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anti-Human Interleukin 6 Antikörper:
anti-Mouse (Murine) Interleukin 6 Antikörper:
anti-Rat (Rattus) Interleukin 6 Antikörper:
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Human Monoclonal Interleukin 6 Primary Antibody für FACS - ABIN1383944
Lu, Brochier, Wijdenes, Brailly, Bataille, Klein: High amounts of circulating interleukin (IL)-6 in the form of monomeric immune complexes during anti-IL-6 therapy. Towards a new methodology for measuring overall cytokine production in human in vivo. in European journal of immunology 1992
Show all 60 Pubmed References
Mouse (Murine) Polyclonal Interleukin 6 Primary Antibody für WB - ABIN3042620
Xu, Feng, Wang, Zhu, Lin, Lou, Xiang, He, Zheng, Tang, Zuo: Phytoestrogen calycosin-7-O-?-D-glucopyranoside ameliorates advanced glycation end products-induced HUVEC damage. in Journal of cellular biochemistry 2011
Show all 29 Pubmed References
Mouse (Murine) Polyclonal Interleukin 6 Primary Antibody für ELISA, WB - ABIN3043248
Liu, Shan, Dong, Liu, Ma, Liu: Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury. in World journal of gastroenterology 2013
Show all 27 Pubmed References
Human Polyclonal Interleukin 6 Primary Antibody für WB - ABIN3043090
Qin, Ma, Yang, Hu, Zhou, Fu, Tian, Liu, Xu, Shen: A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes. in Natural products and bioprospecting 2015
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Rat (Rattus) Polyclonal Interleukin 6 Primary Antibody für WB - ABIN3042526
Shi, Song, Zhang, Li, Li: Correlation between the microinflammatory state and left ventricular structural and functional changes in maintenance haemodialysis patients. in Experimental and therapeutic medicine 2013
Show all 27 Pubmed References
Human Polyclonal Interleukin 6 Primary Antibody für WB - ABIN3042806
Chen, Zhao, Wu, Zou, Luo, Li, Xie, Liang: The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice. in International journal of clinical and experimental pathology 2015
Show all 21 Pubmed References
Mouse (Murine) Polyclonal Interleukin 6 Primary Antibody für ELISA, WB - ABIN5693120
Wan, Ma, Mei, Shan: The effects of HIF-1alpha on gene expression profiles of NCI-H446 human small cell lung cancer cells. in Journal of experimental & clinical cancer research : CR 2010
Show all 12 Pubmed References
Human Polyclonal Interleukin 6 Primary Antibody für ICC, IF - ABIN269335
Bottino, Balamurugan, Tse, Thirunavukkarasu, Ge, Profozich, Milton, Ziegenfuss, Trucco, Piganelli: Response of human islets to isolation stress and the effect of antioxidant treatment. in Diabetes 2004
Show all 14 Pubmed References
Human Monoclonal Interleukin 6 Primary Antibody für CyTOF, FACS - ABIN4900155
Maneechotesuwan, Wamanuttajinda, Kasetsinsombat, Huabprasert, Yaikwawong, Barnes, Wongkajornsilp: Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma. in The Journal of allergy and clinical immunology 2009
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Mouse (Murine) Polyclonal Interleukin 6 Primary Antibody für IF (p), IHC (p) - ABIN728083
Sun, Zeng, Cao, Song, Zhang, Liu: Vibration Training Triggers Brown Adipocyte Relative Protein Expression in Rat White Adipose Tissue. in BioMed research international 2015
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LL was significantly negatively correlated with PGC-1alpha, TNF-alpha, and IL-6 mRNA expressions. PGC-1alpha mRNA expression levels in paraspinal muscles may be affected by lumbar kyphosis.
Study found that IL-6 and IL-8 (zeige IL8 Antikörper) are necessary and sufficient to increase tumor cell migration in a cell density dependent manner with negligible feedback on cell proliferation. This effect is specific to metastatic cancer cells; IL-6 and IL-8 (zeige IL8 Antikörper) have no effect on the migration of normal and non-metastatic cancer cells.
Rheumatoid arthritis patients who had the best response to tocilimuzab had the highest levels of IL6 and the lowest levels of soluble IL6 receptor.
High IL6 expression is associated with retinopathy of prematurity.
Adult serum IL-6 levels were predicted across periods as long as 15 years by adolescents' inability to defuse peer aggression and poor peer-rated conflict resolution skills, and by independently observed romantic partner hostility in late adolescence.
Lysophosphatidylcholine induces COX-2 (zeige COX2 Antikörper)-mediated IL-6 expression. NADPH oxidase (zeige NOX1 Antikörper)/Reactive Oxygen Species is involved in Lysophosphatidylcholine-induced COX-2 (zeige COX2 Antikörper) expression.
The expression of IL-6 gene and protein was significantly induced by IL-17F (zeige IL17F Antikörper). IL-17F (zeige IL17F Antikörper) activated TAK1 (zeige MAP3K7 Antikörper) and NF-kappaB (zeige NFKB1 Antikörper) in airway smooth muscle cells.
