Human IgM protein (Fab mu) (HRP) conjugate Source: Human serum Alternative Names: Immunoglobulin M protein (Human) (Fab mu) (HRP) Physical state: Clear, colorless liquid
Aufreinigung
Human IgM protein (Fab mu) (HRP) was purified by delipidation, salt fractionation and ion exchange chromatography followed by dialysis.
IgM constant region Isotype Control, IGM Isotype Control
Substanzklasse
Antibody
Hintergrund
Immunoglobulin M, or IgM for short, is a basic antibody that is produced by B cells. It is the primary antibody against A and B antigens on red blood cells. IgM is by far the physically largest antibody in the human circulatory system. It is the first antibody to appear in response to initial exposure to antigen. The fragment antigen-binding (Fab fragment) is a region on an antibody that binds to antigens. It is composed of one constant and one variable domain of each of the heavy and the light chain. These domains shape the paratope - the antigen-binding site - at the amino terminal end of the monomer. The two variable domains bind the epitope on their specific antigens.