155
6
1
1
Klonalität
Polyklonal
Konjugat
Dieser STAT6 Antikörper ist unkonjugiert
16
15
15
13
12
11
9
7
7
5
5
5
5
5
5
5
5
5
5
4
3
3
3
3
3
3
3
2
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
335
160
148
68
49
48
39
36
35
10
8
4
3
2
2
1
1
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2780481
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
8.666256 ABIN2777200 IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 1
8.666256 ABIN574485 IHC IHC (p) WB Rabbit IgG AA 614-663 Anmelden zum Anzeigen Polyclonal 0
8.666256 ABIN2707113 IHC WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
8.666256 ABIN2707114 IP IHC WB Rabbit pTyr641 Anmelden zum Anzeigen Polyclonal 0
8.666256 ABIN2992673 IHC WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN602358 IHC Rabbit IgG pThr645 Anmelden zum Anzeigen Polyclonal 0
1 ABIN602357 IHC WB Rabbit IgG pTyr641 Anmelden zum Anzeigen Polyclonal 0
1 ABIN602355 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN602356 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN2628869 IHC IHC (p) WB Rabbit Internal Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN2628870 IHC IHC (p) IP WB Rabbit pTyr641 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1938718 IF IHC IHC (p) Rabbit IgG AA 600-650 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1938717 IF IHC IHC (p) IP WB Rabbit IgG AA 600-650 Anmelden zum Anzeigen Polyclonal 0
1 ABIN3071415 IP IHC WB Rabbit IgG Center, pTyr641 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Antikörper
Epitop C-Term
(87), (42), (17), (15), (15), (11), (11), (9), (8), (6), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
(418), (187), (131), (22), (18), (16), (14), (14), (8), (5), (3), (2), (1), (1), (1)
Wirt Kaninchen
(289), (155), (6), (1), (1)
Klonalität
Polyklonal
Konjugat Dieser STAT6 Antikörper ist unkonjugiert
(16), (15), (15), (13), (12), (11), (9), (7), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(335), (160), (148), (68), (49), (48), (39), (36), (35), (10), (8), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-STAT6 Antikörper

Target Details STAT6 Anwendungsinformationen Handhabung Referenzen für anti-STAT6 Antikörper (ABIN2780481) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN984538.
Sequenz TEQDLTKLLL EGQGESGGGS LGAQPLLQPS HYGQSGISMS HMDLRANPSW
Homologie Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against STAT6. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human STAT6
Plasmids, Primers & others

Target Details STAT6

Produktdetails anti-STAT6 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-STAT6 Antikörper (ABIN2780481) Bilder zurück nach oben
Antigen
Andere Bezeichnung STAT6 (STAT6 Antibody Abstract)
Hintergrund STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.
Alias Symbols: D12S1644, IL-4-STAT, STAT6B, STAT6C
Protein Interaction Partner: UBC, IRF4, PDE12, EHD1, USP8, API5, PGGT1B, EP300, TRIM28, JAK3, RCN3, LITAF, IL4R, EEF1A1, VKORC1, PTPN2, STAT2, JAK1, IFNG, IFNAR1, SRXN1, PSAT1, DSTN, SEC24A, AHCYL1, SSSCA1, NUBP2, SH3BGRL, RAD23B, PPM1G, IGBP1, CEBPE, SND1, SUMO2, FCER2, SFPQ, IGHE,
Protein Size: 847
Molekulargewicht 94 kDa
Gen-ID 6778
NCBI Accession NM_003153, NP_003144
UniProt P42226
Pathways JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response

Anwendungsinformationen

Produktdetails anti-STAT6 Antikörper Target Details STAT6 Handhabung Referenzen für anti-STAT6 Antikörper (ABIN2780481) Bilder zurück nach oben
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 847 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-STAT6 Antikörper Target Details STAT6 Anwendungsinformationen Referenzen für anti-STAT6 Antikörper (ABIN2780481) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-STAT6 Antikörper (ABIN2780481)

Produktdetails anti-STAT6 Antikörper Target Details STAT6 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Blanchard, Durual, Estienne, Emami, Vasseur, Cuber: "Eotaxin-3/CCL26 gene expression in intestinal epithelial cells is up-regulated by interleukin-4 and interleukin-13 via the signal transducer and activator of transcription 6." in: The international journal of biochemistry & cell biology, Vol. 37, Issue 12, pp. 2559-73, 2005

Bilder

Produktdetails anti-STAT6 Antikörper Target Details STAT6 Anwendungsinformationen Handhabung Referenzen für anti-STAT6 Antikörper (ABIN2780481) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (C-Term) antibody (ABIN2780481) WB Suggested Anti-STAT6 Antibody Titration: 0.2-1 ug/ml Positive Control: recombin...
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (C-Term) antibody (ABIN2780481) anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (C-Term) antibody (Image 2)