anti-Hund HTR7 Antikörper für Immunocytochemistry

Recommended HTR7 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7) Antikörper
  • 5-HT7
  • 5-HT-dro
  • 5-HT-dro1
  • 5-HT7Dro
  • 5-HT[7]Dro
  • 5-HT[[7Dro]]
  • 5-HT[[7]]
  • 5-HT[[7]]Dro
  • 5-HT[[dro1]]
  • 5-HTdro1
  • 5HT-7
  • 5HT-R1
  • 5HT-dro
  • 5HT-dro1
  • 5HT[[7Dro]]
  • 5htdror
  • CG12073
  • DRO1
  • Dm5HTdro1
  • Dmel\\CG12073
  • 5Ht7
  • 5HT7
  • htr7-A
  • 5-hydroxytryptamine receptor 7
  • 5-hydroxytryptamine (serotonin) receptor 7
  • 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled L homeolog
  • HTR7
  • 5-HT7
  • LOC752003
  • Htr7
  • htr7.L
Reaktivität
Hund, Human, Maus, Ratte (Rattus)
117
20
18
17
9
9
7
3
3
3
3
2
2
2
2
1
1
1
Wirt
Kaninchen
103
16
Klonalität
Polyklonal
Konjugat
Dieser HTR7 Antikörper ist unkonjugiert
4
4
4
3
3
3
Applikation
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
52
51
44
27
11
3
2
2
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN188708
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN4276903 ICC IF WB Rabbit Anmelden zum Anzeigen Polyclonal 0

General

Antigen 5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7) Antikörper
Reaktivität Hund, Human, Maus, Ratte (Rattus)
(117), (20), (18), (17), (9), (9), (7), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Wirt Kaninchen
(103), (16)
Klonalität
Polyklonal
Konjugat Dieser HTR7 Antikörper ist unkonjugiert
(4), (4), (4), (3), (3), (3)
Applikation Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(52), (51), (44), (27), (11), (3), (2), (2), (1)
Pubmed 11 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-HTR7 Antikörper

Target Details HTR7 Anwendungsinformationen Handhabung Referenzen für anti-HTR7 Antikörper (ABIN188708) Bilder
Spezifität This sequence is identical for 5-HT7R splice variants in the rat (5-HT7Ra/b/c), human (5-HT7Ra/b/d) and human 5-HT7, the mouse 5-HT7R. It is 93 % conserved with dog 5-HT7Ra/b, and 81 % conserved with pig 5-HT7R. The 5HT7 antibody recognizes all described 5HT7 receptor splice variants.
Reinigung Protein G purified
Immunogen This antibody was developed by immunizing rabbits with a mixture of synthetic peptides corresponding to amino acids 13-28 of the rat 5-HT7R (AAA42134.1).
Plasmids, Primers & others

Target Details HTR7

Produktdetails anti-HTR7 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-HTR7 Antikörper (ABIN188708) Bilder zurück nach oben
Antigen
Andere Bezeichnung 5-HT7 (HTR7 Antibody Abstract)
Hintergrund Gene Symbol: HTR7
Molekulargewicht Theoretical MW: 54 kDa
Gen-ID 3363
UniProt P32305
Pathways JAK-STAT Signalweg

Anwendungsinformationen

Produktdetails anti-HTR7 Antikörper Target Details HTR7 Handhabung Referenzen für anti-HTR7 Antikörper (ABIN188708) Bilder zurück nach oben
Applikations-hinweise Western Blot 1-2 μg/mL, Immunocytochemistry/Immunofluorescence 1:10-1:2000In human brain, a 50 kDa band is observed. Both 45 kDa and 50 kDa bands have been observed in various human glioblastoma cell lines and in the human microglial MC-3 cell lines. Bands in the 45-50 kDa range correspond to the predicted molecular weight for the 5HT7 receptor. The 5HT7 receptor also has putative sites for N-linked glycosylation and phosphorylation which may lead to variations in observed molecular weights. Use in Immunocytochemistry/Immunoflourescence was reported in the literature (PMID: 17940054) The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-HTR7 Antikörper Target Details HTR7 Anwendungsinformationen Referenzen für anti-HTR7 Antikörper (ABIN188708) Bilder zurück nach oben
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.05 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze-thaw cycles
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Referenzen für anti-HTR7 Antikörper (ABIN188708)

Produktdetails anti-HTR7 Antikörper Target Details HTR7 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Gautam, Banskota, Regmi, Ahn, Jeon, Jeong, Kim, Nam, Jeong, Kim: "Tryptophan hydroxylase 1 and 5-HT7 receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signaling." in: Molecular cancer, Vol. 15, Issue 1, pp. 75, 2016 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)).

