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anti-Human CSF2 Antikörper:
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Human Monoclonal CSF2 Primary Antibody für CyTOF, ELISA (Capture) - ABIN4899320
Hirst, Hallsworth, Peng, Lee et al.: Selective induction of eotaxin release by interleukin-13 or interleukin-4 in human airway smooth muscle cells is synergistic with interleukin-1beta and is mediated by the interleukin-4 receptor ... in American journal of respiratory and critical care medicine 2002
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Human Monoclonal CSF2 Primary Antibody für CyTOF, ELISA (Capture) - ABIN4899319
Biancotto, Grivel, Iglehart, Vanpouille, Lisco, Sieg, Debernardo, Garate, Rodriguez, Margolis, Lederman: Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. in Blood 2007
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Human Monoclonal CSF2 Primary Antibody für ELISA, WB - ABIN1724740
He, Shumansky, Connett, Anthonisen, Paré, Sandford: Association of genetic variations in the CSF2 and CSF3 genes with lung function in smoking-induced COPD. in The European respiratory journal 2008
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Rat (Rattus) Monoclonal CSF2 Primary Antibody für CyTOF, FACS - ABIN4898951
Stojić-Vukanić, Nacka-Aleksić, Pilipović, Vujnović, Blagojević, Kosec, Dimitrijević, Leposavić: Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4+ T cells in aged rats. in Immunity & ageing : I & A 2015
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Human Monoclonal CSF2 Primary Antibody für FACS - ABIN4895921
Alisa, Boswell, Pathan, Ayaru, Williams, Behboudi: Human CD4(+) T cells recognize an epitope within alpha-fetoprotein sequence and develop into TGF-beta-producing CD4(+) T cells. in Journal of immunology (Baltimore, Md. : 1950) 2008
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Human Polyclonal CSF2 Primary Antibody für FACS, IF - ABIN654647
Stone, Vanderman, Willey, Long, Register, Shively, Stehle, Loeser, Ferguson: Osteoarthritic changes in vervet monkey knees correlate with meniscus degradation and increased matrix metalloproteinase and cytokine secretion. in Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2015
Upregulation of GM-CSF and M-CSF (zeige CSF1 Antikörper) production by endothelial cells, an effect that appears to be mediated by NF-kappaB (zeige NFKB1 Antikörper) and to be independent of IL-1 (zeige IL1A Antikörper), may be an additional mechanism through which IL-33 (zeige IL33 Antikörper) contributes to inflammatory activation of the vessel wall.
Oral and periodontal innate immunity is affected by HIV viremia and ART. GCF (zeige GUCY2F Antikörper) IL-8 (zeige IL8 Antikörper), G-CSF (zeige CSF3 Antikörper), as well as serum IL-8 (zeige IL8 Antikörper), MCP-1 (zeige CCL2 Antikörper) and GM-CSF may be useful biomarkers for the detection of disease presence and/or its severity due to HIV infection and ART use.
Data suggest that the intratumoral GM-CSF expression, as a potentially independent prognostic biomarker for recurrence, might improve conventional clinical and pathologic analysis to refine outcome prediction for clinically localized clear-cell renal cell carcinoma (zeige MOK Antikörper) (ccRCC) patients after surgery.
High GM-CSF expression is associated with breast Cancer.
In gastric cancer (GC), tumour-derived GM-CSF activated neutrophils and induced neutrophil PD-L1 (zeige CD274 Antikörper) expression via Janus kinase (JAK (zeige JAK3 Antikörper))-signal transducer and activator of transcription 3 (STAT3 (zeige STAT3 Antikörper)) signalling pathway. The activated PD-L1 (zeige CD274 Antikörper)(+) neutrophils effectively suppressed normal T-cell immunity in vitro and contributed to the growth and progression of human GC in vivo.
The IL-3 (zeige IL-3 Antikörper)/ GM-CSF effected on the myofibroblastic differentiation of human adipose derive stromal cells (hASCs) as well as it did on human dermal fibroblasts (HDFs).
Obesity alters the lung neutrophil infiltration to enhance breast cancer metastasis through IL5 (zeige IL5 Antikörper) and GM-CSF.
Data suggest that the methylotrophic yeast Pichia pastoris is an effective recombinant host for heterologous granulocyte-macrophage colony-stimulating factor (rhGM-CSF) production.
Letter: Knockdown of either filaggrin (zeige FLG Antikörper) or loricrin (zeige LOR Antikörper) increases the productions of interleukin (IL)-1alpha, IL-8 (zeige IL8 Antikörper), IL-18 (zeige IL18 Antikörper) and granulocyte macrophage colony-stimulating factor in stratified human keratinocytes.
