Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Human IL21 Protein expressed in Escherichia coli (E. coli) - ABIN413500
Yoon, Zhang, Berner, Blom, Choi: Notch ligands expressed by follicular dendritic cells protect germinal center B cells from apoptosis. in Journal of immunology (Baltimore, Md. : 1950) 2009
Show all 2 Pubmed References
this study shows that Th9 cells promote antitumor immunity via IL-21 (zeige IL17C Proteine)
AD patients, especially those with acute lesions, exhibited elevated serum IL-21 (zeige IL17C Proteine) levels. Therefore, IL-21 (zeige IL17C Proteine) might be associated with the acute aggravation of AD.
Study shows that IL-21 (zeige IL17C Proteine) levels were non-specifically elevated across all febrile children, irrespective of Kawasaki disease diagnosis.
These results suggest that cetuximab treatment in combination with IL-21 adjuvant therapy in patients with EGFR-positive pancreatic cancer results in significant NK cell activation, irrespective of KRAS mutation status, and may be a potential therapeutic strategy
serum IL-21 levels at 12 weeks treatment was significantly elevated, which can predict the EVR, and contributes to individualization of antiviral therapy in HBeAg-positive CHB+NAFLD patients.
IL-23 (zeige IL23A Proteine) activates gammadelta T cells in early stage PNS, which amplifies the Th17 cell population and leads to kidney injury through the secretion of IL-21 (zeige IL17C Proteine).
IL-21 (zeige IL17C Proteine) promotes the survival and CTLA-4 (zeige CTLA4 Proteine) expression of Tregs and enhanced the suppressive capacity of Tregs during HIV infection. These results broaden the understanding of HIV pathogenesis and provide critical information for HIV interventions.
IL-21 (zeige IL17C Proteine) are important in the pathophysiology of chronic rhinosinusitis with nasal polyposis
Data show that interleukin-21-primed cytotoxic T-cell lymphocytes (CTL) with cytotoxic T-lymphocyte associated protein 4 (CTLA-4 (zeige CTLA4 Proteine)) blockade is safe and produces durable clinical responses.
These results indicate that significant increased IL-21 (zeige IL17C Proteine) expression present within the adenoma/CRC (zeige CALR Proteine) microenvironment might have a potential predicating significance for survival time in patients with CRC (zeige CALR Proteine).
this study shows that IL4 (zeige IL4 Proteine) and IL21 cooperate to induce the high Bcl6 (zeige BCL6 Proteine) protein level required for germinal center formation
This finding warrants future development of IL-21 and IL-7 (zeige IL7 Proteine) co-expressing whole-cell cancer vaccines and their relevant combinatorial regimens.
The studies link IL-21 to T cell ontogeny, self-reactivity, and humoral autoimmunity.
IL-21 signaling has a critical role in optimal host resistance against Mycobacterium tuberculosis infection
memory-like NK cells expansion depends on IL-21, and is involved in vaccine-induced protective immunity against a bacterial pathogen
IL-6 (zeige IL6 Proteine) is identified as a master regulator of IL-21 in effector CD8 (zeige CD8A Proteine)(+) T cells.
Our work suggests that IL-21 regulates megakaryocyte development and platelet homeostasis. Thus, IL-21 may link immune responses to physiological or pathological platelet-dependent processes.
we identify novel distal regulatory elements in the mouse Il21 locus and demonstrate a dynamic long-range chromatin interaction between the Il21 promoter and these regulatory elements, which contributes to the regulated expression of IL-21
this study shows that IL-21 acts as a potent inhibitor of a IL-17A (zeige IL17A Proteine)-producing T-cell subset during Mycobacterium bovis Bacillus infection
IL-21 may play an important role in the pathogenesis of SSc (zeige CYP11A1 Proteine) as a Th17 effector cytokine, and IL-21 may induce the differentiation of Th17 cells in the BLM (zeige BLM Proteine)-induced systemic sclerosis mouse model via Il21R (zeige IL21R Proteine).
The results revealed that the peak expression of IL6 (zeige IL6 Proteine) and 21 was on DPV 28 which correlated well with the FMDV antibody titer and plummeted to the prevaccination titer level by 60 DPV.
This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
, interleukin-21 isoform