Details zu Produkt Nr. ABIN3220297
Inhibition Assay (InhA), Functional Studies (Func)
Verwendungszweck BX795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, 140- and 1600-fold more selective for PDK1 than PKA and PKC in cell-free assays, respectively. Meanwhile, in comparison to GSK3β more than 100-fold selectivity observed for PDK1.
Produktmerkmale Target: PDK inhibitor,c-Kit inhibitor, CDK inhibitor, PKA inhibitor
Receptor: PDE1/TBK1,c-kit,CDK2,PKA
Reinigung All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Reinheit 98 %
Formel C23H26IN7O2S
Löslichkeit DMSO > 100mM
Hintergrund Cell Cycle/Checkpoint,PI3K/Akt/mTOR Signaling,Tyrosine Kinase/Adaptors
Molekulargewicht 591.47 g/mol
CAS-Nummer 702675-74-9
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Solid
Lagerung -20 °C
Informationen zur Lagerung For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Haltbarkeit 24 months