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anti-Mouse (Murine) TEP1 Antikörper:
anti-Rat (Rattus) TEP1 Antikörper:
anti-Human TEP1 Antikörper:
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inhibition of PTEN by Notch1/Hes1 in response to high glucose concentration inhibits autophagy, which is associated with the progression of fibrosis in diabetic nephropathy
A Smad3 (zeige SMAD3 Antikörper)-PTEN regulatory loop controls proliferation and apoptotic responses to TGF-beta (zeige TGFB1 Antikörper) in mouse endometrium.
Here, we provide novel insights into treatment response for the antiandrogen abiraterone by analyses of a genetically engineered mouse (GEM) model with combined inactivation of Trp53 and Pten, which are frequently comutated in human castration-resistant prostate cancer (CRPC).
Pten is required for proamniotic cavity formation by establishing polarity for epiblast cells to form a rosette that expands into the proamniotic lumen, rather than facilitating apoptosis to create the cavity
Here, we show that cabozantinib rapidly eradicates invasive, poorly differentiated PTEN/p53 (zeige TP53 Antikörper)-deficient murine prostate cancer. This was associated with enhanced release of neutrophil chemotactic factors from tumor cells, including CXCL12 (zeige CXCL12 Antikörper) and HMGB1 (zeige HMGB1 Antikörper), resulting in robust infiltration of neutrophils into the tumor.
Here we show that radiation-resistant cells and tumors derived from a Pten/Trp53 (zeige TP53 Antikörper)-deficient mouse model of advanced prostate cancer are rendered radiation sensitive following treatment with NanoOlaparib, a lipid-based injectable nanoformulation of olaparib.
CaMKII (zeige CAMK2G Antikörper) is a target of PTENalpha phosphatase and that PTENalpha is an essential element in the molecular regulation of neural activity.
PTEN-beta-catenin (zeige CTNNB1 Antikörper) signaling is a novel regulator involved in modulating Treg development and may lead to a potential therapeutic target in liver ischemia/reperfusion injury
Loss of PTEN expression is associated with ovarian tumor cells originating in the fallopian tube stroma.
The mice of Mutan of pten showed the neurons of brain exhibit excessive PI3K/Akt (zeige AKT1 Antikörper)/mTOR (zeige FRAP1 Antikörper) signaling activity, enlarged somas and increased dendritic arborization.
The current results suggested that genetic variants at TEP1 SNPs rs1760893 and rs1713423 may be associated significantly with increased risk of stomach cancer.
TEP1 Polymorphisms are not associated with Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B Virus Infection.
These data suggest that genetic variations in the TEP1 gene may be biomarkers for risk of PCa (zeige FLVCR1 Antikörper) and BCR (zeige BCR Antikörper) after RP.
8 common SNPs in telomerase reverse transcriptase (TERT (zeige TERT Antikörper)) and telomerase-associated protein 1 (TEP1) were genotyped.
the protein levels of MVP (zeige MVP Antikörper), TEP1 and vPARP (zeige PARP4 Antikörper) are actually increased in the highergrade tumors suggesting existence of post-transcriptional regulation of vault component production.
TP1 (zeige RPLP2 Antikörper) expression did not change after cisplatin exposure for 72 hours.
TEP1, hTR (zeige F2R Antikörper), hsp90 (zeige HSP90 Antikörper), p23, and dyskerin (zeige DKC1 Antikörper) remained at high and unchanged levels throughout up- or down regulation of telomerase activity.
TEP1, TOPOIIalpha, and HSP90 (zeige HSP90 Antikörper) interact directly with BLM (zeige BLM Antikörper) in vitro and modulate its helicase activity on telomere-like DNA substrates but not on non-telomeric substrates.
This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans.
mutated in multiple advanced cancers 1
, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
, protein tyrosine phosphatase and tensin-like protein
, phosphatase and tensin homolog deleted on chromosome ten
, telomerase protein component 1
, telomerase protein 1
, p80 telomerase homolog
, telomerase-associated protein 1
, p80 homolog
, TROVE domain family, member 1