anti-Maus Patched 2 Antikörper für Western Blotting

Recommended Patched 2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Patched 2 (PTCH2) Antikörper
  • PTC2
  • ptc2
  • lep
  • ptc1
  • Ptch1
  • ptc-2
  • xptc-2
  • xptch-2
  • patched-2
  • ptch2
  • ptc-1
  • ptch1
  • patched 2
  • patched 1
  • patched 2 S homeolog
  • patched 2 L homeolog
  • PTCH2
  • Ptch2
  • ptch1
  • ptch2.S
  • ptch2.L
  • ptch2
Epitop
N-Term
5
5
4
2
2
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
27
6
3
2
1
1
1
1
1
1
Wirt
Kaninchen
21
6
1
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
26
8
6
3
2
2
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN2782247
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.22672 ABIN152263 ICC IHC (fro) IF IHC (p) IHC ELISA WB Rabbit AA 226-235 Anmelden zum Anzeigen Polyclonal
3.22672 ABIN3032167 WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN1089894 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN1089895 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN2443031 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Patched 2 (PTCH2) Antikörper
Epitop N-Term
(5), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
(27), (6), (3), (2), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(21), (6), (1)
Klonalität
Polyklonal
Applikation Western Blotting (WB)
(26), (8), (6), (3), (2), (2), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Patched 2 Antikörper

Target Details Patched 2 Anwendungsinformationen Handhabung Referenzen für anti-Patched 2 Antikörper (ABIN2782247) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN982410.
Sequenz LAQEALPENA SQQIHAFSST TLDDILHAFS EVSAARVVGG YLLMLAYACV
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against PTCH2. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human PTCH2

Target Details Patched 2

Produktdetails anti-Patched 2 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Patched 2 Antikörper (ABIN2782247) Bilder zurück nach oben
Antigen
Andere Bezeichnung PTCH2 (PTCH2 Antibody Abstract)
Hintergrund PTCH2 is a member of the patched protein family. The patched protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. The gene encoding PTCH2 is shown to be mutated in a medulloblastoma and in a basal cell carcinoma, suggesting that it plays a role in the development of some tumors. This gene encodes a member of the patched gene family. The patched protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. This gene is shown to be mutated in a medulloblastoma and in a basal cell carcinoma, suggesting that it plays a role in the development of some tumors. Alternative transcript variants have been described, but their biological function has not been determined. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-10 AF119569.1 1-10 11-534 AY359016.1 3-526 535-2066 AF087651.1 523-2054 2067-2509 AF119569.1 2067-2509 2510-2520 AF087651.1 2498-2508 2521-2700 AF119569.1 2521-2700 2701-3620 AY358555.1 2689-3608 3621-3624 AF087651.1 3609-3612
Alias Symbols: PTC2
Protein Interaction Partner: ARRB1, DHH, SMO, IHH, SHH,
Protein Size: 1203
Molekulargewicht 130 kDa
Gen-ID 8643
NCBI Accession NM_003738, NP_003729
UniProt Q9Y6C5
Forschungsgebiet Cancer, Cell Cycle, Transcription Factors
Pathways Hedgehog Signalweg

Anwendungsinformationen

Produktdetails anti-Patched 2 Antikörper Target Details Patched 2 Handhabung Referenzen für anti-Patched 2 Antikörper (ABIN2782247) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 1203 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Patched 2 Antikörper Target Details Patched 2 Anwendungsinformationen Referenzen für anti-Patched 2 Antikörper (ABIN2782247) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Patched 2 Antikörper (ABIN2782247)

Produktdetails anti-Patched 2 Antikörper Target Details Patched 2 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: "The DNA sequence and biological annotation of human chromosome 1. ..." in: Nature, Vol. 441, Issue 7091, pp. 315-21, 2006

Bilder

Produktdetails anti-Patched 2 Antikörper Target Details Patched 2 Anwendungsinformationen Handhabung Referenzen für anti-Patched 2 Antikörper (ABIN2782247) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Patched 2 (PTCH2) (N-Term) antibody (ABIN2782247) anti-Patched 2 (PTCH2) (N-Term) antibody