Speranza, Giuliano, Volpicelli, De Stefano, Lombardi, Chambery, Lacivita, Leopoldo, Bellenchi, di Porzio, Crispino, Perrone-Capano: "Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics." in: Frontiers in behavioral neuroscience, Vol. 9, pp. 62, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Immunocytochemistry,Western Blotting,Immunofluorescence

Cho, Ki, Kim, Oh, Yang, Kim, Lee, Yoon, Choi: "Expression of the spinal 5-HT7 receptor and p-ERK pathway in the carrageenan inflammatory pain of rats." in: Korean journal of anesthesiology, Vol. 68, Issue 2, pp. 170-4, 2015 (Probematerial (Species): Rat (Rattus)). Weitere Details: Western Blotting

Holst, Guseva, Schindler, Sixt, Braun, Chopra, Pabst, Ponimaskin: "The serotonin receptor 5-HT₇R regulates the morphology and migratory properties of dendritic cells." in: Journal of cell science, Vol. 128, Issue 15, pp. 2866-80, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Immunocytochemistry,Immunofluorescence

García-Iglesias, Mendoza-Garrido, Gutiérrez-Ospina, Rangel-Barajas, Noyola-Díaz, Terrón: "Sensitization of restraint-induced corticosterone secretion after chronic restraint in rats: involvement of 5-HT? receptors." in: Neuropharmacology, Vol. 71, pp. 216-27, 2013 (Probematerial (Species): Rat (Rattus)). Weitere Details: Western Blotting

Amaya-Castellanos, Pineda-Farias, Castañeda-Corral, Vidal-Cantú, Murbartián, Rocha-González, Granados-Soto: "Blockade of 5-HT7 receptors reduces tactile allodynia in the rat." in: Pharmacology, biochemistry, and behavior, Vol. 99, Issue 4, pp. 591-7, 2011

Pai, Horseman: "Biphasic regulation of mammary epithelial resistance by serotonin through activation of multiple pathways." in: The Journal of biological chemistry, Vol. 283, Issue 45, pp. 30901-10, 2008 (Probematerial (Species): Human). Weitere Details: Western Blotting

Stull, Pai, Vomachka, Marshall, Jacob, Horseman: "Mammary gland homeostasis employs serotonergic regulation of epithelial tight junctions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 42, pp. 16708-13, 2007 Weitere Details: Immunocytochemistry,Western Blotting,Immunofluorescence

León-Ponte, Ahern, OConnell: "Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor." in: Blood, Vol. 109, Issue 8, pp. 3139-46, 2007 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Mahé, Loetscher, Dev, Bobirnac, Otten, Schoeffter: "Serotonin 5-HT7 receptors coupled to induction of interleukin-6 in human microglial MC-3 cells." in: Neuropharmacology, Vol. 49, Issue 1, pp. 40-7, 2005 (Probematerial (Species): Human). Weitere Details: Western Blotting

Mahé, Bernhard, Bobirnac, Keser, Loetscher, Feuerbach, Dev, Schoeffter: "Functional expression of the serotonin 5-HT7 receptor in human glioblastoma cell lines." in: British journal of pharmacology, Vol. 143, Issue 3, pp. 404-10, 2004 (Probematerial (Species): Human). Weitere Details: Western Blotting

Bilder

Produktdetails anti-HTR7 Antikörper Target Details HTR7 Anwendungsinformationen Handhabung Referenzen für anti-HTR7 Antikörper (ABIN188708) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7) antibody (ABIN188708) Western Blot: 5-HT7R Antibody [ABIN188708] - Western blot analysis of 5-HT7R in human...
Western Blotting (WB) image for anti-5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7) antibody (ABIN188708) Western Blot: 5-HT7 Antibody [ABIN1887082] - Analysis of 5-HT7R in A) human brain, B)...