anti-Human Sonic Hedgehog Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended Sonic Hedgehog Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Sonic Hedgehog (SHH) Antikörper
  • shh
  • SHH
  • 9530036O11Rik
  • Dsh
  • Hhg1
  • Hx
  • Hxl3
  • M100081
  • HHG1
  • HLP3
  • HPE3
  • MCOPCB5
  • SMMCI
  • TPT
  • TPTPS
  • Xhh
  • hedgehog
  • xshh
  • fc83d08
  • syu
  • vhh-1
  • vhh1
  • wu:fc83d08
  • sonic hedgehog
  • sonic hedgehog protein A
  • sonic hedgehog L homeolog
  • sonic hedgehog a
  • shh
  • SHH
  • Shh
  • shh.L
  • shha
Epitop
AA 20-70
17
14
9
7
5
5
5
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
107
75
59
8
6
5
5
2
2
2
2
2
1
1
1
1
1
1
1
Wirt
Kaninchen
93
41
10
1
Klonalität
Polyklonal
Konjugat
Dieser Sonic Hedgehog Antikörper ist unkonjugiert
7
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
119
54
52
25
19
12
12
12
11
10
5
3
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN731108
$ 318.45
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN915136 IF (p) Alexa Fluor 488 Rabbit IgG AA 20-70 Anmelden zum Anzeigen Polyclonal 0
1 ABIN915139 IF (p) Alexa Fluor 350 Rabbit IgG AA 20-70 Anmelden zum Anzeigen Polyclonal 0
1 ABIN915140 IF (p) Alexa Fluor 555 Rabbit IgG AA 20-70 Anmelden zum Anzeigen Polyclonal 0
1 ABIN915137 IF (p) Alexa Fluor 647 Rabbit IgG AA 20-70 Anmelden zum Anzeigen Polyclonal 0
1 ABIN731111 IF (p) Cy3 Rabbit IgG AA 20-70 Anmelden zum Anzeigen Polyclonal 0
1 ABIN731113 IF (p) Cy5.5 Rabbit IgG AA 20-70 Anmelden zum Anzeigen Polyclonal 0
1 ABIN731115 IF (p) FITC Rabbit IgG AA 20-70 Anmelden zum Anzeigen Polyclonal 0
1 ABIN731112 IF (p) Cy5 Rabbit IgG AA 20-70 Anmelden zum Anzeigen Polyclonal 0
1 ABIN731114 IF (p) Cy7 Rabbit IgG AA 20-70 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2806354 IF (p) Alexa Fluor 594 Rabbit IgG AA 20-70 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5010502 IF (p) Alexa Fluor 750 Rabbit IgG AA 20-70 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5010501 IF (p) Alexa Fluor 680 Rabbit IgG AA 20-70 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Sonic Hedgehog (SHH) Antikörper
Epitop AA 20-70
(17), (14), (9), (7), (5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(107), (75), (59), (8), (6), (5), (5), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(93), (41), (10), (1)
Klonalität
Polyklonal
Konjugat Dieser Sonic Hedgehog Antikörper ist unkonjugiert
(7), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(119), (54), (52), (25), (19), (12), (12), (12), (11), (10), (5), (3), (1), (1)
Pubmed 8 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Sonic Hedgehog Antikörper

Target Details Sonic Hedgehog Anwendungsinformationen Handhabung Referenzen für anti-Sonic Hedgehog Antikörper (ABIN731108) Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Shh
Isotyp IgG
Plasmids, Primers & others

Target Details Sonic Hedgehog

Produktdetails anti-Sonic Hedgehog Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Sonic Hedgehog Antikörper (ABIN731108) Bilder zurück nach oben
Antigen
Andere Bezeichnung Shh (SHH Antibody Abstract)
Hintergrund

Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).

