Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Mouse (Murine) IL12A Antikörper:
anti-Rat (Rattus) IL12A Antikörper:
anti-Human IL12A Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Monoclonal IL12A Primary Antibody für CyTOF, FACS - ABIN4899729
Liu, Bi, Xue, Zhang, Yang, Chen, Lu, Zhang, Liu, Wang, Wang, Chu, Yang: Dendritic cell SIRT1-HIF1α axis programs the differentiation of CD4+ T cells through IL-12 and TGF-β1. in Proceedings of the National Academy of Sciences of the United States of America 2015
Show all 10 Pubmed References
Human Monoclonal IL12A Primary Antibody für FACS - ABIN4896565
Gironi, Saresella, Rovaris, Vaghi, Nemni, Clerici, Grossi: A novel data mining system points out hidden relationships between immunological markers in multiple sclerosis. in Immunity & ageing : I & A 2013
Show all 5 Pubmed References
Human Monoclonal IL12A Primary Antibody für FACS - ABIN4896566
Richter, Thieme, Bandoła, Laugsch, Anastassiadis, Brenner: Generation of inducible immortalized dendritic cells with proper immune function in vitro and in vivo. in PLoS ONE 2013
Show all 3 Pubmed References
Human Monoclonal IL12A Primary Antibody für FACS - ABIN4896563
van Herwijnen, Wieten, van der Zee, van Kooten, Wagenaar-Hilbers, Hoek, den Braber, Anderton, Singh, Meiring, van Els, van Eden, Broere: Regulatory T cells that recognize a ubiquitous stress-inducible self-antigen are long-lived suppressors of autoimmune arthritis. in Proceedings of the National Academy of Sciences of the United States of America 2012
Show all 2 Pubmed References
IL-12 receptor signalling in keratinocytes initiates a protective transcriptional programme that limits skin inflammation.
The authors found that the expressions of the mRNAs of both IL-12p35 and IL-12p40 were significantly reduced in the oxygen-induced retinopathy retinas compared to that of the room air-raised control. The results suggest that IL-12 plays important roles in inhibiting pathological retinal neovascularization.
IL-12p35 suppresses lymphocyte proliferation, induces expansion of IL-10 (zeige IL10 Antikörper)-expressing and IL-35-expressing B cells and ameliorates autoimmune uveitis.
IL-35-transduced adipocyte-derived mesenchymal stem cells in vivo can enhance proliferation of CD4 (zeige CD4 Antikörper)(+) CD25 (zeige IL2RA Antikörper)(+) Treg cells and suppress the function of effector T cells such as T helper (Th) 1 (zeige TH1L Antikörper), Th2 and Th17 cells and may reduce the development of allograft rejection.
findings show that IL-12 and other proinflammatory cytokines transduce signals through the TCR signalosome in a manner that requires Fyn activity and self-peptide-MHC (self-pMHC) interactions.
this study shows that a systemic IL-12 primes intestinal cells that became more prone to develop inflammatory responses, which is long-lasting because intestinal cells maintain their inflammatory potential and their ability to aggravate colitis
These results suggest a correlation between CRMP2 (zeige DPYSL2 Antikörper) phosphorylation and AD pathophysiology, and indicate the effectiveness of pioglitazone treatment at the pre-Abeta (zeige APP Antikörper) accumulation stage in AD model mice.
Data show that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) expressing plasmid downregulates the expression of pro-inflammatory cytokines and upregulates the expression of anti-inflammatory cytokines.
Data suggest that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) contributes to the increased susceptibility to secondary pneumococcal pneumonia.
Deficiency of IL-12p35 limited AMI (zeige CFD Antikörper)-induced cardiac injury by promoting pro-angiogenesis and anti-inflammatory functions of monocytes
The present study investigated the relationship of IL35 (zeige EBI3 Antikörper) in patients with immunorelated hemocytopenia (IRH (zeige CXCL12 Antikörper)). Serum level of IL35 (zeige EBI3 Antikörper) was decreased in untreated patients with IRH (zeige CXCL12 Antikörper) compared with remission patients (P<0.01) and was significantly associated with clinical indexes.
The overall results showed that cancer risk was increased by IL-12A rs568408 (GG versus GA + AA: P = 0.004; G versus A: P = 0.005) and IL-12B (zeige IL12B Antikörper) rs3212227 (AA versus AC + CC: P = 0.004; CC versus AA + AC: P = 0.03; A versus C: P = 0.007) polymorphisms. However, we failed to detect any significant associations between the IL-12A rs2243115 polymorphism and cancer risk in either the overall or the subgroup analyses.
IL-35 is a relatively newly discovered member of the IL-12 family which are unique in structure as they are dimer formed by two subunits; recent findings have shown abnormal expression of IL-35 in inflammatory autoimmune diseases and functional analysis suggested that IL-35 is critical in the onset and development of these diseases. [Review]
In the study, 250 ONFH patients and 228 matched healthy controls from Shandong Province were recruited to evaluate the influence of interleukin-10 (IL-10 (zeige IL10 Antikörper)) rs1800872, IL-12 rs3212227 and tumor necrosis factor-(TNF-alpha (zeige TNF Antikörper)) rs1800629 polymorphism in osteonecrosis of the femoral head (ONFH). IL-12 rs3212227 AC genotype confer genetically susceptibility to ONFH in the Chinese Han population.
The results suggest IL12A genotype predict higher risk of death and progression, respectively, in NSCLC patients.
Pancreatic ductal carcinoma cells produce IL35 (zeige EBI3 Antikörper) to recruit monocytes via CCL5 (zeige CCL5 Antikörper) and induce macrophage to promote angiogenesis via expression of CXCL1 (zeige CXCL1 Antikörper) and CXCL8 (zeige IL8 Antikörper).
Polymorphisms of IFNL3 rs8099917 and IL12A rs568408 contribute to survival of HD patients, but not as independent factors.
The anti-EGFR (zeige EGFR Antikörper) viroplexes with IL-12 and salmosin genes exhibited the most effective therapeutic efficacy in a mouse tumor model, especially when combined with doxorubicin.
The findings suggest that not the IFN-gamma (zeige IFNG Antikörper) (+874) A/T but the IL-12 (-1188) A/C polymorphism is correlated with subacute sclerosing panencephalitis (SSPE), and having an AA genotype or A allele decreases the risk of developing SSPE by 2.06- and 1.65-fold, respectively.
The results showed that the expression of TNF-alpha (zeige TNF Antikörper), iNOS (zeige NOS2 Antikörper), and IL-6 (zeige IL6 Antikörper) in alveolar macrophages was up-regulated by stimulation with the recombinant Mce4A protein of M. bovis; in contrast, expression of IL-12 was unaffected.[IL-6 (zeige IL6 Antikörper), IL-12]
This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
, IL-12 subunit p35
, cytotoxic lymphocyte maturation factor 35 kDa subunit
, interleukin 12a p35 subunit
, interleukin-12 subunit alpha
, interleukin 12 p35 subunit
, IL-12, subunit p35
, IL35 subunit
, NF cell stimulatory factor chain 1
, NK cell stimulatory factor chain 1
, cytotoxic lymphocyte maturation factor 1, p35
, interleukin 12, p35
, interleukin-12 alpha chain
, natural killer cell stimulatory factor 1, 35 kD subunit
, interleukin 12 35kDa subunit
, interleukin 12 polypeptide 35
, natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35
, interleukin 12B
, interleukin-12 p35 subunit
, IL-12 p35
, interleukin 12
, Cytotoxic lymphocyte maturation factor 35 kDa subunit
, interleukin 12 35kD subunit
, IL-12p35 subunit