anti-Human STAT2 Antikörper für Enzyme Immunoassay

Recommended STAT2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) Antikörper
  • wu:fj84d07
  • p113
  • stat2
  • 1600010G07Rik
  • AW496480
  • ISGF-3
  • P113
  • STAT113
  • signal transducer and activator of transcription 2
  • AGAP000099-PA
  • stat2
  • STAT2
  • Stat2
Epitop
C-Term
46
34
18
17
15
15
13
11
11
9
8
7
7
7
6
5
5
4
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
258
99
82
10
3
3
2
2
2
2
1
Wirt
Kaninchen
279
19
1
Klonalität
Polyklonal
Konjugat
Dieser STAT2 Antikörper ist unkonjugiert
12
10
9
6
6
6
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
244
117
109
45
27
23
17
13
9
6
3
3
2
2
1
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN357081
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN5551836 EIA WB Rabbit IgG N-Term, pTyr690 Anmelden zum Anzeigen Polyclonal 0
1 ABIN641239 CA DB EIA IA ISt ELISA WB Rabbit Anmelden zum Anzeigen Polyclonal 0

General

Antigen Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) Antikörper
Epitop C-Term
(46), (34), (18), (17), (15), (15), (13), (11), (11), (9), (8), (7), (7), (7), (6), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(258), (99), (82), (10), (3), (3), (2), (2), (2), (2), (1)
Wirt Kaninchen
(279), (19), (1)
Klonalität
Polyklonal
Konjugat Dieser STAT2 Antikörper ist unkonjugiert
(12), (10), (9), (6), (6), (6), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(244), (117), (109), (45), (27), (23), (17), (13), (9), (6), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-STAT2 Antikörper

Target Details STAT2 Anwendungsinformationen Handhabung Referenzen für anti-STAT2 Antikörper (ABIN357081) Bilder
Spezifität This antibody detects STAT2 at C-term.
Reinigung Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human STAT2.
Isotyp Ig Fraction
Plasmids, Primers & others

Target Details STAT2

Produktdetails anti-STAT2 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-STAT2 Antikörper (ABIN357081) Bilder zurück nach oben
Antigen
Andere Bezeichnung STAT2 (STAT2 Antibody Abstract)
Hintergrund STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.Synonyms: Signal transducer and activator of transcription 2, p113
Molekulargewicht 97916 Da
Gen-ID 6773, 9606
UniProt P52630
Pathways JAK-STAT Signalweg, Hepatitis C, CXCR4-mediated Signaling Events

Anwendungsinformationen

Produktdetails anti-STAT2 Antikörper Target Details STAT2 Handhabung Referenzen für anti-STAT2 Antikörper (ABIN357081) Bilder zurück nach oben
Applikations-hinweise ELISA 1 : 1,000. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-STAT2 Antikörper Target Details STAT2 Anwendungsinformationen Referenzen für anti-STAT2 Antikörper (ABIN357081) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-STAT2 Antikörper (ABIN357081)

Produktdetails anti-STAT2 Antikörper Target Details STAT2 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Rodriguez, Wang, Horvath: "Hendra virus V protein inhibits interferon signaling by preventing STAT1 and STAT2 nuclear accumulation." in: Journal of virology, Vol. 77, Issue 21, pp. 11842-5, 2003

Gotoh, Takeuchi, Komatsu, Yokoo: "The STAT2 activation process is a crucial target of Sendai virus C protein for the blockade of alpha interferon signaling." in: Journal of virology, Vol. 77, Issue 6, pp. 3360-70, 2003

Bilder

Produktdetails anti-STAT2 Antikörper Target Details STAT2 Anwendungsinformationen Handhabung Referenzen für anti-STAT2 Antikörper (ABIN357081) zurück nach oben
Bilder des Herstellers
 image for anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (C-Term) antibody (ABIN357081) anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (C-Term) antibody
 image for anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (C-Term) antibody (ABIN357081) anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (C-Term) antibody (Image 2)