anti-Pferd PIAS3 Antikörper für Western Blotting

Recommended PIAS3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Protein Inhibitor of Activated STAT, 3 (PIAS3) Antikörper
  • PIAS3
  • Pias3l
  • ZMIZ5
  • protein inhibitor of activated STAT 3
  • protein inhibitor of activated STAT, 3
  • protein inhibitor of activated STAT 3 L homeolog
  • PIAS3
  • pias3
  • Pias3
  • pias3.L
Epitop
Middle Region
16
11
3
2
2
2
2
2
2
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Kaninchen, Ratte (Rattus)
65
31
29
7
6
5
3
2
1
1
Wirt
Kaninchen
62
3
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
58
34
32
15
6
2
2
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2777575
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2592905 ABIN2777574 IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 1
1 ABIN202823 IHC (p) WB Rabbit IgG AA 548-597 Anmelden zum Anzeigen Polyclonal 0
1 ABIN467799 WB Rabbit AA 395-444 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Protein Inhibitor of Activated STAT, 3 (PIAS3) Antikörper
Epitop Middle Region
(16), (11), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Kaninchen, Ratte (Rattus)
(65), (31), (29), (7), (6), (5), (3), (2), (1), (1)
Wirt Kaninchen
(62), (3)
Klonalität
Polyklonal
Applikation Western Blotting (WB)
(58), (34), (32), (15), (6), (2), (2), (2), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-PIAS3 Antikörper

Target Details PIAS3 Anwendungsinformationen Handhabung Referenzen für anti-PIAS3 Antikörper (ABIN2777575) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN981734.
Sequenz DEIQFMEDGS WCPMKPKKEA SEVCPPPGYG LDGLQYSPVQ GGDPSENKKK
Homologie Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Rabbit: 79%, Rat: 79%
Produktmerkmale This is a rabbit polyclonal antibody against PIAS3. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human PIAS3

Target Details PIAS3

Produktdetails anti-PIAS3 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-PIAS3 Antikörper (ABIN2777575) Bilder zurück nach oben
Antigen
Andere Bezeichnung PIAS3 (PIAS3 Antibody Abstract)
Hintergrund PIAS3 is a member of the protein inhibitor of activated STAT (PIAS) family. It also activates TGF-beta/SMAD transcriptional responses. This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ14651, ZMIZ5
Protein Interaction Partner: UBC, HIC1, TRIM63, TRIM55, TAB2, SUMO1, CBS, SUMO2, SUMO3, STAT3, NCOA2, CREM, PRPF40A, SERPINA10, GEMIN4, UBE2I, SKIL, HNRNPK, ZFHX3, SERBP1, SATB1, ERBB4, Bcl11a, ELAVL1, PPP1CA, Grm7, Grm8, Grm6, Grm4, TRIM8, RAC1, C19orf60, CARHSP1, UBA1, PSMC1, TRIM2
Protein Size: 628
Molekulargewicht 68 kDa
Gen-ID 10401
NCBI Accession NM_006099, NP_006090
UniProt Q9Y6X2
Pathways JAK-STAT Signalweg

Anwendungsinformationen

Produktdetails anti-PIAS3 Antikörper Target Details PIAS3 Handhabung Referenzen für anti-PIAS3 Antikörper (ABIN2777575) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 628 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-PIAS3 Antikörper Target Details PIAS3 Anwendungsinformationen Referenzen für anti-PIAS3 Antikörper (ABIN2777575) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PIAS3 Antikörper (ABIN2777575)

Produktdetails anti-PIAS3 Antikörper Target Details PIAS3 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Roukens, Alloul-Ramdhani, Vertegaal, Anvarian, Balog, Deelder, Hensbergen, Baker: "Identification of a new site of sumoylation on Tel (ETV6) uncovers a PIAS-dependent mode of regulating Tel function." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2342-57, 2008

Bilder

Produktdetails anti-PIAS3 Antikörper Target Details PIAS3 Anwendungsinformationen Handhabung Referenzen für anti-PIAS3 Antikörper (ABIN2777575) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (Middle Region) antibody (ABIN2777575) anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (Middle Region) antibody