Subcellular location: Cell membrane

Synonyms: TPT, HHG1, HLP3, HPE3, SMMCI, TPTPS, MCOPCB5, Sonic hedgehog protein, SHH, HHG-1

Gen-ID 6469
UniProt Q15465
Pathways Hedgehog Signalweg, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development

Anwendungsinformationen

Produktdetails anti-Sonic Hedgehog Antikörper Target Details Sonic Hedgehog Handhabung Referenzen für anti-Sonic Hedgehog Antikörper (ABIN731108) Bilder zurück nach oben
Applikations-hinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Sonic Hedgehog Antikörper Target Details Sonic Hedgehog Anwendungsinformationen Referenzen für anti-Sonic Hedgehog Antikörper (ABIN731108) Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Referenzen für anti-Sonic Hedgehog Antikörper (ABIN731108)

Produktdetails anti-Sonic Hedgehog Antikörper Target Details Sonic Hedgehog Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Yang, Wu, Feng, Huang, Liu, Liu, Chen: "Vitamin C plus hydrogel facilitates bone marrow stromal cell-mediated endometrium regeneration in rats." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 267, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Wang, Zhang, Bai, Wang, Du: "Baicalin Attenuates Alcoholic Liver Injury through Modulation of Hepatic Oxidative Stress, Inflammation and Sonic Hedgehog Pathway in Rats." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 39, Issue 3, pp. 1129-40, 2016 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: liver

Bai, Lu, Lin, Xu, Hu, Liang, Hong, Chen: "Sonic hedgehog-mediated epithelial-mesenchymal transition in renal tubulointerstitial fibrosis." in: International journal of molecular medicine, Vol. 37, Issue 5, pp. 1317-27, 2016 Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: kidney

Wu, Zhao, Cheng, Yang, Huang, Meng, Wu, Zhang, Lv, Li: "Melittin induces PTCH1 expression by down-regulating MeCP2 in human hepatocellular carcinoma SMMC-7721 cells." in: Toxicology and applied pharmacology, Vol. 288, Issue 1, pp. 74-83, 2015 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Ma, Li, Li, Yang, Huang, Meng, Zhang, Li: "Geniposide alleviates inflammation by suppressing MeCP2 in mice with carbon tetrachloride-induced acute liver injury and LPS-treated THP-1 cells." in: International immunopharmacology, 2015 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Fan, Wang, Zhao, Liu, Chen, Sun, Zheng: "Sonic hedgehog signaling may promote invasion and metastasis of oral squamous cell carcinoma by activating MMP-9 and E-cadherin expression." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 7, pp. 41, 2014 Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human).

Weiss, Guo, Shan, Shi, Romano, Sinha, Cantley, Guo: "Brg1 determines urothelial cell fate during ureter development." in: Journal of the American Society of Nephrology : JASN, Vol. 24, Issue 4, pp. 618-26, 2013

Du, Feng, Wang, Piao, Cui, Chen, Lei, Sun, Liu, Wang, Li, Yang, Sun, Zhao, Jiang, Li, Jiang: "Curcumin suppresses malignant glioma cells growth and induces apoptosis by inhibition of SHH/GLI1 signaling pathway in vitro and vivo." in: CNS neuroscience & therapeutics, Vol. 19, Issue 12, pp. 926-36, 2013 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Bilder

Produktdetails anti-Sonic Hedgehog Antikörper Target Details Sonic Hedgehog Anwendungsinformationen Handhabung Referenzen für anti-Sonic Hedgehog Antikörper (ABIN731108) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Sonic Hedgehog (SHH) (AA 20-70) antibody (ABIN731108) Formalin-fixed and paraffin embedded human gastric cancer labeled with Anti-SHH Polyc...
SDS-PAGE (SDS) image for anti-Sonic Hedgehog (SHH) (AA 20-70) antibody (ABIN731108) Lane 1: mouse embryo lysates Lane 2: rat brain lysates probed with Anti ShhPolyclonal...
Western Blotting (WB) image for anti-Sonic Hedgehog (SHH) (AA 20-70) antibody (ABIN731108) Mouse embryo lysates probed with Rabbit Anti-Shh Polyclonal Antibody, Unconjugated a...
Flow Cytometry (FACS) image for anti-Sonic Hedgehog (SHH) (AA 20-70) antibody (ABIN731108) Human A549 cells probed with Rabbit Anti-Shh Polyclonal Antibody, Unconjugated .
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) image for anti-Sonic Hedgehog (SHH) (AA 20-70) antibody (ABIN731108) This image was generously submitted by Dr. Guo from Yale School of Medicine. Formalin...
Western Blotting (WB) image for anti-Sonic Hedgehog (SHH) (AA 20-70) antibody (ABIN731108) Mouse stomach lysates probed with Shh Polyclonal Antibody, unconjugated at 1:300 ove...