IL-6 was over-expressed in SF from OA patients compared with normal donors. DNA hypomethylation and histone hyperacetylation were observed in the IL-6 promoter region in OA SF compared with normal SF. No differences in the status of H3K9 di-methylation, H3K27 tri (zeige VANGL2 Antikörper)-methylation and H3K4 tri (zeige VANGL2 Antikörper)-methylation in the IL-6 promoter region were observed between normal and OA SF.
Increased serum IL6 concentrations are associated with obstructive sleep apnea and glycemic status.
Study showed that activation of NF-kappaB (zeige NFKB1 Antikörper)/IL-6 is involved in moderate hyperthermia treatment induced progression of hepatocellular carcinoma cells.
In macrophages, SCIMP (zeige SCIMP Antikörper) is constitutively associated with the Lyn (zeige LYN Antikörper) tyrosine kinase (zeige TYRO3 Antikörper), is required for tyrosine phosphorylation of TLR4 (zeige TLR4 Antikörper), and facilitates TLR-inducible production of the IL-6 and IL-12p40.
data revealed that IL-6 regulates the excessive release of NO through IL-1beta (zeige IL1B Antikörper) inhibition and determines the establishment of an M2 macrophage profile within infected heart tissue.
IL-6 plays a role in consolidation process.
IL-6 expands dendritic cell and monocytic populations and ultimately leads to a robust T-cell driven immune response in Complete Freund's Adjuvant immunized mice.
These results suggested that the thrombinstimulated synthesis of IL6 was limited by HSP90 (zeige HSP90 Antikörper) in osteoblasts, and that the effects of HSP90 (zeige HSP90 Antikörper) were exerted at the point between Rhokinase and p38 MAPK (zeige MAPK14 Antikörper).
Results suggest that interleukin 6 (IL-6) may be exploited for lung repair during influenza infection.
YY1 (zeige YY1 Antikörper) was progressively up-regulated in BV2 (zeige DNAH9 Antikörper) microglial cells stimulated with lipopolysaccharide (LPS (zeige TLR4 Antikörper)), which was dependent on the transactivation function of nuclear factor kappa B (NF-kappaB (zeige NFKB1 Antikörper)). Furthermore, YY1 (zeige YY1 Antikörper) knockdown notably inhibited LPS (zeige TLR4 Antikörper)-induced the activation of NF-kappaB (zeige NFKB1 Antikörper) signaling and interleukin-6 (IL-6) expression in BV-2cells.
The authors conclude that Mycobacterium tuberculosis ESAT-6 stimulates macrophage IL-6 production through STAT3 (zeige STAT3 Antikörper) activation.
IL-6/soluble IL-6R differentially regulate RANKL (zeige TNFSF11 Antikörper)-induced osteoclast differentiation and activity through modulation of NF-kappaB (zeige NFKB1 Antikörper), ERK (zeige EPHB2 Antikörper) and JNK (zeige MAPK8 Antikörper) signaling pathways.
These results suggest that the inhibition of IL6/STAT3 (zeige STAT3 Antikörper) signaling is a potential mechanism by which PZH is used in the treatment of ulcerative colitis.
Mild heat shock increased the production of inflammatory cytokines, IL-1beta (zeige IL1B Antikörper) and IL-6 in rabbit cornea cells.
These data suggest that IL-6 may play a key role in equine metabolic syndrome (EMS), and that pro-inflammatory cytokines levels in serum may serve as an additional tool for diagnosing EMS.
IL-6 stimulation decreased chondrocyte expression of the canonical Wnt (zeige WNT2 Antikörper) signaling pathway transactivator beta-catenin (zeige CTNNB1 Antikörper), induced expression of inhibitors of the Wnt (zeige WNT2 Antikörper) pathway, and increased expression of GDF-5 (zeige GDF5 Antikörper).
study shows that IL-6 is rapidly induced in BAL-cells of airway-compromised horses in response to adenosine exposure, probably through A2BAR (zeige ADORA2B Antikörper) activation and that this effect can be modulated by A2AAR (zeige ADORA2A Antikörper)
Our data show the presence of a polymorphism downstream of the equine IL-6 gene that is associated with the basal Cu:Zn ratio in horses independent of breed.
Expression levels of IL-6 are significantly increased in peripheral blood mononuclear cells from trained horses compared to sedentary animals.
Failure of passive transfer may directly influence the serum IL-6 concentration in septic foals. Neither serum IL-6 nor IL-10 (zeige IL10 Antikörper) alone, were useful diagnostic indices of sepsis in equine neonates.
The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6, IL-10 (zeige IL10 Antikörper) and TNF-alpha (zeige TNF Antikörper), in horses with recurrent airway obstruction during exacerbation and in remission is reported.
The role of IL-6 and its signaling pathway in enhancing colonic proliferation.Il-6 is a key regulator of chronic intestinal inflammation.
we showed that IL-6 did not directly promote the proliferation of theca interna cells.
Induction of ischemic osteonecrosis results in IL-6 production in the articular cartilage through an HIF-1 (zeige HIF1A Antikörper)-dependent pathway. IL-6 produced by hypoxic articular chondrocytes stimulates inflammatory cytokine responses in synovial cells.
