anti-Hund Sonic Hedgehog Antikörper für ELISA

Recommended Sonic Hedgehog Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Sonic Hedgehog (SHH) Antikörper
  • shh
  • SHH
  • 9530036O11Rik
  • Dsh
  • Hhg1
  • Hx
  • Hxl3
  • M100081
  • HHG1
  • HLP3
  • HPE3
  • MCOPCB5
  • SMMCI
  • TPT
  • TPTPS
  • Xhh
  • hedgehog
  • xshh
  • fc83d08
  • syu
  • vhh-1
  • vhh1
  • wu:fc83d08
  • sonic hedgehog
  • sonic hedgehog protein A
  • sonic hedgehog L homeolog
  • sonic hedgehog a
  • shh
  • SHH
  • Shh
  • shh.L
  • shha
Reaktivität
Hund, Human, Maus, Zebrafisch (Danio rerio)
108
79
59
12
8
7
5
2
2
2
2
2
1
1
1
1
1
1
1
Wirt
Kaninchen
106
42
10
1
Klonalität
Polyklonal
Konjugat
Dieser Sonic Hedgehog Antikörper ist unkonjugiert
8
4
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
129
55
50
28
20
14
13
13
11
10
5
3
1
1
Hersteller
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Bilder

Produktnummer ABIN2462795
$ 446.88
Zzgl. Versandkosten $45.00

General

Antigen Sonic Hedgehog (SHH) Antikörper
Reaktivität Hund, Human, Maus, Zebrafisch (Danio rerio)
(108), (79), (59), (12), (8), (7), (5), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(106), (42), (10), (1)
Klonalität
Polyklonal
Konjugat Dieser Sonic Hedgehog Antikörper ist unkonjugiert
(8), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(129), (55), (50), (28), (20), (14), (13), (13), (11), (10), (5), (3), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Sonic Hedgehog Antikörper

Target Details Sonic Hedgehog Anwendungsinformationen Handhabung Bilder
Reinigung Antibody is purified by peptide affinity chromatography method.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SHH.
Plasmids, Primers & others

Target Details Sonic Hedgehog

Produktdetails anti-Sonic Hedgehog Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung SHH (SHH Antibody Abstract)
Hintergrund SHH is a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE). It is also thought that mutations in its gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.This gene, which is expressed only during embryogenesis, encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres. HPE is manifested by facial deformities. In addition, it is thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.
Molekulargewicht 28 kDa
Gen-ID 6469
NCBI Accession NP_000184
UniProt Q15465
Pathways Hedgehog Signalweg, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development

Anwendungsinformationen

Produktdetails anti-Sonic Hedgehog Antikörper Target Details Sonic Hedgehog Handhabung Bilder zurück nach oben
Applikations-hinweise SHH antibody can be used for detection of SHH by ELISA at 1:312500. SHH antibody can be used for detection of SHH by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Sonic Hedgehog Antikörper Target Details Sonic Hedgehog Anwendungsinformationen Bilder zurück nach oben
Format Lyophilized
Rekonstitution Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Konzentration 1 mg/mL
Buffer Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handhabung As with any antibody avoid repeat freeze-thaw cycles.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung For short periods of storage (days) store at 4 °C. For longer periods of storage, store SHH antibody at -20 °C.

Bilder

Produktdetails anti-Sonic Hedgehog Antikörper Target Details Sonic Hedgehog Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Sonic Hedgehog (SHH) antibody (ABIN2462795) anti-Sonic Hedgehog (SHH) antibody