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KCNQ1 (zeige KCNQ1 ELISA Kits), KCNE2 (zeige KCNE2 ELISA Kits), and SMIT1 form reciprocally regulating complexes that affect neuronal excitability.
activation of NFAT5 (zeige NFAT5 ELISA Kits) and its downstream SMIT induction is important in protecting neurons from ischemia-induced oxidative stress
At low concentration, where SMIT1/2 activity gains importance, myo (zeige SYNPO2 ELISA Kits)-inositol uptake is reduced by ammonia-induced intracellular acidification
These findings add Mus (zeige TRPV6 ELISA Kits) spicilegus endogenous retrovirus HEMV as a second member to the murine leukemia virus subgroup that uses mSMIT1 to gain entry into cells.
brain SMIT1 levels were higher than SMIT2, however, regional differences were observed
Sodium/MI cotransporter 1 (SMIT1, the major cotransporter of MI) knockout (SMIT1(-/-)) mice with markedly reduced tissue myoinositol (MI) levels were used to characterize the essential roles of MI and SMIT1 in osteogenesis.
SLC5a3 is responsible for the Ins (zeige INS ELISA Kits) concentration gradient in the murine fetal-placental unit
used by Mus (zeige TRPV6 ELISA Kits) cervicolor Murine Leukemia Virus for cell entry
When Sertoli cells were cultured in a hypertonic medium, there was an increase in the expression of Isyna1 (zeige ISYNA1 ELISA Kits) and Slc5a3
SMIT-1 has a role in the development and function of the peripheral nerves
SMIT1 Modifies KCNQ (zeige KCNQ1 ELISA Kits) Channel Function and Pharmacology by Physical Interaction with the Pore
overexpression of the Na(+)/myo-inositol cotransporter (SMIT1) and myo (zeige SYNPO2 ELISA Kits)-inositol supplementation enlarged intracellular PI(4,5)P2 pools, modulated several PI(4,5)P2-dependent ion channels including KCNQ2 (zeige KCNQ2 ELISA Kits)/3 channels, and attenuated the action potential firing of superior cervical ganglion neurons
Hypotonic stress causes a significant upregulation of SLC5A3 gene expression as detected by semiquantitative RT-PCR and Western blot analysis.
A kinetic model has been generated for the transport mechanism of SMIT2 allowing insight into the transport of members of the LeuT structural family at the millisecond timescale.
JAK2 (zeige JAK2 ELISA Kits) contributes to the regulation of the myoinositol transporter SMIT.
Tumor cells silence SLC5A8 (zeige SLC5A8 ELISA Kits) and convert pyruvate into lactate as complementary mechanisms to avoid pyruvate-induced cell death.
Expression and/or function of SMIT2 may be reduced in diabetes mellitus, insulin (zeige INS ELISA Kits) resistance and polycystic ovary syndrome causing abnormal inositol meteabolism
Functions as a retroviral receptor for M813 murine leukemia virus (MuLV) entry. Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function.
, sodium myo-inositol transporter 1
, sodium/myo-inositol cotransporter
, sodium/myo-inositol transporter 1
, solute carrier family 5 member 3
, solute carrier family 5, member 3
, solute carrier family 5, member alpha 3
, BCW2 protein
, human solute carrier family 5, member 3, Sodium/myo-inositol cotransporter
, sodium/myo-inositol cotransporter 1
, solute carrier family 5 (inositol transporter), member 3
, solute carrier family 5 (inositol transporters), member 3
, osmoregulatory Na+/myo-inositol cotransporter