anti-Human Arrestin 3 Antikörper für Immunofluorescence

Recommended Arrestin 3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Arrestin, beta 2 (ARRB2) Antikörper
  • ARRB2
  • arb2
  • arr2
  • arrestin
  • barr2
  • betaarr2
  • ARB2
  • ARR2
  • BARR2
  • BARRES
  • AI326910
  • AW122872
  • arrb2
  • zgc:64007
  • arrestin beta 2
  • arrestin, beta 2
  • arrestin beta 2 L homeolog
  • arrestin, beta 2b
  • ARRB2
  • arrb2
  • Arrb2
  • arrb2.L
  • arrb2b
Epitop
AA 300-410
13
8
7
5
4
4
3
3
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human
99
36
32
8
7
6
5
5
3
2
2
2
1
1
1
1
Wirt
Maus
63
23
13
Klonalität
Monoklonal
Konjugat
Dieser Arrestin 3 Antikörper ist unkonjugiert
5
3
2
1
1
1
Applikation
ELISA, Immunofluorescence (IF), Western Blotting (WB)
86
58
43
28
24
19
5
4
2
2
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN393334
$ 461.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
11.344114 ABIN393344 ELISA IF WB Mouse IgG2a kappa AA 300-410 Anmelden zum Anzeigen 4D2 5
11.344114 ABIN1871114 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
11.344114 ABIN782336 EIA IF IHC (p) WB Mouse IgG2a AA 300-410 Anmelden zum Anzeigen 3G1 0
11.344114 ABIN5962974 IF IHC Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
11.344114 ABIN4281708 ELISA IF IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
11.344114 ABIN513515 IF ELISA WB Mouse IgG2a kappa AA 300-409, partial Anmelden zum Anzeigen 4D2 0
11.344114 ABIN559954 IF PLA ELISA WB Mouse IgG2a kappa AA 300-409, partial Anmelden zum Anzeigen 3G1 0
11.344114 ABIN5075293 ICC IF Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN790451 ELISA IF IHC IHC (p) WB Mouse IgG2a, kappa AA 300-410 Anmelden zum Anzeigen 3G1 0
1 ABIN439120 ICC IF IHC (p) IHC WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN4901011 IF WB Mouse C-Term Anmelden zum Anzeigen 0
1 ABIN5945256 ICC IF IHC IHC (p) Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN2477635 IF WB Mouse IgG2a AA 300-410 Anmelden zum Anzeigen 4D2 0
1 ABIN2879675 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN5660721 IC IF WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN2471352 IF IHC ELISA WB Mouse IgG2a kappa AA 300-410, partial Anmelden zum Anzeigen 3G1 0
1 ABIN1723810 IF IHC (p) ELISA WB Mouse IgG2a kappa AA 300-410 Anmelden zum Anzeigen 3G1 0
1 ABIN1976804 IF IHC IHC (p) IP WB Rabbit IgG AA 355-405 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1976803 IF IHC IHC (p) IP Rabbit IgG AA 310-360 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2694301 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0

General

Antigen Arrestin, beta 2 (ARRB2) Antikörper
Epitop AA 300-410
(13), (8), (7), (5), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(99), (36), (32), (8), (7), (6), (5), (5), (3), (2), (2), (2), (1), (1), (1), (1)
Wirt Maus
(63), (23), (13)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser Arrestin 3 Antikörper ist unkonjugiert
(5), (3), (2), (1), (1), (1)
Applikation ELISA, Immunofluorescence (IF), Western Blotting (WB)
(86), (58), (43), (28), (24), (19), (5), (4), (2), (2), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Arrestin 3 Antikörper

Target Details Arrestin 3 Anwendungsinformationen Handhabung Referenzen für anti-Arrestin 3 Antikörper (ABIN393334) Bilder
Spezifität ARRB2 (AAH07427, 300 a.a. ~ 410 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Kreuzreaktivität (Details) Human: ~~ Positive
Reinigung This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen

Antigen Type: Recombinant Protein

Target/Specificity: ARRB2 (AAH07427, 300 a.a. ~ 409 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon 3G1
Isotyp IgG2a kappa
Plasmids, Primers & others

Target Details Arrestin 3

Produktdetails anti-Arrestin 3 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Arrestin 3 Antikörper (ABIN393334) Bilder zurück nach oben
Antigen
Andere Bezeichnung ARRB2 (ARRB2 Antibody Abstract)
Hintergrund

