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Hairy and Enhancer of Split 4 Produkte

(Hairy and Enhancer of Split 4 (HES4))

Kategorien

Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. Promotes floor plate development and prechordal plate development. Required for lens development as early as the stage of lens field formation, partly through regulation of gene expression of the cell cycle inhibitor cdknx/p27(xic1). Required for formation of the neural crest downstream of multiple signaling pathways, and acts at the neural plate border via both DNA-binding dependent and independent mechanisms. Also acts via repressor- dependent and repressor-independent mechanisms in early gastrulae to establish the prospective anterior prechordal mesoderm identity in the Spemann organizer\; induces specific genes independently from direct transcriptional regulation, and represses the genes specific for neighboring tissues through direct transcriptional repression. Modulates lateral inhibition during notch signaling and regulates the cell context dependent effects of notch (which can have inhibitory, permissive or enhancing roles in muscle or neural differentiation). Inhibits myogenesis (By similarity).

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Ausgewählte Hairy and Enhancer of Split 4 Kategorien

Hairy and Enhancer of Split 4 Antikörper

High quality antibodies with extensive validation data.

Hairy and Enhancer of Split 4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Hairy and Enhancer of Split 4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN2565591
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Cow, Human, Monkey
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN202082
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN202081
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Hairy and Enhancer of Split 4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1306551
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3081428
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2722664
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Hairy and Enhancer of Split 4 Produkten

El Yakoubi, Borday, Hamdache, Parain, Tran, Vleminckx, Perron, Locker: "Hes4 controls proliferative properties of neural stem cells during retinal ontogenesis." in: Stem cells (Dayton, Ohio), Vol. 30, Issue 12, pp. 2784-95, (2012) (PubMed).

Synonyme und alternative Namen zu Hairy and Enhancer of Split 4

hes family bHLH transcription factor 4 (HES4), hes family bHLH transcription factor 4 (hes4), hes family bHLH transcription factor 4 L homeolog (hes4.L), hes family bHLH transcription factor 4 S homeolog (hes4.S), bHLHb42, hairy2, hairy2a, hairy2b, hes1, hes4a, hes4b, Xhairy2, XHairy2a, Xhairy2a, Xhairy2b

Bezeichner auf Proteinebene für Hairy and Enhancer of Split 4

  • bHLH factor Hes4
  • class B basic helix-loop-helix protein 42
  • hHES4
  • transcription factor HES-4
  • Protein hairy-2
  • hairy and enhancer of split 1
  • transcription factor HES-4-B
  • hairy2b
  • Protein hairy-2a
  • Hairy and enhancer of split 4-B
  • transcription factor HES-4-A
  • Hairy and enhancer of split 4-A
  • basic-helix-loop-helix transcription factor hairy2
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