The effects of semen, spermatozoa in extender, or extender alone on the expression of TGF-beta1 (zeige TGFB1 Antikörper), IL-10 (zeige IL10 Antikörper), and IL-6 in ovarian follicles are reported.
Data suggest IL6 prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst viability via IL6/STAT3 (zeige STAT3 Antikörper) (signal transducer/activator of transcription (zeige STAT1 Antikörper) 3) signaling pathway (including up-regulation of STAT3 (zeige STAT3 Antikörper) expression/phosphorylation).
LIF (zeige LIF Antikörper) and IL-6 are important components of embryo-uterine interactions during early pregnancy in the pig, and may contribute to successful conceptus implantation.
INFgamma and IL-6 modulate PPARs gene expression in the porcine endometrium during the estrous cycle and pregnancy.
IL-6 was low or undetectable in Boar seminal plasma.
interleukin-6, endothelin ET-1 (zeige EDN1 Antikörper), and apoptotic Bak (zeige BAK1 Antikörper) and Bcl-XL (zeige BCL2L1 Antikörper) genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury
Data show that all five molecules, BNP (zeige BNC2 Antikörper), ICAM-1 (zeige ICAM1 Antikörper), TNF-alpha (zeige TNF Antikörper), VCAM-1 (zeige VCAM1 Antikörper) and IL-6, quickly and reliably signaled adverse interactions.
STA3 (zeige ARHGEF3 Antikörper) facilitates TLR4 (zeige TLR4 Antikörper)-dependent IL-6 and IL-8 (zeige IL8 Antikörper) production via IL-6 receptor-positive feedback in endometrial cells.
when a confluent endometrial epithelial cell barrier is faced with infection and damage, chemokines attract immune cells to the uterine lumen, but IL6 is solely secreted apically to ensure immune cells are only exposed to IL6 once they reach the lumen.
The results revealed that the peak expression of IL6 and 21 was on DPV 28 which correlated well with the FMDV antibody titer and plummeted to the prevaccination titer level by 60 DPV.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (zeige IL8 Antikörper) and PTGS2 (zeige PTGS2 Antikörper), and decreased the expression of SOD2 (zeige SOD2 Antikörper), GPX3 (zeige GPX3 Antikörper), DAB2 (zeige DAB2 Antikörper), and NR3C1 (zeige NR3C1 Antikörper). TNF (zeige TNF Antikörper) and IL6 levels were also decreased while those of NAMPT (zeige NAMPT Antikörper) were unaffected.
Testicular IL-1 alpha (zeige IL1A Antikörper) and IL-1 beta (zeige IL1B Antikörper) concentrations were highest in the early post-natal period; however, IL-1 (zeige IL1A Antikörper) bioactivity and IL-6 concentrations were greatest in the immediate pre-pubertal period.
The results showed that the expression of TNF-alpha (zeige TNF Antikörper), iNOS (zeige NOS2 Antikörper), and IL-6 in alveolar macrophages was up-regulated by stimulation with the recombinant Mce4A protein of M. bovis; in contrast, expression of IL-12 (zeige IL12A Antikörper) was unaffected.[IL-6, IL-12 (zeige IL12A Antikörper)]
results show for the first time that interleukin-6 (IL6), in the presence of its soluble receptor (zeige IFNAR1 Antikörper) (sIL (zeige STIL Antikörper)-6R), induces activation of JAK1 (zeige JAK1 Antikörper), JAK2 (zeige JAK2 Antikörper), and STAT1 (zeige STAT1 Antikörper)/STAT3 (zeige STAT3 Antikörper) proteins in bovine articular chondrocytes.
Mechanical injury potentiates the catabolic effects of TNFalpha (zeige TNF Antikörper) and IL-6/sIL (zeige STIL Antikörper)-6R in causing proteoglycan (zeige Vcan Antikörper) degradation in human and bovine cartilage.
Plasma nitric oxide acts as a regulator of cytokine function exhibiting negative feedback to maintain steady plasma IL-6 concentration in protein- or energy-restricted goats during late gestation.
The results reveal that, in trout, IL-6 is a differentiation factor for B cells, stimulating IgM responses in the absence of follicular structures, and suggest that it was after follicular structures appeared that this cytokine evolved to modulate T-dependent responses within the germinal centers.
IL6 mRNA abundance was significantly increased in spleen, liver, and gill of rainbow trout after experimental infection with Aeromonas salmonicida.
in this paper we present for the first time in fish the functional characterisation of IL-6, using rainbow trout
found that peptidoglycans derived from Gram-negative bacteria (Escherichia coli 0111:B4 and K12 (zeige KRT12 Antikörper)), are potent inducers of IL-1beta (zeige IL1B Antikörper) and IL-6 gene expression and were equal to, or more potent than, crude LPS (zeige IRF6 Antikörper).
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.
B-cell differentiation factor
, B-cell stimulatory factor 2
, CTL differentiation factor
, hybridoma growth factor
, interferon beta-2
, interleukin BSF-2
, B-cell hybridoma growth factor
, interleukin HP-1
, Interleukin 6 (interferon, beta 2)
, interleukin-6 protein
, interleukin 6 (interferon, beta 2)