Other Names: Beta-arrestin-2, Arrestin beta-2, ARRB2, ARB2, ARR2

Gene Description: arrestin, beta 2

Gene Summary: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq

Molekulargewicht 46106 DA
Gen-ID 409
NCBI Accession NP_001244257, NP_001244258, NP_001244259, NP_001244260, NP_004304, NP_945355
UniProt P32121
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling

Anwendungsinformationen

Produktdetails anti-Arrestin 3 Antikörper Target Details Arrestin 3 Handhabung Referenzen für anti-Arrestin 3 Antikörper (ABIN393334) Bilder zurück nach oben
Applikations-hinweise Western blot = 1:500-1000
Kommentare

Background: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Arrestin 3 Antikörper Target Details Arrestin 3 Anwendungsinformationen Referenzen für anti-Arrestin 3 Antikörper (ABIN393334) Bilder zurück nach oben
Buffer Clear, colorless solution in phosphate buffered saline,  pH 7.2 .
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Haltbarkeit 6 months

Referenzen für anti-Arrestin 3 Antikörper (ABIN393334)

Produktdetails anti-Arrestin 3 Antikörper Target Details Arrestin 3 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Oneda, Crettol, Bochud, Besson, Croquette-Krokar, Hämmig, Monnat, Preisig, Eap: "β-Arrestin2 influences the response to methadone in opioid-dependent patients." in: The pharmacogenomics journal, Vol. 11, Issue 4, pp. 258-66, 2011

Li, Sun, LeSage, Zhang, Liang, Chen, Hanley, He, Sun, Yin: "β-arrestin 2 regulates Toll-like receptor 4-mediated apoptotic signalling through glycogen synthase kinase-3β." in: Immunology, Vol. 130, Issue 4, pp. 556-63, 2010

Bousman, Glatt, Cherner, Atkinson, Grant, Tsuang, Everall,: "Preliminary evidence of ethnic divergence in associations of putative genetic variants for methamphetamine dependence." in: Psychiatry research, Vol. 178, Issue 2, pp. 295-8, 2010

Kuhr, Zhang, Brovkovych, Skidgel: "Beta-arrestin 2 is required for B1 receptor-dependent post-translational activation of inducible nitric oxide synthase." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 7, pp. 2475-83, 2010

Shankar, Michal, Kern, Kang, Gurevich, Benovic: "Non-visual arrestins are constitutively associated with the centrosome and regulate centrosome function." in: The Journal of biological chemistry, Vol. 285, Issue 11, pp. 8316-29, 2010

Bilder

Produktdetails anti-Arrestin 3 Antikörper Target Details Arrestin 3 Anwendungsinformationen Handhabung Referenzen für anti-Arrestin 3 Antikörper (ABIN393334) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Arrestin, beta 2 (ARRB2) (AA 300-410) antibody (ABIN393334) Western Blot analysis of ARRB2 expression in transfected 293T cell line by ARRB2 mono...
Immunohistochemistry (IHC) image for anti-Arrestin, beta 2 (ARRB2) (AA 300-410) antibody (ABIN393334) anti-Arrestin, beta 2 (ARRB2) (AA 300-410) antibody (Image 2)
Western Blotting (WB) image for anti-Arrestin, beta 2 (ARRB2) (AA 300-410) antibody (ABIN393334) Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunoge...
Western Blotting (WB) image for anti-Arrestin, beta 2 (ARRB2) (AA 300-410) antibody (ABIN393334) Western Blot analysis of ARRB2 expression in transfected 293T cell line by ARRB2 mono...
Immunofluorescence (IF) image for anti-Arrestin, beta 2 (ARRB2) (AA 300-410) antibody (ABIN393334) Immunofluorescence of monoclonal antibody to ARRB2 on HeLa cell . [antibody concentra...
ELISA image for anti-Arrestin, beta 2 (ARRB2) (AA 300-410) antibody (ABIN393334) Detection limit for recombinant GST tagged ARRB2 is approximately 0.03ng/ml as a capt...
 image for anti-Arrestin, beta 2 (ARRB2) (AA 300-410) antibody (ABIN393334) Proximity Ligation Analysis of protein-protein interactions between MAPK3 and ARRB2. ...