Impaired RASGRF1 (zeige RASGRF1 Antikörper)/ERK (zeige EPHB2 Antikörper)-mediated GM-CSF response characterizes CARD9 (zeige CARD9 Antikörper) deficiency in French-Canadians.
TRAF6 (zeige TRAF6 Antikörper) is also required for GM-CSF-induced ubiquitination and activation of Akt (zeige AKT1 Antikörper).
CSF2 stimulates proliferation of trophectoderm cells by activation of the PI3K-and ERK1/2 MAPK (zeige MAPK1 Antikörper)-dependent MTOR (zeige FRAP1 Antikörper) signal transduction cascades.
these data demonstrate that GM-CSF levels during radiotherapy can be used as a prognostic biomarker for lung and esophageal cancer
this study demonstrates that epithelial-derived GM-CSF is a critical early signal during allergic sensitization to cockroach allergen
These impaired macrophage functions in leukemic mice were significantly corrected by IL-3 (zeige IL-3 Antikörper) and GM-CSF treatment indicating the therapeutic benefit of these two cytokines in leukemia.
Both IL-6 (zeige IL6 Antikörper) protein production and transcript levels were downregulated by RA in respiratory tract epithelial cells (LETs) , but upregulated in macrophages (MACs). RA also increased transcript levels of MCP-1 (zeige CPT1B Antikörper), GMCSF, and IL-10 (zeige IL10 Antikörper) in MACs, but not in LETs. Conversely, when LETs, but not MACs, were exposed to RA
T-GM-CSF and -IL-3 (zeige IL-3 Antikörper) significantly, and reciprocally, blunted receptor binding and myeloid progenitor cell proliferation activity of both FL-GM-CSF and -IL-3 (zeige IL-3 Antikörper) in vitro and in vivo
Results indicate GM-CSF as both a key contributor to the pathogenesis of MI and a potential therapeutic target.
GM-CSF is required for the normal balance of leukocyte subsets, including granulocytes, B cells, and naive vs. effector T cells. There was an approximately 3-fold increase in the percentages of granulocytes in Csf2-/- PBMCs. The presence of maximal experimental autoimmune encephalomyelitis in the complete absence of GM-CSF revealed that GM-CSF is not an obligate effector molecule in all forms of EAE.
chemerin (zeige RARRES2 Antikörper) inhibited nuclear factor-kappaB activation and the expression of granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-2 (zeige IL2 Antikörper) (IL-6 (zeige IL6 Antikörper)) by tumor cells and tumor-associated endothelial cell, respectively, via its receptors, and consequently, MDSC induction was impaired, leading to restoration of antitumor T-cell response and decreased tumor angiogenesis.
These findings describe a novel role for GM-CSF as an essential initiating cytokine in cardiac inflammation.
These results demonstrated that bovine colonic cells seem capable to respond to E. bovis merozoite I infection by the upregulation of CXCL10 (zeige CXCL10 Antikörper) and GM-CSF gene transcription.
Data suggest exposure to maternal CSF2 from D5-D7 of development is fundamentally different for female/male blastocysts with respect to embryo elongation, characteristics of transcriptome/methylome, and endometrial interferon tau secretion at D15 (zeige MRPL16 Antikörper).
The increase in calving rate caused by CSF2 treatment involves, in part, more extensive development of extraembryonic membranes and capacity of the conceptus to secrete IFNT2 at day 15 of pregnancy.
immunolocalization studies confirmed the presence of granulocyte-macrophage colony stimulating factor(GM-CSF) in the germ cell line in bovine and human testes and addition of GM-CSF enhances several parameters of sperm motility
the conceptus, through its secretion of IFN-tau, stimulates maternal epithelial expression of COX-2 (zeige PTGS2 Antikörper) and GM-CSF during the peri (zeige PLIN1 Antikörper)-attachment period in the cow.
CSF2 affect embryonic development and enhance embryo competence for posttransfer survival.
Data indicate that differentially expressed IL-17 (zeige IL17A Antikörper), IL-22 (zeige IL22 Antikörper), and IL-23 (zeige IL23A Antikörper) levels are associated with K-ras (zeige HRAS Antikörper) in a stage-specific fashion along colorectal cancer progression and an association was established between mutant K-ras (zeige HRAS Antikörper) and GM-CSF and IFN-gamma (zeige IFNG Antikörper).
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.
, granulocyte-macrophage colony-stimulating factor
, colony stimulating factor 2 (granulocyte-macrophage)
, colony-stimulating factor
, granulocyte-macrophage colony stimulating factor 2
, put. GM-CSF
, granulate-macrophage stimulating factor
, granulocyte-macrophage stimulation factor