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AT13148

InhA, Func 1056901-62-2
Produktnummer ABIN3220128
  • Applikation
    Inhibition Assay (InhA), Functional Studies (Func)
    Verwendungszweck
    AT13148 is an oral, ATP-competitive, multi-AGC kinase inhibitor with IC50 of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively. Phase 1.
    Produktmerkmale
    Target: Akt inhibitor, ROCK inhibitor,S6 Kinase inhibitor, PKA inhibitor
    Receptor: PKA,ROCK2,ROCK1,p70S6K,Akt1,Akt3,SGK3,RSK1,Akt2
    Aufreinigung
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    Reinheit
    97 % +
    Formel
    C17H16ClN3O
    Löslichkeit
    200 mM in DMSO
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Solid
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    Haltbarkeit
    24 months
  • Hintergrund
    PI3K/Akt/mTOR Signaling
    Molekulargewicht
    313.78 g/mol
    CAS-Nummer
    1056901-62-2
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