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This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.
LIM domain protein DRAL
, aging-associated gene 11
, down-regulated in rhabdomyosarcoma LIM protein
, four and a half LIM domains protein 2
, skeletal muscle LIM-protein 3
, SLIM 3
, four and a half LIM domains 2