anti-Hund ube3a Antikörper für Western Blotting

Recommended ube3a Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Ubiquitin Protein Ligase E3A (ube3a) Antikörper
  • ANCR
  • AS
  • E6-AP
  • EPVE6AP
  • HPVE6A
  • DDBDRAFT_0188760
  • DDBDRAFT_0302447
  • DDB_0188760
  • DDB_0302447
  • ube3a
  • im:7140733
  • zgc:92173
  • 4732496B02
  • 5830462N02Rik
  • A130086L21Rik
  • Hpve6a
  • mKIAA4216
  • As
  • CG6190
  • Dmel\\CG6190
  • Dube3a
  • UBE3A
  • dUBE3A
  • das
  • dube3A
  • dube3a
  • MGC69536
  • UME3A
  • ubiquitin protein ligase E3A
  • ubiquitin-protein ligase E3A
  • Ubiquitin protein ligase E3A
  • ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) S homeolog
  • ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome)
  • UBE3A
  • ube3a
  • LOC100194730
  • Ube3a
  • ube3a.S
  • Eint_040430
Epitop
N-Term
15
13
12
10
4
3
3
3
2
2
2
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Yeast (Saccharomyces cerevisiae), Zebrafisch (Danio rerio)
96
47
26
4
3
3
3
3
2
2
2
2
1
1
1
Wirt
Kaninchen
82
14
Klonalität
Polyklonal
Konjugat
Dieser ube3a Antikörper ist unkonjugiert
5
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
80
31
29
16
16
13
9
8
5
3
1
Optionen
Hersteller
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Pubmed
1 Publikation vorhanden

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Western Blotting (WB) image for anti-Ubiquitin Protein Ligase E3A (ube3a) (N-Term) antibody (ABIN2775647)
Western Blotting (WB) image for anti-Ubiquitin Protein Ligase E3A (ube3a) (N-Term) antibody (ABIN2775647)
Produktnummer ABIN2775647
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.252573 ABIN2775648 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
1 ABIN468817 WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN1978618 IP WB Rabbit IgG AA 75-125 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Ubiquitin Protein Ligase E3A (ube3a) Antikörper
Epitop N-Term
(15), (13), (12), (10), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Yeast (Saccharomyces cerevisiae), Zebrafisch (Danio rerio)
(96), (47), (26), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Wirt Kaninchen
(82), (14)
Klonalität
Polyklonal
Konjugat Dieser ube3a Antikörper ist unkonjugiert
(5), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(80), (31), (29), (16), (16), (13), (9), (8), (5), (3), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-ube3a Antikörper

Target Details ube3a Anwendungsinformationen Handhabung Referenzen für anti-ube3a Antikörper (ABIN2775647) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN985847.
Sequenz SLQAKDEDKD EDEKEKAACS AAAMEEDSEA SSSRIGDSSQ GDNNLQKLGP
Homologie Cow: 93%, Dog: 93%, Goat: 90%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Yeast: 91%, Zebrafish: 100%
Produktmerkmale This is a rabbit polyclonal antibody against UBE3A. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human UBE3A

Target Details ube3a

Produktdetails anti-ube3a Antikörper Anwendungsinformationen Handhabung Referenzen für anti-ube3a Antikörper (ABIN2775647) Bilder zurück nach oben
Antigen
Andere Bezeichnung UBE3A (ube3a Antibody Abstract)
Hintergrund UBE3A is an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined.
Alias Symbols: ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A
Protein Interaction Partner: KLHL38, UBE2D1, UBB, TP53, TAT, AFG3L1P, ATG9A, ASAP3, AHSP, UBE3A, UBC, MEOX2, MAGEA8, JADE1, YOD1, UBE2L3, UBE2D3, PSMD14, SHFM1, ARNTL, LPP, HSF1, DR1, BTF3L4, LRSAM1, P3H1, NPLOC4, IPO11, DBNL, LSM1, ARPC1B, METTL1, SACS, ARC, RAD23A, PTPN3, CEBPA, SC
Protein Size: 875
Molekulargewicht 101 kDa
Gen-ID 7337
NCBI Accession NM_000462, NP_000453
UniProt Q05086
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway

Anwendungsinformationen

Produktdetails anti-ube3a Antikörper Target Details ube3a Handhabung Referenzen für anti-ube3a Antikörper (ABIN2775647) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 875 AA
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-ube3a Antikörper Target Details ube3a Anwendungsinformationen Referenzen für anti-ube3a Antikörper (ABIN2775647) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ube3a Antikörper (ABIN2775647)

Produktdetails anti-ube3a Antikörper Target Details ube3a Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Bedard, Underbrink, Howie, Galloway: "The E6 oncoproteins from human betapapillomaviruses differentially activate telomerase through an E6AP-dependent mechanism and prolong the lifespan of primary keratinocytes." in: Journal of virology, Vol. 82, Issue 8, pp. 3894-902, 2008

Bilder

Produktdetails anti-ube3a Antikörper Target Details ube3a Anwendungsinformationen Handhabung Referenzen für anti-ube3a Antikörper (ABIN2775647) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Ubiquitin Protein Ligase E3A (ube3a) (N-Term) antibody (ABIN2775647) WB Suggested Anti-UBE3A Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Ubiquitin Protein Ligase E3A (ube3a) (N-Term) antibody (ABIN2775647) WB Suggested Anti-UBE3A
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 ...