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Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validierenRelevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
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14.5 | ABIN3043230 | IHC (p) WB | Rabbit | IgG | AA 203-218, N-Term | Anmelden zum Anzeigen | Polyclonal | 1 | ||
12.136095 | ABIN1689928 | ICC IHC (p) WB | Rabbit | Anmelden zum Anzeigen | Polyclonal | 0 | ||||
11.712328 | ABIN1109100 | IF IHC (p) WB | Rabbit | IgG | N-Term | Anmelden zum Anzeigen | Polyclonal | 0 | ||
7 | ABIN225218 | IHC IHC (p) WB | Rabbit | IgG | N-Term | Anmelden zum Anzeigen | Polyclonal | 0 | ||
1 | ABIN600206 | ICC IHC IHC (p) WB | Rabbit | IgG | N-Term | Anmelden zum Anzeigen | Polyclonal | 0 | ||
1 | ABIN2628273 | IHC IHC (p) WB | Rabbit | IgG | AA 203-218 | Anmelden zum Anzeigen | Polyclonal | 0 | ||
1 | ABIN731117 | IHC (p) WB | HRP | Rabbit | IgG | AA 20-70 | Anmelden zum Anzeigen | Polyclonal | 0 | |
1 | ABIN731110 | IHC (p) WB | Biotin | Rabbit | IgG | AA 20-70 | Anmelden zum Anzeigen | Polyclonal | 0 | |
1 | ABIN6242830 | FACS IF IHC (p) WB | Rabbit | Ig Fraction | AA 58-91, N-Term | Anmelden zum Anzeigen | Polyclonal | 0 | ||
0.658 | ABIN4355160 | ICC IF IHC IHC (p) WB | Rabbit | AA 1-75, N-Term | Anmelden zum Anzeigen | Polyclonal | 1 | |||
-12.842 | ABIN4355159 | ICC IF IHC IHC (p) WB | Rabbit | AA 1-75, N-Term | Anmelden zum Anzeigen | Polyclonal | 0 |
General |
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Antigen | Sonic Hedgehog (SHH) Antikörper |
Epitop | AA 20-70 Alternativen |
Reaktivität | Human, Maus, Ratte (Rattus) Alternativen |
Wirt | Kaninchen Alternativen |
Klonalität | |
Konjugat | Dieser Sonic Hedgehog Antikörper ist unkonjugiert Alternativen |
Applikation |
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternativen
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8 Publikationen vorhanden |
Hersteller | Anmelden zum Anzeigen |
Produktdetails anti-Sonic Hedgehog AntikörperTarget Details Sonic Hedgehog Anwendungsinformationen Handhabung Referenzen für anti-Sonic Hedgehog Antikörper (ABIN731108) Bilder |
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Reinigung | Purified by Protein A. |
Immunogen | KLH conjugated synthetic peptide derived from human Shh |
Isotyp | IgG |
Plasmids, Primers & others | |
Target Details Sonic HedgehogProduktdetails anti-Sonic Hedgehog Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Sonic Hedgehog Antikörper (ABIN731108) Bilder zurück nach oben |
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Antigen | |
Andere Bezeichnung | Shh (SHH Antibody Abstract) |
Hintergrund |
Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity). Subcellular location: Cell membrane Synonyms: TPT, HHG1, HLP3, HPE3, SMMCI, TPTPS, MCOPCB5, Sonic hedgehog protein, SHH, HHG-1 |
Gen-ID | 6469 |
UniProt | Q15465 |
Pathways | Hedgehog Signalweg, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development |
AnwendungsinformationenProduktdetails anti-Sonic Hedgehog Antikörper Target Details Sonic Hedgehog Handhabung Referenzen für anti-Sonic Hedgehog Antikörper (ABIN731108) Bilder zurück nach oben |
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Applikations-hinweise |
WB 1:100-1000 IHC-P 1:100-500 IF(IHC-P) 1:50-200 |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails anti-Sonic Hedgehog Antikörper Target Details Sonic Hedgehog Anwendungsinformationen Referenzen für anti-Sonic Hedgehog Antikörper (ABIN731108) Bilder zurück nach oben |
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Format | Liquid |
Konzentration | 1 μg/μL |
Buffer | Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide. |
Konservierungs-mittel | Sodium azide |
Vorsichtsmaßnahmen | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. |
Lagerung | -20 °C |
Informationen zur Lagerung | Store at -20°C |
Haltbarkeit | 12 months |
Referenzen für anti-Sonic Hedgehog Antikörper (ABIN731108)Produktdetails anti-Sonic Hedgehog Antikörper Target Details Sonic Hedgehog Anwendungsinformationen Handhabung Bilder zurück nach oben |
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Produkt verwendet in: |
Yang, Wu, Feng, Huang, Liu, Liu, Chen: "Vitamin C plus hydrogel facilitates bone marrow stromal cell-mediated endometrium regeneration in rats." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 267, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human). Wang, Zhang, Bai, Wang, Du: "Baicalin Attenuates Alcoholic Liver Injury through Modulation of Hepatic Oxidative Stress, Inflammation and Sonic Hedgehog Pathway in Rats." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 39, Issue 3, pp. 1129-40, 2016 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: liver Bai, Lu, Lin, Xu, Hu, Liang, Hong, Chen: "Sonic hedgehog-mediated epithelial-mesenchymal transition in renal tubulointerstitial fibrosis." in: International journal of molecular medicine, Vol. 37, Issue 5, pp. 1317-27, 2016 Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: kidney Wu, Zhao, Cheng, Yang, Huang, Meng, Wu, Zhang, Lv, Li: "Melittin induces PTCH1 expression by down-regulating MeCP2 in human hepatocellular carcinoma SMMC-7721 cells." in: Toxicology and applied pharmacology, Vol. 288, Issue 1, pp. 74-83, 2015 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human). Ma, Li, Li, Yang, Huang, Meng, Zhang, Li: "Geniposide alleviates inflammation by suppressing MeCP2 in mice with carbon tetrachloride-induced acute liver injury and LPS-treated THP-1 cells." in: International immunopharmacology, 2015 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human). Fan, Wang, Zhao, Liu, Chen, Sun, Zheng: "Sonic hedgehog signaling may promote invasion and metastasis of oral squamous cell carcinoma by activating MMP-9 and E-cadherin expression." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 7, pp. 41, 2014 Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human). Weiss, Guo, Shan, Shi, Romano, Sinha, Cantley, Guo: "Brg1 determines urothelial cell fate during ureter development." in: Journal of the American Society of Nephrology : JASN, Vol. 24, Issue 4, pp. 618-26, 2013 Du, Feng, Wang, Piao, Cui, Chen, Lei, Sun, Liu, Wang, Li, Yang, Sun, Zhao, Jiang, Li, Jiang: "Curcumin suppresses malignant glioma cells growth and induces apoptosis by inhibition of SHH/GLI1 signaling pathway in vitro and vivo." in: CNS neuroscience & therapeutics, Vol. 19, Issue 12, pp. 926-36, 2013 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human). |
BilderProduktdetails anti-Sonic Hedgehog Antikörper Target Details Sonic Hedgehog Anwendungsinformationen Handhabung Referenzen für anti-Sonic Hedgehog Antikörper (ABIN731108) zurück nach oben |
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Bilder des Herstellers |
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